Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"beta-2-microglobulin"”.
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A fluidized immunoadsorption device for removing beta-2-microglobulin from whole blood : a potential treatment for dialysis-related amyloidosis
… has been associated with the accumulation of 2-microglobulin (2m). Excluding transplantation, existing kidney replacement technologies are believed to remove insufficient quantities of P2m for the prevention of DRA, as they are non-specific and based on size-exclusion. A proposed DRA therapy is …
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The Characterization of Hemodialysis Membranes in Miniaturized Dialyzers
… to ultrafiltration coefficient, clearance of Beta-2 Microglobulin (B2M), and SC of B2M.These outcomes suggest that the miniaturized dialyzers can effectively differentiate performance characteristics representing hemodialysis membrane and fiber design. This indicates that the miniaturized …
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Integrative genomic approaches to dissecting host-tumor and host-pathogen immune processes
… association with cytolytic activity, including beta-2- microglobulin (B2M), HLA-A, -B and -C and Caspase 8 (CASP8), highlighting loss of antigen presentation and blockade of extrinsic apoptosis as key strategies of resistance to cytolytic activity. Genetic amplifications were also associated …
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Untersuchungen zur Rolle von Zytokinen bei der Beta-2-Mikroglobulin-Synthese in verschiedenen humanen Zelltypen
… incriminated in the pathogenesis of elevated beta-2-microglobulin (beta-2-M) serum concentrations in patients undergoing haemodialysis with so-called bioincompatible dialyser membranes. However, neither the source of the elevated serum beta-2-M nor the precise role of monocytic cytokines in …
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Investigating biomarkers in clinical samples that are predictive of response in multiple myeloma
… (ZAG), Serum Amyloid A protein (SAA), Beta-2-microglobulin (B2M), had higher abundance level with fold changes of 1.31 (p=0.00044), 1.32 (p=0.0077), 1.48 (p= 0.0000022), 3.01 (p=0.006) and 1.96 (p=0.0015) fold increase in non-responders compared to responders, respectively. In contrast …
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Beta2-microglobulin and antichromatin antibodies can be a disease activity markers in Systemic Lupus Erythematosus in Koreans
BACKGROUNDS: Beta2-microglobulin and antichromatin antibodies have been described in patients with systemic lupus erythematosus (SLE) and it has been suggested that their presence is associated with lupus disease activity. We have investigated the clinical significance of beta2-microglobulin and …
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Subcellular Fractionation Methods for the Quantification of Endogenous Protein in Human Liver Using Targeted Proteomics
… First, human liver neonatal Fc receptor and beta 2-microglobulin were enriched in a post-nuclear supernatant, and a UPLC-MRM method was developed and validated to quantify these two proteins. Our quantitative results and determination of interindividual variability will aid the future …