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Showing 1 to 9 of 9 for “"benzimidazol"”.
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Synthesis and characterization of 2-chloro-3-benzylthiopyrrolo[1,2-a]- benzimidazol-1-one and 2,3-di(benzylthio)pyrrolo[1,2-a]benzimidazol-1-one.
… and found to give 2,3-dichloropyrrolo[1,2-a]- benzimidazol-1-one as the major product. Chlorine substitution in 2,3-dichloropyrrolo[1,2-a]benzimidazol-1-one by added benzylthiol occurs in the presence of pyridine to provide the corresponding monosulfide and disulfide derivatives. The first …
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Bazı yeni heterosiklik bileşiklerin sentez, yapı aydınlatmaları ve antimikrobiyal etki çalışmaları
… vitro aktivite sonuçları incelendiğinde yeni benzimidazol türevlerinin antibakteriyel etkilerinin standart suşlara karşı referans ilaçlardan daha zayıf; ancak ilaçlara dirençli suşlara karşı referans bileşikler ile kıyaslanabilir hatta bazılarına kıyasla daha iyi olduğu gözlenmiştir. Bileşiklerin …
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Monosacchacharid-Konjugate von Inhibitoren der O6-Methylguanin-DNA Methyltransferase, der Poly-(ADP-ribose) Polymerase und des SWITCH Phänomens des HIV Hüllproteins gp120 : Synthese, biologische Aktivität und Struktur-Wirkungsbeziehungen
… zu MGMT-Inhibitor-Glucosiden, eine Hydroxyphenyl-benzimidazol-Grundstruktur zu PARP-Inhibitor-Glucosiden und Isochinolindion-Grundstrukturen zu SWITCH-Inhibitor-Glucosiden umgesetzt. Gegenüber dem 'Goldstandard' der MGMT-Inhibitoren, dem O6-Benzylguanin (O6BG), konnten durch schrittweise …
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Surface Modification of Nanoparticles Using Controlled Radical Polymerization For Designed Interfaces
… part of this work describes the synthesis of benzimidazole side chain containing monomers and polymers. A new monomer 2-(4-vinylphenyl)-1H-benzo[d]imidazole containing a radically polymerizable group was synthesized and progress was made towards understanding its polymerization. RAFT …
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Investigations into the use of continuous low-level medication for the control of helminths in the ruminant
… and briefly oxfendazole (5-(phenylsulfinyl)-IH-benzimidazol-2yl) carbamate) were also examined. In Section 2, the development of an intra-ruminal bolus incorporating thiophanate and designed to release drug at a predetermined rate over an extended period of time is described. Experiments were …
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Avances en la química de coordinación de los tetrilenos pesados
… los de tipo imidazol E(NtBu)2C2H2 (E = Si, Ge) o benzimidazol E(NCH2tBu)2C6H4 (E = Si, Ge, Sn) como TPs cíclicos simples. Como resultado se han preparado los primeros bis(amido)germilenos y -estannilenos de rutenio, así como los primeros complejos de oro conteniendo un estannileno neutro. También …
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Cobalt catalysts towards parahydrogen induced polarization
… [MesCCC = bis(2,4,6-trimethylphenyl-benzimidazol-2-ylidene)phenyl), py = pyridine] , towards hyperpolarization of substrates via PHIP chemistry. In Chapter 2, the development of structural and electronic variants of the CCC ligand platform is discussed. The synthesis of a chiral …
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Catalytic hydrofunctionalization and small molecule reactivity at a low-valent cobalt center supported by a bis(carbene) CCC pincer ligand
… pincer ligand, (DIPPCCC = bis(diisopropylphenyl-benzimidazol-2-ylidene)phenyl), a platform which provides highly-donating carbenes and an aryl carbon linkage to the coordinated metal. Multinuclear NMR spectroscopies, cyclic voltammetry, X-ray crystallography, and EPR spectroscopies have …