Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 58 for “"basal cell"”.
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Detecting basal cell carcinoma in skin histopathological images using deep learning
… image classification to detect the presence of Basal Cell Carcinoma (BCC) in digital skin histological images. Since digital histology images are extremely large, we first focused on determining the presence of BCC at the patch level, using pre-trained deep convolutional neural networks as …
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THRESHOLDING METHODS FOR LESION SEGMENTATION OF BASAL CELL CARCINOMA IN DERMOSCOPY IMAGES
… that perform poorly on dermoscopy images of basal cell carcinoma (BCC), which is the most common skin cancer. One of the reasons for poor lesion detection performance is that there are very few algorithms that detect BCC borders, because they are difficult to segment, even for dermatologists. …
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Molecular Classification of Basal Cell Carcinoma of Skin by Gene Expression Profiling
Non-melanoma skin cancers (NMSC) including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are more common kinds of skin cancer. Although these tumors share common pathological and clinical features, their similarity and heterogeneity at molecular levels are not fully elaborated yet. …
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Desensitization Of Basal Cell Carcinoma To The Anti-Tumoral Effect Of Vitamin D
… BCC are few, and mostly are animal models or cell cultures. The main goal for this study is to interpret the impact of vitamin D status on the onset and progression and possibly treatment of basal cell carcinoma. Three tissue samples were collected from BCC patients (Cancer, Proximal, and …
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Evaluation of tumour-associated antigens to optically label cutaneous basal cell carcinoma for surgical excision
Basal cell carcinoma (BCC) is the most common skin cancer worldwide, with South Africa having the highest incidence rate only after Australia. The most effective treatment modality for BCC is tumor excision via Mohs surgery (pioneered by Dr. Frederic Mohs of the University of Wisconsin in 1930), a …
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Elucidating the Role of Canonical Wnt/β-Catenin Signaling in Primary Human Airway Basal Cell Proliferation and Mucociliary Differentiation Capacity in vitro
North Carolina State University Theses Biomanufacturing Training and Education Center.
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Apoptosis and Necroptosis in Basal Cell and Spinocellular Carcinoma of the Skin // Апоптоза и некроптоза при базоцелуларен и спиноцелуларен карцином на кожа
… epidermis are of two main histological types: basal cell carcinoma (BCC) and spinocellular or squamous cell carcinoma (SCC). Since 2000, Bulgaria has seen a steady increase in the incidence and mortality of these neoplasms. Apoptosis is a process of programmed cell death. Disruptions in the …
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Downstream Signal Transduction Pathway in Human Middle Ear Cholesteatoma
… The proliferation and differentiation of cells in specialized tissues and the expression of their properties are under the control of a large number of regulatory processes and complex interactions called signal transduction. The signal transduction pathway may be initiated by the external …
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Role of downstream signal transduction molecules of congenital middle ear cholesteatoma according to its site of origin
… The proliferation and differentiation of cells in specialized tissues and the expression of their properties are under the control of a large number of regulatory processes and complex interactions called signal transduction. The signal transduction pathway may be initiated by the external …
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Incidence of cancer among residents of high temperature geothermal areas in Iceland: A census based study 1981 to 2010
… lymphoma 3.25 (95% CI 1.73 to 6.07). The HR for basal cell carcinoma of the skin was 1.61 (95% CI 1.10 to 2.35). The HRs were increased for cancers of the nasal cavities, larynx, prostate, thyroid gland and for soft tissue sarcoma; however the 95% CI included unity. Conclusion: More precise …
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Initial implementation of epidermal electronic systems into a clinical setting to monitor cutaneous wound healing
… optimize data acquisition after the removal of basal cell carcinoma. Initial results are promising and more patients will be included to determine the feasibility, reliability, and multifunctional potential of epidermal electronic devices for wound management and other non-invasive applications.
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Epidermal growth factor receptor in equine gastric stratified squamous mucosa: effect of progressive ulceration on receptor density
… at four sites within the epithelium from the basal cell layers to the lumen in the ulcer/erosion margin, erosion bed, and 10-14 mm distant from the lesion.
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Stellenwert der optischen Kohärenztomographie in der Beurteilung epithelialer Hauttumoren : eine offene klinische Studie zur nicht-invasiven In-vivo-Anwendung der optischen Kohärenztomographie
… have been examined by OCT within the study – 10 basal cell carcinoma, 10 Morbus Bowen and 14 acitinic keratosis – and they have been compared with corresponding histological slides. Micromorphological characteristics could be developed for all three tumor entities. The preoperative diagnostic was …
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Basil cell carcinoma: an immunohistochemical assessment of P53, BCL-2 and CD138 in low and high-risk histological subtypes
Basal cell carcinoma (BCC) is the leading cancer in males and the second commonest cancer in females in South Africa. The cost to the health sector is expected to rise given the increasing global incidence rates, particularly of aggressive BCCs. Improved understanding of BCC is paramount to enhance …
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Aspects of skin cancer diagnosis in clinical practice
… The three most common skin cancers are basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and malignant melanoma (MM). A correct diagnosis is crucial for an efficient and tailored treatment for the skin cancer patient. The purpose of this thesis was to evaluate different aspects …
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HPV E6 inhibits E6AP to regulate epithelial homeostasis by modulating keratinocyte differentiation commitment and YAP1 activation
… infections by modulating homeostasis of infected basal cell to ensure persistence. Using FUCCI and cell-cell competition assays, we established the role of two common viral targets of low-risk and high-risk E6 proteins, E6AP and NHERF1, on the key components of epithelial homeostasis: cell …
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Pioneer Factors Compete for Epigenetic Factors in Switching Stem Cell Fates
<p>During development, progenitor cells can activate one cell fate while simultaneously silencing another, a process that is tightly regulated in adult tissues. However, this process is often derailed in diseases such as cancers, leading to uncontrolled growth and malignancy. At the crossroads of …
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Force-induced calcium concentration change and focal adhesion translocation : effects of force amplitude and frequency
Vascular endothelial cells rapidly sense and transduce external forces into biological signals through a process known as mechanotransduction. Numerous biological processes are involved in mechanotransduction, including calcium signaling and activation of focal adhesion sites, but little is known …
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Chemically Based Interrogation of Smoothened, a Proto-Oncogenic Component of the Hedgehog Signal Transduction Pathway
… target in Hh-associated cancers including basal cell carcinoma (BCC) and medulloblastoma. While a Smo antagonist is now approved for the management of BCC, therapeutic strategies focused on Smo continue to encounter issues of intrinsic and acquired drug resistance. To overcome these …
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Molecular Drivers of Bladder Cancer Motility
… progression is measured by the degree of tumor cell invasion into the bladder wall and dissemination to distant sites. The study of BC cell motility will both enable development of anti-invasion therapeutics to limit progression of early-stage disease and improve our understanding of the …
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