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Showing 1 to 5 of 5 for “"baicalein"”.
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Baicalein, a novel anti-diabetic compound
… diabetes treatment. Studies have reported that baicalein, a flavone originally isolated from the roots of Chinese herb Scutellaria baicalensis, has various claimed beneficial effects on health, such as anti-oxidant, anti-viral, anti-thrombotic, and anti-inflammatory effects. However, it is …
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Discovery and Mechanisms of Small Molecule Amyloid Formation Inhibitors
… show that the catechol moiety present within baicalein, oleuropein and rosmarinic acid are critical for their anti-amyloid functions, including exerting cell rescue effects against amylin induced cytotoxicity. We also demonstrate that in general, autoxidation enhances the anti-amyloid potency …
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Synthetic and spectroscopic studies of 6-substituted chromone derivatives
… found in the plant kingdom; for example, baicalein was used as a diuretic and anti-allergic drug in ancient Chinese medicine. A range of chromone-2-carboxylic acids were synthesized from six substituted 2- hydroxyacetophenones. From these chromone-2-carboxylic acids, the acid chlorides …
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Science Based Authentication of Dietary Supplements: Studies on the Chemical Constituents, Analytical Method and Biological Activities of Scutellaria Spp and Pfaffia Paniculata
… as several characteristic flavonoids, such as baicalein, baicalin, wogonin, and chrysin etc. that provides some information on possible new application of skullcap, especially American skullcap, for the treatment of diabetic-related diseases. Also the potent activity of these flavonoids on …
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Role of the Leukotriene B4 Metabolic Pathway in Human Pancreatic Cancer
… inhibitor NDGA, the selective 12-LOX inhibitor baicalein, as well as the selective LTB4 receptor antagonist LY293111, all markedly attenuated the growth of AsPC-1 and HPAC pancreatic cancer xenografts in athymic mice. These compounds also induced marked apoptosis of these tumor xenografts.|In …