Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"bacteriolysis"”.
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Elucidating Human Inflammasome Responses To Legionella Pneumophila And Lipopolysaccharide Variants
… the rupture of pathogen-containing vacuoles and bacteriolysis of cytosolic bacteria in order to release pathogen-derived products, such lipopolysaccharide (LPS), into the cytosol for downstream host sensing and inflammasome activation. In contrast to mice, which possess 11 GBPs, humans have 7 …
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Investigation into the toxicity and membrane interactive properties of a range of cationic photosensitisers with potential application to Photoantimicrobial Chemotherapy
… Blue showed increased levels of bacteriolysis (from 6% to 9%, and 9% to 11%, respectively). Consistent with their inherent lytic abilities, each of the PhBPs studied showed the ability to interact with lipid monolayers mimetic of bacterial membranes (DOPG / DOPE, 30:70 molar …
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Towards ultrahigh-throughput phenotypic screening using microfluidic droplets and functionalised polyacrylamide beads
… phenotypic screen for bacteriolysis. I show that this assay is sensitive to antimicrobial peptide-induced lysis under treatment conditions which could theoretically be achieved using microfluidics and bead protein capacity levels as demonstrated in Chapter 1, although …
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Spore-forming bacteria as pharmaceutical factories
Many Bacilli form dormant structures, spores, which routinely survive physical, chemical and biological challenge. How do spores encapsulate their contents, and could it be possible to mimic or adapt them to make better drug products? Key spore component 2,6-dipicolinic acid (DPA) is necessary for …