Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"bacterial pneumonia"”.
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Growth of Pigs With Viral and Bacterial Pneumonia
Infection with PRRSV increased serum IL-1beta and IL-6, increased MSTN and mRNA in skeletal muscle, and decreased FI, WG, PA and the mass of several skeletal muscles, but neither Mh nor the MhxPRRSV interaction were significant. The Mh-induced lung lesions, however, were 3- to 5-times greater in …
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Bacterial pneumonia hospitalization and pneumonia inpatient mortality in Texas, 1999-2007
Bacterial pneumonia has a disproportionate impact on the elderly. It is considered as an ambulatory care-sensitive condition by the Agency for Healthcare and Research (AHRQ), for which good outpatient care can potentially prevent the need for hospitalization or for which early intervention can …
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Role of NOD2/RIP2 signaling in acute bacterial pneumonia and sepsis
Bacterial pneumonia and sepsis are two important causes of mortality in the world. Emergence of multidrug resistant bacteria has necessitated the development of new treatment and/or prevention strategies to augment host immune defense. In this context, the innate host defense is critical in …
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A Novel Mechanism of Enhanced Susceptibility to Bacterial Pneumonia in Influenza-infected Hosts
… pathways, including facilitation of secondary bacterial pneumonia from pathogens such as Streptococcus pneumoniae. Lungresident alveolar macrophages (AMs) act as the first line of innate cellular immunity against respiratory bacterial pathogens, including pneumococcus. Therefore, they represent …
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Investigating The Roles of Lung Epithelial Stat3 In Therapeutically Inducible Resistance to Acute Bacterial Pneumonia.
… in therapeutically inducible resistance to acute bacterial pneumonia.</p> <p>Vikram Vitthal Kulkarni, M.S.</p> <p>Advisory Professor: Scott Evans, MD.</p> <p>The lung epithelium is a dynamic tissue capable of displaying structural and functional plasticity in response to pathogenic challenges. Our …
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MEMORY TH17 CELLS IN THE LUNG DURING SECONDARY BACTERIAL PNEUMONIA FOLLOWING INFLUENZA A VIRUS INFECTION
Secondary bacterial infection is the primary cause of morbidity and mortality associated with influenza A virus (IAV) infection. Specifically, nontypeable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae (Sp) are the most common cause of lethal secondary bacterial pneumonia in IAV …
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The Potential Role of Cathelicidin Peptides for the Treatment of Lower Respiratory Tract Infections
Bacterial pneumonia, one of the leading causes of hospitalization and mortality worldwide, is caused by the colonization of invasive bacteria in the airways, leading to pulmonary inflammation and lung dysfunction. The development of antibiotic resistant bacterial infections has limited the …
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Community correlates of pneumonia hospitalization and mortality among persons 65 years and older in Texas counties
… examined the effect of health care quality on pneumonia among persons 65+ in Texas counties, and considered how community (county) characteristics such as prosperity and racial/ethnic homogeneity impact population health and well-being.\r\n The project applied Evans and Stoddart determinants of …
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Diagnostic accuracy of C-reactive protein and procalcitonin, compared with composite reference standards, to discriminate between tuberculosis, Pneumocystis jirovecii pneumonia and bacterial pneumonia in HIV-infected inpatients meeting WHO criteria for seriously ill
Tuberculosis, bacterial community-acquired pneumonia (CAP), and Pneumocystis jirovecii pneumonia (PJP) are the commonest causes of hospitalisation in HIV-infected individuals. Prompt diagnosis and treatment initiation are important to reduce morbidity and mortality, but are hampered by overlap in …
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The Balance of Interferon-γ and Interleukin-10 during Influenza A Virus Infection Complicated by Methicillin-Resistant Staphylococcus aureus Superinfection
… a protective immune response against viral and bacterial infections, but an overzealous response can lead to the development of acute respiratory distress syndrome (ARDS). ARDS is a highly lethal inflammatory lung injury that is associated with dysregulated cytokine production and decreased lung …
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Mild traumatic brain injury augments innate immune responses through neurokinin and cholinergic signaling
Pneumonia is the second leading cause of disability-adjusted life-years lost worldwide and the eighth leading cause of death in the United States. Traumatic brain injury (TBI) patients have classically been considered immunosuppressed, but recent research reported that mild head trauma patients …
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Cellular Dynamics and Disease Outcome of Type 3 Streptococcus pneumoniae Clinical Isolates Differ Between Strains
Streptococcus pneumoniae is a bacterial pathogen that continues to be a major cause of disease around the world. It is not only the number one cause of bacterial pneumonia but also the cause of about 15% of the deaths of children under 5 around the world. There is a lot of research done on this …
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Alternations in the Splenic Marginal Zone with Age
… the prevention of diseases such as Streptococcus pneumonia. It has been widely reported that with the advancement of age there is a higher rate of mortality as a result of bacterial pneumonia when compared to the young. My objective here was to determine if there are age related changes in the …
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Hypoxia and the regulation of host responses to acute bacterial pulmonary infections
Introduction – Severe pulmonary bacterial infections are frequently complicated by systemic hypoxaemia and, in the context of acute respiratory distress syndrome (ARDS), inappropriately prolonged neutrophilic inflammation. This combination of acute hypoxaemia and persistent inflammatory response …
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Interferons in Influenza A Virus and Streptococcus Pneumoniae Co-Pathogenesis
Secondary pneumococcal pneumonia postinfluenza significantly increases the disease burden associated with influenza A virus (IAV) infection. IAV induced interferons (IFN) play a crucial role in antiviral immunity. However, recent reports have indicated that influenza-induced IFN-I and IFN- γ …
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Influenza A Virus PB1-F2 Protein: its Role in Pathogenesis
… virus infection and post-influenza secondary bacterial pneumonia in mice. It is a multifunctional and enigmatic protein with diverse functions attributed to it and the precise contribution of PB1-F2 to the IAV life cycle in avian and mammalian hosts remains largely unknown. In the …
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Characterization of Influenza:Streptococcus pneumoniae synergistic disease and potential for disease alleviation via sphingolipid therapy
… with influenza also test positive for bacterial pneumonia, the most common agent being Streptococcus pneumoniae. Although all individuals are subject to this viral:bacterial synergistic disease, the young, elderly, and immunocompromised are the most susceptible. Previous studies have …