Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 21 for “"bacterial meningitis"”.
-
Hearing loss in experimental bacterial meningitis
Experimental meningitis was induced in pigmented guinea pigs by subarachnoid inoculation of \(1 \times 10^9\) Escherichia coli K-12 or \(3 \times 10^7\) CFU Streptococcus pneumoniae serotype 2 D39 (NCTC 7466) or PLN-A, \(\Delta\)NA1 or \(\Delta\)HY1, defined isogenic derivatives of D39 deficient in …
-
Acute Bacterial Meningitis in Zambian children: Highlighting the changing pattern in the Aetiology of Bacterial Meningitis in Zambia
A hospital based prospective study on Acute Bacterial Meningitis (ABM) in Zambian Children was done in the department of Paediatrics, University Teaching Hospital Lusaka over a period of six months in the hot dry season (1st August to the end of November) of the years 1992 and 1993. The aim and …
-
Acute Bacterial Meningitis in Zambian children: Highlighting the changing pattern in the Aetiology of Bacterial Meningitis in Zambia
A hospital based prospective study on Acute Bacterial Meningitis (ABM) in Zambian Children was done in the department of Paediatrics, University Teaching Hospital Lusaka over a period of six months in the hot dry season (1st August to the end of November) of the years 1992 and 1993. The aim and …
-
Bacterial meningitis in neonates and children South Africa
Acute bacterial meningitis is defined as the inflammation of the meninges. It is caused by various bacteria and the specific aetiology is age dependant. In the neonatal period the causative organisms are: Group B streptococci, Gram - negative bacilli (e.g.: E. coli, Klebsiella spp, Enterobacter …
-
Reducing the Burden of Bacterial Meningitis in the African Meningitis Belt After MenAfriVac
The African meningitis belt - a semi-arid region stretching from Senegal to Ethiopia - experiences the highest incidence of bacterial meningitis in the world, characterised by seasonal fluctuations in endemic disease, localized outbreaks, and multiennial epidemics. MenAfriVac, a serogroup A …
-
Exploring the audiological management of young children (0-6 years) diagnosed with bacterial meningitis
… (LMIC). South Africa has a high prevalence of bacterial meningitis (BM), especially in children under the age of five. BM is also one of the commonest causes of acquired hearing loss in children. Given the fluctuating and transient nature of BM-related hearing loss, there is a need for an …
-
Community acquired bacterial meningitis and meningococcal septicaemia amongst adults in England and Wales : epidemiology and clinical management
<b>Background:</b> Bacterial meningitis and meningococcal septicaemia are important causes of morbidity and mortality in the UK and elsewhere. There have been achievements in paediatric care, including vaccination; however mortality amongst otherwise healthy young adults remains high. …
-
Profile of acute bacterial meningitis in children aged between 1 and 59 months admitted to the paediatric wards at the UTH, Lusaka
… prospective study on the profile of acute bacterial meningitis in children aged between 1 and 59 months admitted to the paediatric wards at the UTH, Lusaka was carried out in the Department of Paediatrics and Child health, University Teaching Hospital, Lusaka from 1 st April 2002 to 31 st …
-
Neurocognitive impairment following central nervous system infections in Kenyan children as detected by event related potentials
… Africa, namely falciparum malaria, acute bacterial meningitis (ABM) and human immune-deficiency virus (HIV). Four groups of children were recruited: children previously admitted with severe falciparum malaria (n= 50), or acute bacterial meningitis (n = 65), or mY-infected (n= 39) or were …
-
Use of the PCR technique to diagnose meningitis in children admitted to Red Cross War Memorial Children’s Hospital
Introduction: Viral meningitis (VM) is more common than bacterial meningitis (BM) and is a self-limiting disease. Clinicians still tend to admit patients with VM and treat them for BM because they fear the morbidity and mortality that is associated with a delay in treating or not treating BM. …
-
On Brain Oedema
Traumatic brain injury and bacterial meningitis may at a glance appear as two different disease entities. The host reaction, however, to both trauma and infection involves a strong inflammatory response, with the classical symptomology of rubor, tumor, calor, dolor et functio laesa. Tumor, …
-
Dysphagia in children (0-12 years) recovering from tuberculosis meningitis (TBM)
Background information: Tuberculous meningitis (TBM) is the most severe extra-pulmonary complication of tuberculosis (TB) and also the most common bacterial meningitis in the Western Cape. The consequences of childhood TBM include poor motor and neurological outcomes which could lead to dysphagia. …
-
The Role of the ITAM-containing CEACAM3 Receptor in the Neutrophil Response to Infection by Neisseria gonorrhoeae
Bacterial species of the genus Neisseria include pathogens that are responsible for diseases of humans including bacterial meningitis (Neisseria meningitidis) and the sexually transmitted disease gonorrhea (Neisseria gonorrhoeae). These diseases are often characterized by a massive influx and …
-
ΜΕΛΕΤΗ ΠΑΡΑΜΕΤΡΩΝ ΕΓΚΕΦΑΛΟΝΩΤΙΑΙΟΥ ΥΓΡΟΥ ΣΕ ΘΕΡΑΠΕΙΑ ΠΕΙΡΑΜΑΤΙΚΗΣ ΜΗΝΙΓΓΙΤΙΔΑΣ ΑΠΟ HAEMOPHILUS INFLUENZAE TYPE B
… EXPERIMENTAL HAEMOPHILUS INFLUENZAE TYPE B (HIB) MENINGITIS WERE ASSESSED. IN THE FIRST PART THE ROLE OF HIB CAPSULE AND LIPOPOLYSACCHARIDE IN THE INDUCTION OF MENNIGEAL INFLAMMATION WERE EVALUATED. A MINIMAL INFLAMMATORYRESPONSE WAS FOUND FOLLOWING INTRACISTERNAL INOCULATION OF PURIFIED HIB …
-
Studies of the NAD metabolism of Haemophilus influenzae
… intact NAD. This organism, the primary cause of bacterial meningitis, is incapable of synthesis of pyridine nucleotides from the usual precursors. An externally directed nucleotide pyrophosphatase was extracted from the organism and purified 700-fold using ammonium sulfate precipitation, …
-
Molecular Mechanisms Involved in Escherichia coli K1 and Haemophilus influenzae Type a Blood-Brain Barrier Impairment
… which they share a common basement membrane. Bacterial meningitis is a common and severe Central Nervous System (CNS) infection, caused by different pathogens, including Escherichia coli K1 (E. coli K1) and Haemophilus influenzae type a (Hia). During E. coli K1 meningitis, CNS cells release …
-
The use of molecular diagnostic methods to improve the detection of the common bacterial and viral causes of community acquired meningitis in children in South Africa
… of the expected CSF findings clearly aligning to bacterial or viral infection. Reduced sensitivity is commonly observed chiefly due to empiric antibiotic treatment leading to bacterial culture negative results. This leads to costly hospital admissions and unnecessarily prolonged treatment for the …
-
Purification and characterization of malate dehydrogenase and 6- phosphogluconate dehydrogenase from Haemophilus influenzae
… influenzae, the primary causative factor in bacterial meningitis, displays a unique growth requirement for intact NAD. Selective inhibitors of the pyridine nucleotide-requiring enzymes from H. influenzae could have a pronounced effect on growth of the organism. Haemophilus malate …
-
Clincal Aspects of Biological Brain Damage Markers
… elevated in CNS infections, for instance in bacterial meningitis. S100B was especially raised in encephalitis. Daily S100B levels did not predict secondary neurological complications or outcome in the neurointensive care unit. Serum GFAP and APC-PCI measurements, prior to neuroimaging, had a …
-
Describing the immune cell profile of ventricular cerebrospinal fluid (CSF) in paediatric central nervous system (CNS) infections
… especially in conditions like tuberculous meningitis (TBM), and these undergo rapid immune cell death after sampling. Consequently, the cell populations in CSF are not well described. Cryopreservation of CSF and flow cytometric analysis have improved the ability to study immune cells in …
Page 1 of 2