Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 161 for “"bacterial infection"”.
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Innate memory to bacterial infection
… markers analysis, cell depletion, heat killed bacterial immunisation and bacterial infection.<br/><br/>This study hypothesised that following immunisation mice would be able to restrain bacterial growth and aimed to investigate the magnitude and longevity and specificity of the response. …
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Study of proteins after recovery from bacterial infection
… on the microglia of mice after recovery from infection is incompletely understood. Microglia cells of mice were collected from two groups, mice infected with BCG vs. control mice (BCG vs. control). The objective of this study was to compare the proteins and peptides present in the microglia of …
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Genetic factors that determine host resistance to bacterial infection
… resistance or susceptibility to bacteria during infection could possibly lead the way in developing new drug targets to stop infection. This thesis focuses on Salmonella enterica serovar typhimurium infection of U937 cells and examines the role the gene SLC7A11 plays in the infection process a …
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Identification and Characterization of Interferon-Stimulated Regulators of Bacterial Infection
… antiviral defense mechanism, yet its role in bacterial pathogenesis remains less well characterized. Using an intracellular pathogen Listeria monocytogenes as a model bacterial pathogen, I sought to identify the roles of individual interferon-stimulated genes in context of bacterial infection. …
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Fic-Mediated AMPylation in Bacterial Infection and Endoplasmic Reticulum Stress
… All currently characterized AMPylators are bacterial in origin and are primarily Type III or Type IV secreted effector proteins, which are injected into a host cell to manipulate host signaling to the microbe's advantage. Examples of these are VopS (Vibrio parahaemolyticus), IbpA …
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Nod1 and Nod2 in Innate Immune Responses, Adaptive Immunity and Bacterial Infection
… the recognition of components derived from the bacterial cell wall, more precisely, moieties of peptidoglycan. As such, Nod1 and Nod2 are implicated in the recognition and the defense against bacterial pathogens. Importantly, the genes encoding these two proteins have also been linked to the …
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Complement Factor H Related Proteins and their Biological Role During Bacterial Infection
… This study demonstrates that CFHR3 binds to the bacterial surface in a fHbp dependent-manner. Furthermore, CFHR3 competes with CFH for binding to fHbp. Bound CFHR3 increases susceptibility of N. meningitidis to complement-mediated lysis which was dependent on the sequence of the fHbp variant. The …
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Relationship of bacterial infection and stress wave travel time in red oak lumber
Anaerobic bacterial infection increases the proclivity of red oak lumber to develop surface, internal and end checks, and develop or aggravate ring failure during drying. It also extends the drying time. Bacterial infection is hard to identify before drying without the use of costly, time- …
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The generation and maintenance of T Helper 17 cells in response to bacterial infection
… factors is in the context of a TH17 inducing infection in vivo. Moreover, studies of the TH17 response have focused mainly on the effector phase and it is currently unclear whether these cells persist into the memory phase. To address these questions, we used mouse models of immunity to the …
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Prevalence and prediction of serious bacterial infection in febrile children: a role for cytokines?
… children at high or low risk of having serious bacterial illness. Knowing the local prevalence of SBI is essential in formulating management strategies because extrapolation from studies done elsewhere is difficult.
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The effect of ovarian hormones upon the susceptibility of the bovine uterus to bacterial infection
Digitized by Kansas State University Libraries
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The investigation of bacterial pathogens of the red macroalga gracilaria gracilis and its response to bacterial infection
… the causes of these collapses is thought to be bacterial disease about which there is very little known. The bacterial pathogens of this macroalga were thus investigated to determine the nature of disease occurrence and how G. gracilis responds to such infections. A large number of culturable …
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Application of a Numerical Method and Optimal Control Theory to a Partial Differential Equation Model for a Bacterial Infection in a Chronic Wound
<p>In this work, we study the application both of optimal control techniques and a numerical method to a system of partial differential equations arising from a problem in wound healing. Optimal control theory is a generalization of calculus of variations, as well as the method of Lagrange …
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REGULATION OF CALCIUM INFLUX AND REACTIVE OXYGEN SPECIES PRODUCTION DURING INFECTION OF LEGUMES BY RHIZOBIA
… of genes required for nodule formation and bacterial infection. In addition NF activates a tip-focused calcium influx, which is less-well studied but is thought to be involved in bacterial infection. NF also activates ROS transient production at the tip of root hair cells. In this thesis I …
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MEMORY TH17 CELLS IN THE LUNG DURING SECONDARY BACTERIAL PNEUMONIA FOLLOWING INFLUENZA A VIRUS INFECTION
Secondary bacterial infection is the primary cause of morbidity and mortality associated with influenza A virus (IAV) infection. Specifically, nontypeable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae (Sp) are the most common cause of lethal secondary bacterial pneumonia in IAV …
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Streptococcus pneumoniae mediated negative regulation of CD8+ T cell effector function
Infection with influenza A virus (IAV) can lead to increased susceptibility to subsequent bacterial infection, often with Streptococcus pneumoniae (Spn). Clinical and experimental data indicate increased disease severity when a coinfecting agent is present during IAV infection, indicating the need …
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Quantitative analysis of TLR-4-mediated cell responses in murine macrophages
TLR-4 is essential in host defense against bacterial infection. By recognition of specific pathogen-associated molecular patterns such as lipopolysaccharide (LPS), TLR-4 can in tandem initiate a pair of downstream signaling pathways to regulate cytokine/chemokine release, endotoxin tolerance and …
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Platelets and their immunomodulatory roles during Streptococcus pyogenes infection
Sepsis and invasive bacterial infection is a major cause of human disease and death worldwide. Streptococcus pyogenes is one of the major pathogens responsible for bacterial infections, which range from mild to severe and life threatening conditions. S. pyogenes contains a cell wall anchored M …
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Synthesis and Characterization of Glycomaterials for Antibacterial Applications
… millions of people contract antibiotic-resistant bacterial infections, and tens of thousands die from infection-related complications in the United States alone. Bacterial infections are one of the leading causes of death worldwide, especially in healthcare institutes such as hospitals and nursing …
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