Global ETD Search
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Showing 1 to 2 of 2 for “"bacterial histidine kinase"”.
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Structural Studies of the Bacterial Histidine Kinases RetS and GacS, Key Components of the Multikinase Network that Controls the Switch Between a Motile Invasive Lifestyle and a Sessile Biofilm Lifestyle in Pseudomonas aeruginosa
… as their primary means of signal transduction. Histidine kinase (HK) and response regulator (RR) proteins comprise these TCSs and phosphorelays. Previously, signal transduction within TCSs and phosphorelays was thought to only occur through a linear series of phosphotransfers between HKs and …
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Structural Basis of Bacterial Transmembrane Signaling
… understood. My research focuses on two distinct bacterial signaling systems: the methyl-accepting chemotaxis protein McpZ in Sinorhizobium meliloti and the signaling histidine kinase GacS in Pseudomonas aeruginosa. What made this work particularly challenging is that the ligands that induce …