Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 34 for “"bacterial biofilm"”.
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Effects of Surface Topography on Bacterial Biofilm Formation
<p>Biofilms are multicellular structures with bacterial cells attached to a surface and embedded in an extracellular matrix. With high-level resistance to antimicrobial agents, biofilms are the cause of chronic infections associated with implanted medical devices such as breast implants, orthopedic …
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Effects of substrate stiffness on bacterial biofilm formation
<p>Biofilms are communities of microbial cells attached on surfaces and embedded in a self-produced extracellular matrix comprised of polysaccharides, DNA, and proteins. Biofilms of pathogenic bacteria cause serious chronic infections due to high tolerance to antibiotics and host immune systems …
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AN INTEGRATED MICROSYSTEM FOR BACTERIAL BIOFILM DETECTION AND TREATMENT
Bacterial biofilms cause severe infections in clinical fields and contamination problems in environmental facilities. Due to the unique complex structure of biofilms that comprise diverse polysaccharides and bacteria, traditional antibiotic therapies require a thousand times higher concentration …
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BACTERIAL BIOFILM FORMATION AS A TOOL TO ASSESS CHEMICALLY TREATED WASTEWATER QUALITY IN DEEP EAST TEXAS
… San Jacinto WWTPs into the environment by using bacterial biofilm formation. <em>Bacillus thuringiensis </em>viable cells at an optical density of 0.03 were used as a model organism, and Nacogdoches city tap water served as a reference for comparison. Microscopy studies confirmed the aggregation …
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Non-invasive assessment of bacterial biofilm in the middle ear using low-coherence interferometry/optical coherence tomography and acoustic measurements
… media (OM) is a middle ear infection caused by bacterial growth between the tympanic membrane (TM) and the inner ear. Children with chronic OM, including OM with effusion and recurrent OM, often have conductive hearing loss and communication difficulties, and need surgical treatment. Recent …
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A bacterial biofilm study: from molecular regulation mechanisms in Escherichia coli to the role of biofilms in mammalian colon cancer development
<p>Biofilm formation is a complex developmental process regulated by multiple environmental signals. In addition to other nutrients, the transition metal iron can also regulate biofilm formation. Iron-dependent regulation of biofilm formation varies by bacterial species, and the exact regulatory …
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In Vitro Evaluation of the Biolase ER,CR:YSGG Side-Firing Tip For Bacterial Biofilm Reduction and Smear Layer Removal in Root-End Cavity Preparation
… are frequently associated with residual bacterial biofilm and smear layer that may remain after conventional chemomechanical debridement and ultrasonic root-end preparation, contributing to post-treatment apical periodontitis and compromising root-end surface cleanliness. The objective of …
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AN EXPERIMENTAL AND NUMERICAL STUDY ON CAVITATION BUBBLE DYNAMICS AND ITS BIOMEDICAL APPLICATIONS
… ultrasound-targeted microbubble disruption of bacterial biofilm are studied. Results identify the interactions between a cavitation bubble and elastic surfaces (beam and sphere), of which the degree of response of these surfaces are found to be dependent to the parameters of the problem such as …
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Biofilm Removal with Acoustic Cavitation and Lavage
<p>Bacterial biofilm colonies attached to orthopedic implants, and surrounding tissues resist to antibiotic treatments, prolong hospitalization, increase mortality, and usually require the removal and replacement of the entire joint. Through acoustic cavitation, it could be possible to remove the …
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Characterizing middle ear reflectance via pole-zero fitting
… Nakajima et al. [2012] and a new study of bacterial biofilm [Nguyen et al., 2013]. Recent measurements were taken using a middle ear acoustic power analyzer (MEPA) system (HearID, Mimosa Acoustics), which makes complex acoustic impedance and reflectance measurements in the ear canal over …
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Comparsion of digestion and particle-associated bacteria after in situ incubation of different barley varieties in the rumen of cattle
… time affected PAB, illustrating that the bacterial biofilm involved in the digestion of grains clearly undergoes compositional shifts during ruminal digestion. Moreover, the digestibility and bacterial biofilm were affected by differences in endosperm structure between corn and barley. …
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Removal of Biofilm through Controlled Cavitation
… consideration towards prevention and removal of bacterial contamination. Bacterial contamination or rather degradation of materials was considered of negligible importance. Bacterial degradation can be serious for long-term manned space mission, more so because there is no way to obtain quick …
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Non-invasive assessment of biofilm growth in the middle ear using a portable low-coherence interferometry system
… almost all chronic OM cases are accompanied by a bacterial biofilm behind the tympanic membrane (eardrum). Biofilms are typically very thin, making them difficult to be recognized using a regular otoscope. However, lowcoherence interferometry (LCI) is capable of detecting and quantifying this …
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Time-of-Flight Secondary Ion Mass Spectrometry Analysis of Microbial Induced Corrosion of Glasses
… of microbes. Improved understanding of relevant bacterial systems and biological secretions help in the development of nuclear waste vitrification materials. A Paenibacillus sp. originating near the Hanford site subsurface was investigated as a model biofilm system. Time-of-flight secondary ion …
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Development of an inhaled liposomal-loaded azithromycin formulation for the treatment of chronic respiratory infection
… with its benefit thought to be due to a dual antibacterial and anti-inflammatory effect. In this thesis, the aim was to develop an inhaled liposomal loaded azithromycin formulation that could be delivered via dry powder inhaler for use in chronic lung infection. By delivering the antibiotic …
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Effectiveness of GentleWave CleanFlow on Multispecies Endodontic Biofilm Removal in Single Rooted Extracted Teeth
… root canal treatment is disinfection. Bacterial biofilms adhere to canal walls and invade the intricate anatomy present within root canal systems. Traditional irrigation methods are unable to deliver irrigation solutions to all parts of the canal system. The GentleWave system is an …
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An investigation of the effects of an antimicrobial peptide on the survival of Acanthamoeba and intracellular bacteria associated with Cystic Fibrosis
… magainin II, was tested against clinical bacterial strains isolated from CF patients and Acanthamoeba. Magainin II has been shown to have antimicrobial efficacy on microorganisms employed in this study. P. aeruginosa, Escerichia coli, methicillin-sensitive Staphylococcus aureus, …
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Microarray-based differential gene expression of listeria monocytogenes cultures grown as biofilms and planktonic cells
… are due to cell cultures forming and growing as biofilms. Biofilm cells are postulated to be more pathogenic than planktonic cells due to the cells forming an exopolymer substance and differentiated strata while working together as a microcommunity. It is thought that Listeria grows as biofilms …
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Impacts of mucins on microbial physiology and interactions
… suppress microbial virulence traits in selected bacterial and fungal opportunistic pathogens and influence the composition of microbial communities. In Chapter 2, I study the impact of mucins on bacterial biofilm formation using the opportunistic pathogen Pseudomonas aeruginosa. I demonstrate …
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Advancing Nanoplasmonics-enabled Regenerative Spatiotemporal Pathogen Monitoring at Bio-interfaces
… multianalyte spatiotemporal monitoring of bacterial biofilm components and pH was demonstrated in in-vitro biofilm models, crucial for wound biofilm diagnostics. Additionally, novel approaches for sensitive virus detection were introduced, including monitoring spectral changes during viral …
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