Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"azacitidine"”.
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Targeting integrin alpha 5 and focal adhesion kinase to overcome azacitidine resistance in higher risk myelodysplastic syndromes
… commonly progressing to acute myeloid leukaemia. Azacitidine (AZA) and decitabine are the only available therapies for higher risk myelodysplastic syndromes shown to improve the overall survival in these patients. However, primary and secondary resistance results in treatment failure in virtually …
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Epigenetic Modulation In Braf Mutated Metastatic Colorectal Cancer
… BRAFV600E mCRC were treated with vemurafenib or azacitidine, alone or in combination, to assess for changes in tumor size. Tumors and cell lines exposed to azacitidine were analyzed for methylation status and for gene expression differences, with particular emphasis on genes identified from the …
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Diet in the promotion or prevention of colorectal cancer
… induced similar levels of DNA damage as 5-azacitidine, suggesting that the model is functional. In conclusion, this work demonstrated the potential of sage tea as a chemopreventive agent and UA and EGCG as compounds with interest for chemopreventive strategies. The AOM in vitro model needs …