Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"automated image analysis"”.
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Budding yeast cell cycle analysis and morphological characterization by automated image analysis
… response as it is related to the cell cycle. The analysis of yeast cell cycle is typically done visually or by using flow cytometry. The first of these methods is slow, while the second offers a limited amount of information about the cell's state. This thesis develops methods for automatically …
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Use of the SSNTD CR-39 and Automated Image Analysis as Applied to Dosimetry for Fast Neutron Therapy
Made available in DSpace on 2017-07-06T18:59:23Z (GMT). No. of bitstreams: 3 Wepprecht_Craig_S_MS.pdf: 22438733 bytes, checksum: 28128907fb138ea8eeeb735694cd8242 (MD5) Wepprecht_Craig_S_MS_ABS.pdf: 464394 bytes, checksum: 7b784505c5f449545a8cb09c5c918196 (MD5) license.txt: 4813 bytes, checksum: …
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One-Shot Learning Model for Cancer Diagnosis from Histopathological Images
… patients are misdiagnosed each year, and several automated image analysis techniques using Deep Neural Networks (DNN) have been proposed for analyzing histopathology images for various cancer types and datasets. Typical challenges for a deep neural network to operate in this setting are limited …
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A feasibility study on using CT image analysis for hardwood log inspection
… and our ability to devise reliable method for automated image interpretation. While a lot of work has gone into demonstrating that certain types of defects manifest themselves in such sensor imagery, there has not been a systematic approach toward making the automatic inspection of logs a …
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Development of an automated system for extraction and quantification of soybean cyst nematode (SCN) eggs and cysts
… such high resolution data. A novel design for an automated SCN extraction system is presented which (1) preserves spatial and temporal information associated with a soil sample, (2) is able to process multiple samples simultaneously using a novel apparatus, and (3) reduces the processing time and …
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Translational perspectives on MSMB and CRISP3 expression and regulation in prostate cancer
… for localized prostate cancer. Using a novel automated image analysis tool, IHC-MARK, we found that MSMB was an independent predictor of recurrence in a large patient cohort. Further, we showed that expression of both MSMB and CRISP3 was induced by androgen in vitro, and MSMB was decreased in …
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Nucleolar dynamics in cellular senescence
… which were subsequently quantitated by automated image analysis. I found enlarged nucleolar area upon the induction of OIS and RS but were not found in secondary senescence. Furthermore, nucleolar expansion was more significant in OIS than RS. In addition to nucleolar hypertrophy, …
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Deep learning for processing histopathology images
… on pathologists, there is a growing need for automated image analysis pipelines that are able to filter out obviously benign samples. However, these algorithms are sensitive to factors of variation such as the staining and scanning conditions with which a tissue specimen is processed that …
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Evaluation of Macrolide-Lincosamide-Streptogramin B Antimicrobial Resistance at Swine Farms
… responsible for MLSB resistance. A robust and automated image analysis method was then developed to quantify FISH signals. The combination of this FISH method with phylogenetic identification protocols allows the quantification of resistance in particular organisms or groups of organisms. Using …
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Bayesian Approaches for the Mechanistic Analysis of Protein Aggregation Kinetics
… drawn. Using Bayesian inference in concert with automated image analysis, I addressed point (i) and investigated how heterogeneity in the fibril population affects their ability to self-replicate. To address point (ii), I developed a novel Bayesian hierarchical model to appropriately treat and …
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Development and Characterization of a Novel Protein Stability Probe
… pipeline to identify regulators of MYC using automated image analysis. This probe enables protein half-life to be scored as a function of fluorescence intensity and distribution. The MYC-Venus probe was piloted by screening a kinase inhibitor library to identify known and novel kinases that …
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Image Processing Algorithms for Diagnostic Analysis of Microcirculation
… in tissue oxygenation and perfusion over time. Automated analysis of this information can be used for real-time diagnostic and therapeutic planning of a number of clinical applications including resuscitation. The objective of this study is to design an automated image processing system to …
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Ultrastructure and function of respiratory cilia in critical illness
… on ciliary survival, assessed using a semi-automated image analysis system. However, the damaging effect of halothane was confirmed and associated with novel findings of decreased amplitude and synchrony, as well as cilia beat frequency (decrease of approximately 30%). In contrast to …
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Diabetes and the Female Heart
… Emission Depletion (STED) microscopy and automated image analysis pipelines to quantify key ECC proteins organisation: transverse tubules (T tubule), ryanodine receptor type 2 (RyR2) clusters, and filamentous actin (F-actin). Results showed that while diabetic rats developed systemic …
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Identification of host factors required for cytosol entry by Shigella flexneri: Results of a genome-wide CRISPR/Cas9 screen
… arrayed high-content microscopy and semi-automated image analysis to confirm a novel set of host factors which facilitate *Shigella* infection. I then established in greater detail the roles of three of the major identified hits, using a further panel of microscopy, flow cytometry and …
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Defining the molecular composition and organisation of Transition fibres in Trypanosoma brucei and their roles in flagellar assembly and length control
… have identified 35 putative TF proteins and used automated image analysis to map their spatial arrangement based on their diameter and offset from the mature basal body. We confirmed the localisation of these proteins at the transition fibre by co-localisation with known transition fibre proteins …
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Time to quit? Non-genetic heterogeneity in cell fate propensity after DNA damage
… probes (Sakaue-Sawano et al., 2008), with semi-automated image analysis to characterise the response of single cells and their descendants to DNA lesions across multiple cell cycle generations. This approach, complemented by generational tracing by flow cytometry, permitted me to characterise …
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Characterizing Trace Element Associations in the Pittsburgh No. 8, Illinois No. 6 and Coalburg Coal Seams
… scanning electron microscopy (SEM) coupled with automated image analysis (AIA) to establish the association between different trace elements and the various components contained in coal. The first step in this analysis required the preparation of 11 different density fractions from a run-of-mine …
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DEVELOPMENT OF A MULTIFUNCTIONAL COOKING APPLIANCE: EVALUATION OF FOOD QUALITY INDEXES AND COOKING FUNCTIONS.
… conventional ovens and dedicated pizza ovens. An automated image analysis method was developed to objectively measure colour changes, enabling precise monitoring of pizza quality during baking. Results showed that high-temperature cooking (450°C) achieved pizzeria-style quality with optimal …
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Temporal biomass density and filamentous bacteria effects on secondary settling
… compared, including the Filament Index ranking, automated image analysis, and manual tracing methods. The filament length/floc area ratio determined by automated and manual methods is a measure that is reliant only on information in microscope images. Filament length/dry solids were determined …
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