Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"autologous chondrocyte"”.
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The role of DEL1 in chondrocyte expansion and mechanotransduction: an investigative study
Matrix-induced autologous chondrocyte implantation offers a potential cure for joint disease and is currently challenged by loss of differentiated phenotype upon culture. To investigate the mechanism of dedifferentiation, chondrocytes were cultured at low density (1x104cell/cm2) and subcultured on …
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Application of endostatin using nonviral gene delivery toward the regeneration of articular cartilage
… cartilaginous constructs in vitro using chondrocytes and mesenchymal stem cells, collagen sponge-like scaffolds and hydrogels, and chondrogenic medium. Peaks in endostatin protein were observed during the first few days of culture, followed by decreases. The endostatin levels were …
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Outcome measurement in articular cartilage repair: exploring the patient perspective
… the evidence base for postoperative care after autologous chondrocyte implantation. The evidence base for postoperative care that was elucidated in this work served to uphold the biomedical model as being the dominant paradigm. Concurrently, the concept of patient-centred medicine was being …
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Cell and tissue engineering of articular cartilage via regulation and alignment of primary chondrocyte using manipulated transforming growth factors and ECM proteins. Effect of transforming growth factor-beta (TGF-¿1, 2 and 3) on the biological regulation and wound repair of chondrocyte monolayers with and without presence of ECM proteins.
… cartilage tissue. Cartilage cell, called chondrocyte is embedded in the matrix (Lacunae) and has round shape in vivo. The in vitro monolayer culture of primary chondrocyte causes morphological change characterized as dedifferentiation. Transforming growth factor-beta (TGF-¿), a cytokine …
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Cell and tissue engineering of articular cartilage via regulation and alignment of primary chondrocyte using manipulated transforming growth factors and ECM proteins. Effect of transforming growth factor-beta (TGF-¿1, 2 and 3) on the biological regulation and wound repair of chondrocyte monolayers with and without presence of ECM proteins.
… cartilage tissue. Cartilage cell, called chondrocyte is embedded in the matrix (Lacunae) and has round shape in vivo. The in vitro monolayer culture of primary chondrocyte causes morphological change characterized as dedifferentiation. Transforming growth factor-beta (TGF-¿), a cytokine …
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A Comparison of the Wear Resistance of Normal, Degenerate, and Repaired Human Articular Cartilage
… osteoarthritic cartilage. One such approach uses Autologous Chondrocyte Implantation (ACI). Dr. Mats Brittberg, and associates at Goteborg University in Sweden began using this cartilage repair procedure in 1987. Other techniques attempt to stimulate the subchondral bone to generate cartilage, …
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Morphologische Untersuchungen von Chondrozyten in dreidimensionaler Hydrogel-Kultur : ein Beitrag zum Tissue Engineering hyalinen Gelenkknorpels
Für die Behandlung von Gelenkknorpeldefekten wird eine große Auswahl an Behandlungsmöglichkeiten beschrieben. Die Autologe Chondrozyten Transplantation (ACT) stellt eine potentielle Therapie dar und ist auf dem Weg, als etablierte Option anerkannt zu werden. Auf den Prinzipien der Periost-covered …
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Radiologic, Histologic and Functional Analysis after Transplantation of Autologous Cultured Chondrocytes into Trachea and Vocal Fold
… a fibrin/hyaluronic acid (HA) composite gel with autologous chondrocytes for tracheal reconstruction. Chondrocytes from autologous rabbit auricular cartilages were expanded and seeded into a culture dish at high density to form stable tracheal cartilages mechanically using a fibrin/HA composite …
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Stem cell matrix and cartilage regeneration
… capacity. Current cell-based therapy using autologous chondrocyte implantation has been developed for decades and promising results have been observed in clinic. However, the shortage of autologous chondrocytes and their uncertain long-term effectiveness have led researchers to find …