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Showing 1 to 2 of 2 for “"autoinducing peptides (AIPs)"”.
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Studies on the Maturation of Secreted Quorum Sensing Peptides That Regulates S. Aureus Virulence
… virulence in the bacterium. Secretion of unique autoinducing peptides (AIPs) and detection of their concentration via AgrC, a transmembrane receptor histidine kinase, coordinates local bacterial population density with global changes in gene expression. In order for S. aureus to produce AIP, …
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Targeting Receptor-Histidine Kinase Signaling in Staphylococcus Aureus
… are known in chemical detail. These ligands (the AIPs) are short (7-9 aminoacyl residue) peptides containing a thiolactone structure, in which the α-carboxyl group of the C-terminal amino acid is linked to the sulfhydryl group of a cysteine, which is always the fifth amino acid from the C-terminus …