Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 78 for “"autofluorescence"”.
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Human skin optical properties and autofluorescence decay dynamics
… in vivo diffuse reflectance spectroscopy, autofluorescence spectroscopy, and temporal behavior of the autofluorescence signal during continuous laser exposure, as well as microscopic in vitro fluorophore distribution and spectral differences. Several interesting physical phenomena were …
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Dynamic imaging of magnetic bioeffects in cells using two-channel two-photon autofluorescence intensity and lifetime microscopy
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2027-05-01
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Development of non-invasive techniques for bladder cancer diagnosis and therapy
… augment bladder cancer detection is the use of autofluorescence spectroscopy. Autofluorescence arises from a number of molecules in human tissue, giving a wealth of structural and metabolic information. Autofluorescence spectroscopy has previously been applied to the detection of a wide range of …
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Early selection of Chinese Hamster Ovary (CHO) cells using simultaneous label-free autofluorescence multi-harmonic (slam) microscopy and Fluorescence Lifetime Imaging Microscopy (FLIM) for biopharmaceutical cell line development
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2027-05-01
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Experimental and Computational Methods for Shortwave Infrared Imaging
… nm) and shortwave infrared (SWIR, 900-1700 nm) autofluorescence imaging. NIR/ SWIR imaging makes use of recently developed, high-sensitivity cameras, and relatively low en-ergy NIR excitation, which is less destructive to and penetrates deeper through biological tissue than conventional …
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Multispectral optical imaging for the detection and delineation of oral neoplasia
… (MDM) acquires in vivo images of oral tissue in autofluorescence, narrow band reflectance, and orthogonal polarized reflectance modes that the diagnostic value of each modality may be qualitatively and quantitatively evaluated alone and in combination. Using in vivo imaging data collected from 56 …
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Molecular Characterization of Human Tissue Samples by Raman Spectroscopy with Different Laser Modes and Excitation Wavelengths
… are compared here. According to this study, autofluorescence and multiple Mie scattering give rise to the high background intensities in the Raman spectra. The reduction in autofluorescence is demonstrated in the comparison between 785 nm multimode (785 MM) and 830 nm multimode (830 MM) …
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LS301 Fluorescence-guided Photodynamic Therapy of brain cancer using PpIX photosensitizer
… tumor delineation using PpIX is limited by autofluorescence and superficial penetration depth. LS301 is a tumor-targeted near-infrared (NIR) contrast agent developed in our lab which allows deeper tumor imaging and avoids autofluorescence. My project aims to investigate whether LS301 can …
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OligoChannel Spectral Analysis in stereotactic laser neurosurgery
… described in this work. The OCSA analyzes the autofluorescence spectrum of each observed tissue point in order to determine its kind. This is possible since autofluorescence spectra of healthy and cancerous tissue show characteristic differences. In contrast to commonly used techniques, the …
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Label-free Optical Approaches for the Non-invasive Assessment of Embryo Quality
… emitted by endogenous molecules, termed autofluorescence. Thus, label-free optical imaging holds great promise for the evaluation of preimplantation embryo quality. In this thesis, I investigated whether optical imaging approaches can non-invasively detect changes in embryos during …
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Ankstyvo gerklų vėžio diagnostika /
… was written, for example „narrow band imaging“, „autofluorescence“ and other methods, reviewed in this thesis, but nevertheless trying to retain 10 years filter. This way, for the purposes of this thesis, 69 publications were selected. Results and conclusions: diagnostic methods used for early …
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Flow Cytometric Analysis for Cyanobacteria in 36 New Jersey Freshwater Bodies
… as part of the phycobillisome that allow autofluorescence. In this study, 36 freshwater bodies from 14 New Jersey counties were collected and processed for flow cytometric analysis for forward- scatter, phcyoerthrin and allophycocyanin parameters. Pure cultures of <em>Synechococcus</em> …
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Novel Design Strategies For Engineering Biliverdin-Binding Fluorescent Proteins
… systems. However, poor penetration and high autofluorescence of visible light in mammalian tissue has motivated the design of FPs that can take advantage of the minimal autofluorescence, scattering, and absorption in the near-infrared (NIR) “optical window” (650-900nm). Genetically-encoded …
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Quantifying passive drug transport across lipid membranes
… drug molecules are tracked directly using their autofluorescence in the ultraviolet. The permeability coefficient of the drug is inferred by studying the increase in drug autofluorescence intensity within vesicles as they traverse a microfluidic network while exposed to the drug for well defined …
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Advancing Dynamic Imaging for Microfluidic Stimulated Tissues: Biology, Techniques, and Applications
… changes in electron transfer flavoprotein (ETF) autofluorescence to fatty acid oxidation in living pancreatic islets. We found that elevated glucose (>10 mM) decreases the ETF redox state within 20 minutes in islets when presented with a mixed nutrient condition associated with glucolipotoxicity. …
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Development of Multi-Modality Imaging Cart for Barrett’s Esophagus
… by using a multi-modal imaging system combining autofluorescence spectroscopy, optical coherence tomography, and diffuse reflectance spectroscopy to perform label-free optical biopsies on ex-vivo tissue. These images will be co-registered and validated with histological biomarkers for BE. The …
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Fluorescent materials for short-wave infrared imaging
… and benefits from a general lack of tissue autofluorescence.
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Fluorescence endoscopic imaging system for detection of colonic adenomas
Background/Aims: Autofluorescence spectra have been collected from colonic mucosa with optical fiber contact probes. This technique was found to be sensitive to the biochemical and microarchitectural differences between normal and pre-malignant tissue. It is desired to extend this method to wide …
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Development and Evaluation of Whole Slide Hyperspectral Confocal Fluorescence and Brightfield Macroscopy
… microscopy is the high background due to the autofluorescence (AF) of endogenous compounds within cells and tissues. Often, AF can prevent the detection and/or accurate quantification in fluorescently- labelled tissues and, in general, can reduce the reliability of results obtained from such …
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