Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"auditory brainstem response"”.
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Auditory brainstem response latency in noise as a marker of cochlear synaptopathy
… is thought to arise from central sites of the auditory system with the assumption that sound encoding at the auditory nerve (AN) is robust. Despite this assumption, growing evidence from animal and human studies suggests that acoustic exposure, too modest to elevate hearing thresholds, can …
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The education programmes and perceived competence in using auditory brainstem response testing : the audiologists' perspective
Includes bibliographical references (leaves 84-93).
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A multiple test battery approach during the assessment of the auditory nervous system of patients with multiple sclerosis
… many studies illustrated some degree of auditory involvement associated with this disease. The auditory brainstem response has dominated the field during the assessment of the auditory system of patients with Multiple Sclerosis. Although this objective test procedure is useful during the …
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Development of Auditory Sensitivity in Barn Owls (Tyto furcata pratincola)
… 12 kHz) and clicks of different rates (5-90 Hz). Auditory evoked potentials (AEPs) of the auditory nerve were recorded using the auditory brainstem response (ABR). Barn owl hearing matured in a similar trend to other developing vertebrates, including kittens, budgerigars, chickens, and gerbils. …
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Responses from electric stimulation of cochlear nucleus
… nucleus (CN), the exclusive destination of the auditory nerve, is the gateway for all central processing of auditory information. The CN comprises three major subdivisions: anteroventral, posteroventral and dorsal (AVCN, PVCN and DCN, respectively), each of which contains anatomically and …
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Investigation of acquired hearing loss in dopamine beta hydroxylase (DBH)-mutant mice
… susceptible to middle-ear disease. We measured auditory brainstem response (ABR) and distortion-product otoacoustic emission (DPOAE) thresholds, as well as sound-induced umbo velocity, and used standard histological techniques to study normal and pathological middle-ear anatomy. Anatomical …
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Noise-induced cochlear neuronal degeneration and its role in hyperacusis -- and tinnitus-like behavior
… neuronal degeneration results in abnormal auditory behavior, indexed by the acoustic startle response and prepulse inhibition (PPI) of startle. Responses to tones and to broadband noise were measured in mice exposed either to a neuropathic exposure causing primary neuronal degeneration, or …
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Development of a non-invasive electrophysiological system for measuring the auditory capability of marine animals
… neurological system to definitively profile the auditory responses of aquatic animals, presented as audiograms showing hearing threshold verses sound frequency. The accuracy of such information is essential for the optimisation of bio-technical devices such as the Acoustic Fish Deterrent (AFD) …
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Mutation of SLC7A14 Causes Syndromic Hearing Loss
… bundles and IHC loss throughout the cochlea. Auditory brainstem response (ABR) thresholds were elevated in Slc7a14-knockout mice, indicative of progressive hearing loss. However, distortion product otoacoustic emission (DPOAE) measurements showed normal OHC function in wildtype and knockout …
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Cochlear neuropathy : detection using envelope following responses and Impacts on central auditory coding
… acoustic environment is conveyed to the brain by auditory nerve (AN) fibers. While essential for hearing, these fibers may also be the most vulnerable link in the auditory pathway: moderate noise exposure can cause loss of AN fibers without causing hair cell damage or permanent threshold shift. …
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An in vivo study of GTF2IRD1 function and its contribution to the physical features of Williams Beuren Syndrome
… knockout mice was carried out by examining the auditory brainstem response (ABR) and the distortion product of otoacoustic emissions (DPOAE). The role of GTF2IRD1 in the development of facial skin was examined by a detailed investigation of the control of epidermal proliferation, differentiation …
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Clinical and Molecular Characterization of Auditory Neuropathy
Auditory Neuropathy (AN) is diagnosed when the auditory brainstem response (ABR) is absent and outer hair cells (OHC) function normally, which indicates that the lesion lies in the inner hair cells (IHC), their afferent nerve’s synapse or the auditory nerve. While the presence of non-syndromic …
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Development of Cochlear Nonlinearities in Normal and Tshr Mutant Mice
… To accomplish these goals, the development of auditory function was studied in both normal mice (BALB/c) and a strain commonly referred to as the hyt, or Tshr mouse. The Tshr mouse expresses a naturally occurring point mutation in the gene that encodes the thyrotropin receptor resulting in the …
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Primary neuronal degeneration in the guinea pig effects on spontaneous rate-type
… cell recovery; suprathreshold amplitudes of the auditory brainstem response remained attenuated for high-frequency stimuli, consistent with primary neural degeneration in the basal half of the cochlea. Single-fiber recordings from exposed animals showed that all sound-evoked response properties, …
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Blast-Induced Tinnitus: A Combined Behavioral, Memri, And Electrophysiology Study
… <p>Tinnitus and hearing loss are the frequent auditory-related co-morbidities of blast trauma. The etiology of blast-induced tinnitus is also muddled by brain mechanisms associated with emotional and cognitive problems such as anxiety, memory loss, and depression. We set out to develop a …
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Investigation of the Function of the Olivocochlear Efferent Nerve Pathway in Humans
… nerve pathway descending from the region of the brainstem surrounding the medial portion of the superior olivary complex, and called the medial olivocochlear pathway. Previous research has demonstrated that activation of this pathway is associated with changes in cochlear micromechanics, and …
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Tinnitus and Decreased Subcortical and Cortical Inhibition
… reduction in inhibitory function in the central auditory nervous system. Evidence, primarily from invasive studies of animal models of tinnitus, indicates that these changes occur at both the subcortical and cortical level. Auditory evoked potential (AEP) indices of subcortical inhibition …
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Cochlear Sensitization to Aminoglycosides: Defining the Role of JAK-STAT Signaling
… to kanamycin. These effects included worsened auditory brainstem response thresholds, reduced suprathreshold neural output, impaired outer hair cell-dependent cochlear amplification, and expanded physiologic injury. To localize the effect genetically, Jak2 was conditionally deleted in …
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Understanding Hearing Loss in Osteogenesis Imperfecta
… X-ray fluorescence microscopy, and auditory brainstem response tests.</p> <p>Our findings show that while <em>oim/oim</em> ossicles show no alterations in tissue mechanics, composition and collagen fibers organization, they are brittle at the organ level, with thin regions of the …
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