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Showing 1 to 20 of 31 for “"atrial natriuretic"”.
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Atrial natriuretic peptide
Contains fulltext : mmubn000001_08730127x.pdf (Publisher’s version ) (Open Access)
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Endogenous atrial natriuretic factor and airway control
… experiments investigating the role of endogenous atrial natriuretic factor (ANF) in the modulation of airway calibre and bronchial hyperresponsiveness in humans under normal physiological conditions. Two approaches are used. One approach examines the diurnal variation of endogenous ANF and its …
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Expression of atrial natriuretic factor in transgenic potatoes
… the expression of the precursor molecule of rat atrial natriuretic factor, ANF-(1-126), in transgenic potatoes (Solanum tuberosum L. cultivar Iwa). Four ANF gene fusions were constructed for extracellular expression of ANF-(1-126) either by retaining the native signal peptide of ANF or replacing …
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Atrial natriuretic peptide and streptozotocin-induced diabetes in rats
… undertaken to determine whether immunoreactive atrial natriuretic peptide (irANP) concentrations in plasma and atrial tissue are altered in experimental diabetes mellitus (DM), and to compare the response of the DM and normal groups to exogenous administration of ANP. OM was induced by …
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Studies of atrial natriuretic peptide in the freshwater turtle Pseudemys scripta
Attempts to purify further the active component using reversed-phase HPLC techniques and the radio-receptor assay resulted in the isolation and sequencing of two ANP receptor-binding peptides. These peptides were not homologous to ANP but rather were homologous to the muscle protein fragments …
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Prevention of Ischemia-Reperfusion Injury in the Rat Liver by Atrial Natriuretic Peptide
This work characterizes the protective effects of ANP preconditioning in ischemia-reperfusion injury of the isolated perfused rat liver. It was of particular interest to evaluate the influence of ANP on the mode of cell death occurring during cold ischemia and reperfusion and to elucidate the …
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Influence of the Atrial Natriuretic Peptide on TNF- αα α -activated human endothelial cells
The present work deals with the inhibitory action of ANP on TNF- -induced expression of adhesion molecules (ICAM-1, VCAM-1, E-selectin), chemokines (MCP-1), and cytoskeleton changes in human endothelial cells. 5.1.1 Effect of ANP on TNF- α αα-induced CAM expression The following diagram shows a …
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Characterisation of Anti-Apoptotic Signalling Pathways in Hepatocytes activated by alpha-Lipoic Acid and Atrial Natriuretic Peptide
… alpha-lipoic acid (R-LA) and the hormone atrial natriuretic peptide (ANP) are known to exert potent hepatoprotective action. The present work characterises alpha-lipoic acid- and ANP-mediated signal transduction pathways involved in the regulation of apoptotic cell death in two different …
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Einfluss von vascular endothelial growth factor, transforming growth factor-beta-1, Interleukin-6, atrial natriuretic beptide, brain natriuretic peptide und Cortisol auf die Gen-Expression des menschlichen Herzmuskels in vitro
… Factor-beta-1(TGF-beta-1), Interleukin-6 (IL-6), Atrial Natriuretic Peptide (ANP), Brain Natriuretic Peptide (BNP) und Cortisol (bzw. Dexamethason) auf das humane Myokard. Um Rückschlüsse auf mögliche Hypertrophie induzierende bzw. Hypertrophie inhibierende Effekte zu erlangen, wurde die …
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Regulation of the Nuclear Factor of Activated T Cell (NFAT) Family of Transcription Factors in the Freeze Tolerant Wood Frog, Rana sylvatica
… activated NFATc4 in liver, leading to increased atrial natriuretic peptide levels. Neither freezing nor anoxia significantly affected NFATs in skeletal muscle. Overall, the study indicates that NFATs have a crucial role to play in the natural cryoprotection of liver.
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Physiological and cellular characterization of a plant natriuretic peptide
… is recognized by antibodies against vertebrate atrial natriuretic peptides (ANPs). It has been demonstrated that a recombinant Arabidopsis thaliana natriuretic peptide analogue (AtPNP-A) molecule can induce osmoticumdependent water uptake into protoplast at nanomolar concentrations thus …
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Molecular Characterisation of the Brassinosteroid, Phytosulfokine and cGMP-dependent Responses in Arabidopsis thaliana
… organisation that is not dissimilar to that of atrial natriuretic peptide receptors NPR1 and NPR2. The findings also strongly suggest that cGMP has a role as a second messenger in both Brassinosteroid and Phytosulfokine signalling. We speculate that other proteins with similar domain …
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Investigations into the influence and role of tissue factor in the pathogenesis of myocardial hypertrophy
… of the cells with TF alone up-regulated atrial natriuretic factor (ANF) expression, whilst the presence of the TF-associated proteases, factor VIla and factor Xa, suppressed this effect, suggesting that contact between TF and blood within the heart can exacerbates the hypertrophic …
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Manipulation of second messengers by ectopic expression of receptors in transgenic Drosophila
… constructed or obtained transgenic for the rat atrial natriuretic peptide receptor, GC-A, the Drosophila 5HT7Dro receptor, and the Drosophila 5HT1ADro receptor, under control of the UAS or heat-shock promoter. Tubules dissected from such flies were then demonstrated to show diuresis induced by …
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Plant natriuretic peptides - elucidation of the mechanisms of action
… by antibodies generated against vertebrate atrial natriuretic peptides (ANPs). Functional characterization of these immunoanalogues, referred to as immunoreactive plant natriuretic peptides (irPNPs) or plant natriuretic peptides (PNPs), has shown that they play important roles in a number of …
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Regulation of natriuretic peptide system activation:effects of spontaneous natriuretic peptide mutations and identification of novel natriuretic peptide receptor phosphorylation sites.
… that mediate the physiologic effects of natriuretic peptides, including reduction of blood pressure and blood volume, stimulation of long bone growth, and regulation of cardiac size. Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) signal through GC-A while C-type …
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Fluid retention in congestive heart failure-the role of natriuretic peptides and arginine vasopressin
… heart failure (CHF). The role played by atrial natriuretic factor (ANF), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP) and arginine vasopressin (AVP) in CHF is not fully understood. Studies were done in 300days old male normal and cardiomyopathic hamsters with moderate …
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Bestimmung von "Brain Natriuretic Peptide"(BNP) bei gesunden Hunden
… natriuretischen Peptide gehören drei Peptide: Atrial Natriuretic Peptide (ANP), Brain Natriuretic Peptide (BNP) und C-type Natriuretic Peptide (CNP). BNP wurde ursprünglich im Gehirn von Schweinen isoliert, bald stellte sich heraus, dass eine wesentlich höhere Konzentration im Herz vorliegt. …
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Molecular mapping of the rabbit atrioventricular node
… for the important conduction delay between atrial systole and ventricular systole. The anatomical architecture and functional properties of the AVN are complex. Ionic currents have been characterised in the AVN at both the whole tissue level and single cell level. However, little is known …
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