Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 54 for “"atopic dermatitis"”.
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The Lothian atopic dermatitis study
Atopic dermatitis is a chronic, debilitating skin disease. Children have occupied the major part of investigators' time, but cross-sectional community studies, encompassing the whole population, are lacking. This thesis describes an epidemiological study, based on a general practice of 9,786, and …
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Improving the skin barrier function in atopic dermatitis
Atopic dermatitis, AD (synonym eczema) is a chronic inflammatory skin disease. It affects between 10 to 20% of children and 1 to 3% of adults worldwide. It is an important cause of morbidity and is estimated to cost £465 million per annum to the UK. AD is part of a family of Th-2 driven diseases …
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Determinants of systemic treatment response in atopic dermatitis
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intense pruritus and recurrent eczema. Its heterogeneous pathophysiology involves epidermal barrier dysfunction, immune dysregulation, and alterations of the skin microbiome. Despite major advances through targeted …
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A systematic review of treatments for atopic dermatitis
Atopic dermatitis is a very common inflammatory skin disease, particularly in children. A systematic review of randomised controlled trials of treatments for atopic dermatitis (AD) was carried out to assess how many trials exist, what they cover, what they do not cover, the research gaps, provide a …
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The skin microbiome in health and atopic dermatitis
… the SMGC, we investigated the skin microbiome in atopic dermatitis, a prevalent inflammatory skin condition characterized by recurring episodes of red, itchy, and swollen skin. Atopic dermatitis flares have been associated with the proliferation of various staphylococcal species, with only <i>S. …
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ROLE OF MICRORNAS IN THE PATHOGENESIS OF ATOPIC DERMATITIS
Atopic dermatitis (AD) is a common inflammatory skin disease, which is characterized by skin barrier defect and immune dysregulation. In this study, we investigated the role of microRNA in AD pathogenesis. We found miR-335 to be highly expressed in the differentiating layers of normal epidermis but …
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Relationship between family histories and allergic disease with childhood atopic Dermatitis
… history of allergic disease and children's atopic dermatitis. Data from the 2011 Research on the Current Status of Atopic Disease with Elementary Schools and Kindergartens in Suwon were used for analysis. Among 20,052 persons agreeing to the survey 18,943 Subjects who had answer about …
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The Clinical Significance of Fungal Allergy in Patients with Atopic Dermatitis
… 중증도 지표인 standardized clinical scoring system for atopic dermatitis (SCORAD) 지수를 이용하여 평가하였다. 알레르겐 특이 IgE 항체가 3.5kU/L(CAP class 3)이상인 경우, 그 알레르겐에 대해 유의한 알레르기를 보이는 것(감작상태)으로 판정하였다. 아토피피부염 환자들에서 특정 알레르겐에 대한 감작률은 D. farinae 65.0 %, D. pteronyssinus 63.5%, M. furfur 50.9%, C. albicans 38.2% 그리고 …
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Developing druggable in vitro models for investigating itch in atopic dermatitis
… from itchy skin. Among participants affected by atopic dermatitis (AD, 6%), a relapse-remitting, inflammatory skin disease, 96.8% complained about chronic itch, making it a hallmark symptom. Some forms of itch (e.g., histaminergic, resulting from an insect bite) are well-understood and treatable, …
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Effects of parenting experiences and early maladaptive schemas on adjustment to atopic dermatitis
Atopic dermatitis (eczema) is a psychosomatic chronic skin condition. Onset of the condition usually occurs in early life. Some people however, do develop it much later. Even though studies have demonstrated high levels of psychological disturbance and maladjustment among most people with AD, some …
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Environmental factors associated with atopic dermatitis in children in urban and rural South Africa
… contribute to the high prevalence of childhood atopic dermatitis (AD). Objectives: To identify environmental exposures associated with AD in children living in three residential areas of South Africa. Methods: A total of 3144 children aged 3 to 11 years participated in 1999 in a cross-sectional …
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Bacteriome interactions in pediatric atopic dermatitis in a rural and urban South African cohort
… bacterial dysbiosis is common in children with atopic dermatitis (AD). However, there is limited data of these bacterial changes in sub-Saharan children with AD. Therefore, this study investigated the bacterial alterations in skin and nasal bacterial communities in AD compared to healthy …
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Improving the self-management of atopic dermatitis: the efficacy of a pictorial patient education tool
Background: Atopic dermatitis (AD) is a chronic relapsing skin condition that requires persistent self-management. Patient education is a key component in the self-management of many chronic diseases as it facilitates disease understanding and patient empowerment. Objective: The purpose of this …
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Barrier disruption in STAT6VT transgenic mice as a potential model for atopic dermatitis skin inflammation
Atopic dermatitis (AD) is a pruritic, chronic inflammatory skin disease with a lifetime prevalence of 10-20% in children and 1-3% in adults, worldwide. In the past three decades, prevalence of the disease has increased by two to three-fold in industrialized countries, with higher incidences in …
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Intrinsic alterations of the skin barrier function promote the pathogenesis of atopic dermatitis in dogs
Canine atopic dermatitis (cAD) is a chronic inflammatory skin disease affecting up to 10% of the canine population, it is the second most common allergic disease in dogs. Canine AD has many similarities to human AD and for this reason the dog has been suggested to be a good animal model to study AD …
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Investigating role of IL-4 receptor alpha (IL-4Ra) in murine models of atopic dermatitis
Atopic dermatitis (AD) is a common pruritic inflammatory skin disease with complex environmental and genetic predisposition factors. Primary skin barrier dysfunction and aberrant T helper 2 (TH2) responses to common allergens, together with increased serum IgE antibodies, characterise the disease. …
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The role of Interleukin-4 induced gene 1 (IL-4i1) in allergic asthma and atopic dermatitis
… known as allergens. Both allergic asthma and atopic dermatitis (AD) are said to be induced by elevated levels of immunoglobulin E (IgE) and T helper 2 (Th2) immune cells and inflammatory associated cells such as eosinophils, mast, and basophils. Globally, asthma is affecting more than 300 …
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