Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"asymmetric localization"”.
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Asymmetric localization of prospero and numb specifies cell fates in the Drosophila CNS
… in sibling cells. The numb protein is asymmetrically localized to the cortex of dividing precursor cells in the Drosophila central and peripheral nervous systems. numb is then segregated into only one of the progeny cells where it is necessary and sufficient to autonomously specify that …
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Local Wnt11 Signalling and its role in coordinating cell behaviour in zebrafish embryos
… is still unclear. While in Drosophila, the asymmetric localization of PCP components is crucial for the establishment of cell polarity, no asymmetric localization of Wnt11 pathway components have so far been observed in vertebrates. To shed light on the cellular and molecular mechanisms …
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Mechanisms of Asymmetric Protein Localization in Drosophila Embryonic Neural Stem Cells
… is dependent on Dlg's apically enriched localization. Pharmacological studies suggest Lgl mediated basal targeting occur via a myosin-based transport mechanism, which is supported by genetic studies that show loss of Myosin II suppresses Lgl phenotype in neuroblasts. Taken together, we …
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Function and Regulation of the Cell Fate Determinant Numb in Polarized Epithelial Cells
… was originally identified in Drosophila as an asymmetrically localized cell fate determinant, and was subsequently found to be conserved in vertebrates. In mammalian polarized epithelial cells, Numb is distributed asymmetrically along the basolateral membrane domain. The work herein describes …
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Cell Size Control And Asymmetric Cell Fates In Start Of The Saccharomyces cerevisiae Cell Cycle
… Ace2 and Ash1. This work demonstrates how asymmetric localization of cell-fate determinants results in cell-type-specific regulation of the cell cycle in budding yeast.</p>