Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"astroglioma"”.
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Roles of the P2X7 receptor in C6 astroglioma: in vitro and in vivo studies
The purinergic P2X7 receptor (P2X7R) is an ionotropic adenosine triphosphate(ATP) receptor which is closely linked with pathological conditions in the central nervous system (CNS). Gliomas are the most common primary brain tumors with presently no cures. The roles of the P2X7R in these diseases …
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The Impact of Melanocortin Receptor Ligands on Astrocyte Signalling and Metabolism
… mouse primary cortical astrocytes and the human astroglioma cell line U373. The findings of this thesis indicate that MCRs are expressed in both cell models examined. Pharmacological modulation of MCRs led to increased ERK1/2 phosphorylation and enhanced cell metabolism in the human U373 …
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Repulsive cues and signalling cascades of the axon growth cone
The aim of the work described in this thesis is to investigate the nature and mechanisms of action of repellent cues for growing axons. In particular I try to resolve the controversy in the literature regarding the need for protein synthesis in the growth cone in response to external guidance cues. …