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Showing 1 to 2 of 2 for “"assembly compartment"”.
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Characterisation of Novel Autophagy and Necroptosis Antagonists Encoded by Human Cytomegalovirus
… thereby delaying the formation of the virion assembly compartment and reducing viral replication. Necroptosis, another key intrinsic antiviral defence, eliminates infected cells by inducing lytic cell death and thereby preventing viral dissemination. Only two HCMV-encoded necroptosis …
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The Roles Of Human Cytomegalovirus Tegument Proteins Pul48 And Pul103 During Lytic Infection
… producing factory, termed the cytoplasmic virion assembly complex (cVAC). Generating drugs that affect cVAC development or function provides an alternative mode of action for HCMV antivirals that can essentially eliminate virion production. The objective of this work is aimed at identifying …