Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 5146 for “"assay"”.
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MULTIPLEX ASSAY DESIGN
This thesis explores the design of assays for the multiplexed detection of various infectious diseases. A single-pot, 8-plex end-point PCR reaction for the detection of carbapenemase-producing Enterobacteriaceae (CPE), vancomycin-resistant Enterococcus (VRE) and colistin resistance has been …
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Assay procedures for dehydroepiandrosterone
<p>Dehydroepiandrosterone (DHEA) is a 17-ketosteroid which is produced by the adrenal cortex and is excreted in the urine as DHEAsulfate, In diseases of the adrenal cortex, such as adrenal carcinoma or adrenal hyperactivity, the level of DHEA-sulfate in the urine is increased. There are two …
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Advancements in nuclear waste assay
… of the practice of the non-destructive gamma-ray assay of nuclear waste containers. A number of potentially accuracy-limiting issues were identified and addressed, resulting in new developments which were implemented on an instrument prior to entering it into service. A set of Pu reference sources …
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Assay Development for Tau-directed Therapeutics
… induce disease-relevant aggregates and develop assays to screen therapeutics, this study explores mechanical shaking-induced aggregation and RNA-induced aggregation, as well as the effect of a commonly observed post-translational modification in NFTs, hyperphosphorylation, on tau aggregation. We …
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Assay and Purification of Coxsackievirus B3
… The procedure. Quantitative methods for the assay and purification of CB3 were developed. CB3 was propagated in buffalo green monkey (BGM) cells in tissue culture. The virus was released from the infected BGM cells by various methods. Purification methods included precipitations, …
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Insulin: its assay, extraction and sources
In May 1992, Banting and Best, working in the Physiology Department of the University of Toronto, obtained the first active extracts from pancreas. The credit for the preparation of such extracts capable of effecting a lowering of the blood and urinary sugar, and serviceable in mitigating the …
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Aligning heterogenous single cell assay datasets
… development of a number of different single-cell assays, datasets that collect multiple types of assays on the same cells are rare. In this thesis, we explore the ability of three methods to integrate datasets from different single-cell assays based on an existing paired single-cell dataset of …
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Fluorescence assay for polymerase arrival rates
To engineer complex synthetic biological systems will require modular design, assembly, and characterization strategies. The RNA polymerase arrival rate (PAR) is defined to be the rate that RNA polymerases arrive at a specified location on the DNA. Designing and characterizing biological modules in …
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Novel strategies for DNA detection and assay.
… aimed at developing new strategies for DNA bioassays, using alternative detection techniques and new labelling methods. Firstly, a new labelling technique for DNA sequencing was developed using lanthanide chelates. These compounds were identified as likely candidates to replace traditional dyes …
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Assay for Rifampicin Resistant M13 RF Synthesis
<p>We have developed a rapid assay which can detect the function of the origin of 0X174 complementary strand DNA in Ml3 by virtue of its ability to initiate the synthesis of M13 complementary strands in the presence of the antibiotic rifampicin. A segment of DNA carrying the sequence recognized by …
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Enzyme-linked immunosorbent assay for herbicide detection
… to be used in an enzyme linked immunosorbent assay (ELISA) for herbicide detection in soil.
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A new volumetric assay for lead ores
Thesis: B.S., Massachusetts Institute of Technology, Department of Chemistry, 1870
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Development and Standardization of a Short-Term Assay for Evaluating Polluted Estuarine and Coastal Environments: The Medaka Embryo-Larval Assay
… of studies to develop a routine, standardized assay which can assess the acute and sublethal impacts of individual toxicants and complex mixtures. The eggs of this Cyprinodont minnow were topically treated with each toxicant or mixture dissolved in membrane permeable dimethylsulfoxide (DMSO) …
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An enzyme-linked immunosorbent assay (ELISA) for endotoxins
Typescript (photocopy).
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An enzyme-linked immunosorbent assay (ELISA) for endotoxins
Typescript (photocopy).
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A continuous spectrophotometric assay for phosphate releasing enzymes
A new continuous coupled UV-spectrophotometric assay is described for two phosphate releasing enzymes, aspartate transcarbamylase and ATPase of Herpes Simplex Virus. Phosphate release is coupled to the phosphorolysis of the nucleoside analogue 7-methylinosine catalyzed by purine nucleoside …
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Microseparation Strategies for the Assay of Neuronal Samples
The HPLC research presented here represents our first attempt to use microbore HPLC in the analysis of peptides from an identified cluster of neurons. It involves downscaling HPLC to work with smaller samples to follow the biochemistry of the neurons. Results described here are the culmination of …
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