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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 143 for “"aspartic"”.
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Inactivation of Aspartic-Transcarbamylase in Sporulating Bacillus Subtilis
Made available in DSpace on 2014-12-10T23:24:35Z (GMT). No. of bitstreams: 1 7414635.pdf: 4743120 bytes, checksum: 99fd6b64f91057d416ad314f517284d9 (MD5) Previous issue date: 1974
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A study of the platinum (II), palladium (II), and rhodium (III) chelates of aspartic and glutamic acid
… of two alpha-animo dicarboxylic acids, namely aspartic and glutamic acids. The metal ion upon which the investigation is focused are platinum (II), palladium (II), and rhodium (III). Several of these are reported as having been repaired. The series is incomplete, however, and little study has …
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FTIR study of carboxylic acids and tyrosines in bacteriorhodopsin
… of single amino acids during the photoreaction. Aspartic acids and glutamic acids in bR were monitored by 13C labeling. Tyrosines were monitored by both 2H and nitrate substitution. Some of the amino acid band regions were decomposed by curve fitting. Alteration of absorption bands among …
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I.~Design, Synthesis, and Evaluation of a Rigidly Constrained Peptidomimetic as a Potential Type I Beta-Turn. II.~Development of Novel Estrogen Receptor Ligands With Unique Endocrine Profiles. III.~Design, Synthesis and Biological Evaluation of Potential Aspartic Protease Inhibitors Based on the Diaziridine and Diazirine Isostere
We have prepared novel aspartic proteases inhibitors based on the diaziridine and diazirine isostere, as potential transition-state mimics of the tetrahedral intermediate found along the reaction pathway for enzyme mediated peptide bond hydrolysis. These isosteres (143 and 144) have been …
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Influence of additives on stabilization and mineralization pathway of amorphous calcium carbonate nanoparticles
… The influence of organic additives (glucose, aspartic acid, glutamic acid) and Ca2+ on the mineralization and stabilization of PAA-ACC nanoparticles was investigated by measuring the size of the nanoparticles as a function of time using Dynamic Light Scattering (DLS); the adsorption of organic …
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The Synthesis of Amphiphilic Glycolipids as Potential Inhibitors of Bacterial Adhesion
… thesis. A variety of glycolipids based around an aspartic acid, aliphatic or aromatic scaffold were investigated. Chapter 1 describes the biological importance of glycolipids and how they can be utilised as anti-adhesion agents and immunomodulators. The concept of multivalency is also discussed, …
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Análisis de un proceso de ultrafiltración extractiva de aminoácidos utilizando contactores de fibras huecas
… the recovery of amino acids (phenylglycine and aspartic acid) from dilute aqueous solutions has been investigated in the present work. The membrane assisted liquid extraction is a hybrid process which allows the integration in only one unit of the two steps involved in liquid-liquid extraction. …
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AMP Deaminase 3 overexpression regulates cellular energetics and signaling for PGC-1α activation.
… 4.8-fold) and ULK1 (Ser555, 2-fold) (p<0.001). Aspartic acid levels increased 7.1-fold (p<0.001), suggesting decreased activity of the purine nucleotide cycle (IMP + aspartic acid [rightwards arrow][rightwards arrow] AMP). As expected, myotubes that were overexpressing AMPD3 had significantly …
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Characterization of Leucyl -Trna Synthetase From Homo Sapiens and Escherichia Coli in Aminoacylation, Amino Acid Editing and Interdomain Interactions
… discriminator and universally conserved aspartic acid that were mutationally characterized. Substitution of threonine to alanine uncoupled specificity similar to other LeuRSs. However, the introduction of bulky residues in the amino acid binding pocket failed to block deacylation of tRNA, …
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Molecular studies of peptides at solid-liquid interfaces
… model peptide (consisting of diblock units of aspartic acid and isoleucine residues) adsorbed at a charged model surface (consisting of CH₂ atoms) in vacuum, and in presence of various solvent compositions (by addition of cosolvents) to study the conformational and orientational aspects of …
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The synthesis and pharmacological evaluation of quisqualic acid and some novel excitatory amino acid mimetics
L-Glutamic acid and L-aspartic acid are believed to be the principal initiators of excitatory synaptic neurotransmission in the mammalian central system. A number of molecules of either natural or synthetic origin have been identified as possessing agonist or antagonist properties at glutamate …
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The Effects of Nitrogenous Compounds on Decay of Wood by Soft-Rot Fungi
… and cellulase production in the presence of aspartic acid and glutamic acid, the two amino acids found to be most abundant in the sapwood of timbers investigated. A humidity chamber technique was employed to study soft-rot decay of wood. This enabled pure fungal cultures to be used to …
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Investigating the biosynthesis of fosfazinomycin
… studies revealed that the primary amine from aspartic acid is incorporated into the phosphonohydrazine moiety of fosfazinomycin. Further purification and spectroscopic efforts additionally demonstrated that the nitrogen atom originating from aspartic acid is donated to the site proximal to the …
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Triggerable ligand presentation using caged-RGD
… that present a UV-labile caged-Arginine-Glycine-Aspartic Acid (RGD) ligand and evaluate the effects on cell activities. RGD is the minimal adhesive sequence of fibronectin. By dynamically modulating adhesive ligand presentation, the effects of temporal control on cell processes can be elucidated. …
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Synthetic Alkyl Glycolipids as Therapeutic Agents: Their Synthesis as Potential iNKT Cell Stimulators and their Anti- Microbial Properties
… cell stimulatory ligands. Simple glycolipids, L-aspartic acid based glycolipids, glycoglycerolipids and L-serine based glycolipids were explored. Simple galactosyl glycolipids containing O- and N-glycosidic linkages and L-aspartic acid based glycolipids were constructed as in Chapter 2 with a …
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Self Assembling Bioactive Materials for Cell Adhesion in Tissue Repair
… zwitterionic 2nd generation dendrons based on aspartic acid do not. Incorporation of the well known arginine-glycine-aspartic acid (RGD) sequence, which is found in many adhesive proteins, to the dendrons imparted integrin-mediated cell adhesion as evidenced by the formation of stress fibers. …
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The Synthesis and Characterisation of Novel Low Molecular Weight Gelators and their Applications in Electrospinning to Develop Biocompatible Materials and Tissue Scaffolds
… derivatives of galactosyl, L and D/L (racemic) aspartic acid. Two families of glycolipids (O-linked and N-linked) were evaluated as LMWGs. It was found that structural features such as the chirality of the aspartic acid core or the nature of the glycosidic bond strongly affect the gelation …
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Structural studies of Butirosin D and FrbG
… two is histamine (H14 and H163) residues and one aspartic acid (D16) residue coordinate a metal ion, believed to act in concert with another aspartic acid residue (D19) as the Lewis acid for the reaction to occur. Residues surrounding this relatively deep motif are likely to direct both ligand …
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Characterization of leucyl-TRNA synthetase from homo sapiens and escherichia coli in aminoacylation, amino acid editing and interdomain interactions
… discriminator and universally conserved aspartic acid that were mutationally characterized. Substitution of threonine to alanine uncoupled specificity similar to other LeuRSs. However, the introduction of bulky residues in the amino acid binding pocket failed to block deacylation of tRNA, …
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