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Showing 1 to 7 of 7 for “"ascarosides"”.
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I. Synthesis of Ascarosides for Biological Evaluation and II. Development of Visible Light-Promoted Selenofunctionalization and Grafting of Aryl Iodides
… consisting of a group of previously-isolated ascarosides. These compounds differ in chain length, saturation, terminal functionality of side chain, ω vs. ω-1 oxygenation and presence of an indole-3-carboxyl protecting group. The roles that these various functionalities play in dauer formation …
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I. Synthesis of Ascarosides for Chemical Biology Studies in Caenorhabditis elegans, II. A Photochemical Approach to Delavayine, and III. Remote Hydroxylation by Radical Translocation and Polar Crossover
… of the dideoxy sugar ascarylose. Referred to as ascarosides, such compounds have recently been shown to influence important biological processes in the model organism Caenorhabditis elegans. C. elegans secretes ascarosides into its environment, where the compounds then act as signaling molecules …
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The Neural Circuit for Behavioral Responses to Pheromone and Social Behavior in Caenorhabditis Elegans
… pheromones are a set of related compounds called ascarosides. Specific ascarosides are known to regulate development and male attraction to potential mates. To characterize hermaphrodite responses to ascarosides, I used a behavioral assay for acute avoidance called the drop test, which measures …
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The Molecular Signatures of Adaptive Plasticity in Parasitic Nematodes
… firstly, the identification of molecules (ascarosides) externally secreted by IJs and their effects on dispersal, and secondly changes in behaviour and stress tolerance of IJs over time during storage at different temperatures, and associated changes in the proteome. When the host cadaver …
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Pheromones in entomopathogenic nematodes: effects on dispersal and reproductive behaviours
… analysis which revealed the presence of numerous ascarosides, the family of molecules known to be involved in nematode communication, in active fractions. S. carpocapsae was previously reported to produce ascarosides at both juvenile and adult stages of the life-cycle; however this study is the …
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The Neural Circuitry Of Social Behavior In C. elegans
… Indeed, npr-1 social feeders are attracted to ascarosides, while N2 solitary feeders are repelled, a behavioral difference that is dependent on RMG function. Calcium imaging of ASK and its postsynaptic partner AIA demonstrated that RMG promotes signaling from ASK to AIA. Taken together, these …
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The Automatic Tracking Of <i>Caenorhabditis elegans</i> And Its Use In Determining Genetic Function
… dauer entry in response to exogenous, purified ascarosides. Mutations in <i>acd-5</i> cause decreased lifespan and healthspan and a reduction in dauer entry in response to crude dauer pheromone. This suggested that the two genes were unlikely to be working in the same pathway, but do function in …