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Showing 1 to 13 of 13 for “"arylamines"”.
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Copper-catalyzed carbon-heteroatom bond formations : asymmetric hydroamination and continuous-flow aromatic Finkelstein reaction
… protocol for the synthesis of enantioenriched N-arylamines (Chapter 1) and 1,2- diamines (Chapter 2). The second part of this dissertation describes the development of copper-catalyzed aromatic Finkelstein reaction under continuous-flow conditions (Chapter 3). Part I. Chapter 1.
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Advances in palladium-catalyzed carbon-nitrogen bond forming processes
… resulted in good to excellent yields of arylamines in short reaction times. Chapter 2. Using a catalyst comprised of the bulky, electron-rich monophosphine ligand di-tert-Butyl XPhos (2-di-tert-butylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl) and Pd2dba3 with sodium tert-butoxide as …
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Iron-mediated Synthesis of the Antiostatins
… a cyclohexadienylium iron salt and appropriate arylamines. This transition metal-mediated approach could be applied to all antiostatins in excellent yields. The antiostatins A1-4 and B2-5 represent the first carbazole alkaloids with an acetamide or substituted biuret chain. Introduction of the …
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Development and Mechanistic Investigation of the Palladium-Catalyzed Alpha-Arylation of Aldehydes and N-Arylation of Ammonia
… a solution of ammonia in dioxane formed primary arylamines from a variety of aryl electrophiles in high yields. Catalyst loadings as low as 0.1 mol % were sufficient for reactions of many aryl chlorides and bromides. In the presence of this catalyst, aryl sulfonates also coupled with ammonia for …
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Charakterisierung des allergenen Potentials von Arylaminen : in vitro Studie zur Reaktivität von T-Lymphozyten
… of different para-amino compounds and arylamines in vitro by measurement of T-cell proliferation of PBMC, T-cell lines and T-cell clones of subjects with a positive patch test result to para-Phenylenediamine. T-cell clones were generated from the blood of 14 cases and their …
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Gold(I) and Platinum(II)-Catalyzed Hydrofunctionalization of Allenes and Alkenes with Carbon and Nitrogen Nucleophiles
… with 1-alkenes. Various carbamates, arylamines, amide derivatives, sulfur-containing amide derivatives, and α-heteroatom compounds failed to react with 1-octene under gold(I)-catalyzed conditions.</p></p><p><p>A chiral bis(gold) phosphine complex catalyzed the stereoconvergent, …
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Characterization and reconstitution of enzymes and pathways in the biosynthetic production of nitroaromatic compounds
… The prototypical enzyme for N-oxygenation of arylamines is the protein AurF from Streptomyces thioletus. In this thesis, further characterization of this enzyme is performed for protein engineering. The activity of the enzyme was increased more than 600-fold from previous literature results by …
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Development and mechanistic investigation of the palladium-catalyzed α-arylation of aldehydes and N-arylation of ammonia
… a solution of ammonia in dioxane formed primary arylamines from a variety of aryl electrophiles in high yields. Catalyst loadings as low as 0.1 mol % were sufficient for reactions of many aryl chlorides and bromides. In the presence of this catalyst, aryl sulfonates also coupled with ammonia for …
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The plant-activation of m-phenylenediamine and its mutagenic, biochemical and molecular characterization
… suggests that plantactivation mechanisms for arylamines fundamentally differ from that of mammalian activation. S. typhimurium tester strain YG1024 was treated with plant-activated m-PDA metabolites. The genomic DNA was analyzed using the $\sp{32}$P-postlabeling method. DNA adducts were …
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Selective Chemical Reactions for Nucleic Acid Sequencing and DNA-Encoded Library Synthesis
… between on-DNA secondary N-substituted (hetero)arylamines and vinylarenes is explored as a method to generate DELs with known bioactive architectures. The developed reaction proceeds efficiently with a broad and well-explored substrate scope, working best with electron poor to neutral …
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Novel near-infrared absorbing dyes
… condensation reaction between croconic acid and arylamines. The results indicated that the optimum reaction conditions involved using a low proportion of an alcohol in a nonpolar aprotic solvent in the presence of a weak acid catalyst. Dyes were also obtained from the reaction of various …
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Palladium-catalyzed reactions of ammonia, carbon monoxide, and cyanide
The reductive eliminations of primary arylamines from a series of bisphosphine-ligated arylpalladium(II) parent amido complexes countered several established trends. In contrast to arylamido and alkylamido complexes of the aromatic bisphosphines DPPF and BINAP, parent amido complexes did not form …