Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"area per lipid"”.
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Adsorption of phloretin to lipid layers
… of action of phloretin and its analogs on the permeability of natural membranes for neutral and charged molecules, such as urea, glucose and chloride has been characterized 25 years ago. In contrast to signal molecules with primary effects on transport systems of natural membranes, phloretin …
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Effect of repurposed drugs on the cellular properties of childhood cancer: in vitro & in silico studies
… changes within the cell were monitored experimentally through the cell viability MTT assay. Biological changes were also monitored computationally using molecular dynamics (MD) simulations. Three models for cell membranes were proposed, one model for cancer membrane and two models for …
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Biological membrane in presence of alcohol and anti-asthma drugs: a molecular dynamics study
… of alcohol and anti-asthma drugs on phospholipid bilayer a series of atomistic molecular dynamics (MD) have been carried out. Although alcohol is widely used as a solvent in drug delivery systems, it is known that it can affect a lipid bilayer. The effect of two different alcohol molecules …
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Engineering the future of Hybrid Materials with Coarse-Grained Molecular Dynamics
… materials science by combining the distinct properties of polymers, nanoparticles, ceramics, metal oxides, and biomolecules to create adaptable, high-performance systems tailored to complex applications. These materials are critical in areas such as energy storage, environmental sustainability, …
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Uncovering Structure-Property Relations in Biomimetic Lipid Membranes with Molecular Additives
The lipid bilayer, the fundamental structure of cell membranes, exemplifies a highly adaptable molecular assembly with characteristics that have been fine-tuned through evolution to meet the diverse functional needs of cells. These bilayers must strike a delicate balance: they need to be …
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Lipid Composition and Configuration Drive Biophysical Properties of The Mammalian Plasma Membrane
<p>In the 1970s, it was established that phospholipid (PL) classes are asymmetrically distributed across the (PM) leaflets. Recapitulating strategies coupled with newly developed, high-resolution shotgun lipidomics, our lab confirmed PL class asymmetry and surprisingly measured the endoplasmic …
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Computational modeling of peptide-mediated charge transport and membrane-associated phenomena
… mechanisms of biophysical and biochemical experiments. It is a particularly effective technique for uncovering atomic-level interactions that contribute to experimental observables. First, I explore the structure-activity relationships governing transmembrane ion conductance mediated by …