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Showing 1 to 20 of 57 for “"aquaporin"”.
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Trafficking of aquaporin-2 in health and disease
Contains fulltext : mmubn000001_345930894.pdf (Publisher’s version ) (Open Access)
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Expression and Function of the Nicotiana tabacum Aquaporin NtAQP1
… und zeitlichem Expressionsmuster von dem Aquaporin NtAQP1 und seiner Funktion im Wasserhaushalt in planta. Immunologische in situ-Studien deuteten auf eine NtAQP1-Protein-Akkumulation in der Wurzelexodermis und -endodermis, im Cortex, in der Nähe der Leitbündel, im Xylemparenchym und in …
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Aquaporin-4 mediates blood brain barrier permeability during endotoxemia
Aquaporin-4 (AQP4) is a water channel expressed on astrocytes known to regulate the exchange of fluids and solutes between the parenchyma of the central nervous system (CNS) and perivascular spaces. We hypothesized that activation of AQP4 may mediate permeability of the CNS during systemic …
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Modulation of the aquaporin-2 localization in renal principal cells
… (protein kinase A, PKA), the water channel aquaporin-2 (AQP2) is redistributed from intracellular vesicles into the plasma membrane of renal collecting duct principal cells. Its insertion into the plasma membrane induces the water reabsorption from primary urine and fine-tunes body water …
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The mechanisms of aquaporin expression and translocation in cerebral pathologies
Aquaporins (AQPs) are membrane proteins that regulate the selective bidirectional water and solute transport across biological membranes and are essential for maintaining cellular integrity. In humans, the AQP family consists of 13 established members (AQP0-12). AQPs 1, 3, 4, 5, 8, and 9 are …
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BIOMIMETIC MEMBRANES EMBEDDED WITH AQUAPORIN Z FOR WATER REUSE AND DESALINATION
… study on the design and fabrication of AquaporinZ (AqpZ)-embedded biomimetic membrane. Firstly, the mechanical property of the artificial AqpZ-embedded lipid bilayer membrane was explored. Secondly, the performance of biomimetic membrane has been has been demonstrated in forward osmosis. …
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Aquaporin 3 Water Channel Protein Gene Expression in Squalis Acanthias Dogfish Shark
Aquaporins are a family of membrane proteins that provide channels for the rapid movement of water molecules and some small solutes across the cellular membrane. Since the discovery of the first water channel protein, hundreds of homologous proteins have been found in all forms of life and much has …
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Studies of transcriptomic mechanism for sugarcane biomass production and aquaporin in pineapple
… level mechanism of water regulation related aquaporin gene family and revealed the rhythm of aquaporin transcripts, which is possibly relevant to water use efficiency (WUE). These studies have helped us gain more insights of trancriptomic mechanisms of hormones, ploidy levels, and aquaporins …
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Contribution of Causal Aquaporin-1 Mutations to the Pathobiology of Pulmonary Arterial Hypertension
… rare causative heterozygous variants in the Aquaporin-1 (AQP1) gene were identified among a small subgroup of PAH patients. AQP1 is a water channel protein critical for maintaining endothelial cell integrity and fluid homeostasis. The primary aim of this thesis is to provide insight into the …
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Pharmacologically impeding glioblastoma tumour motility through simultaneous inhibition of aquaporin-1 and ion channels
… pathways that control cellular motility include aquaporins and ion channels. These protein classes could therefore be prime candidates as pharmacological targets to restrain cell motility in glioblastoma. Identifying optimal combinations of inhibitory agents to use against selected channel …
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An Analysis of the Arabidopsis Aquaporin TIP1;1 and Analysis of Stress Response Signaling in Arabidopsis
The stress response pathways in Arabidopsis were studied, using publically available Affymetrix ATH1 microarray data. The salt stress signaling pathways were dissected, by comparing the salt stress response to other abiotic/biotic stress responses or the response to plant hormones. The analysis, …
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Pharmacological Modulation of Cancer Migration and Invasion Through Targeting AQP1 Ion and Water Channel Activity
… are the leading causes of cancer-related deaths. Aquaporin-1 is a dual water and ion channel that is upregulated in many aggressive cancers including colon, breast, and brain cancer; aquaporin-1 enhances cell migration, invasion and metastasis in these cancer types. Other aquaporins with water …
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Aquaporin 4 and Kir4.1 Distribution in Retinal Glial Cells of Normal Macaque Eyes and Eyes with Experimental Glaucoma
… the study was to determine the distribution of aquaporin 4 (AQP4) and a potassium inward rectifying channel (Kir4.1) in the Müller glia and astrocytes of the normal macaque monkey retina and to see how the distribution changed in eyes with experimental glaucoma. Methods: Five Rhesus macaque …
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Investigating hydrogen peroxide dynamics and the role of plasma membrane aquaporin PIP1:4 in plant sensitivity to ozone.
… control. Rosette growth in Col and aquaporin lines was impaired by growth at chronic elevated ozone of 150ppb 8 h/day, though significant increases in leaf H2O2 content were only found in wildtype Col and overexpressing line OE4.2. In response to acute ozone exposure, 350 ppb for 6 h …
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Osmoregulation in Trypanosoma Cruzi: The Role of the Acidocalcisome
… all three life cycle stages of the parasite. An aquaporin homologue localized to the acidocalcisomes and contractile vacuole. In epimastigotes expressing a GFP-aquaporin fusion protein, acidocalcisomes trafficked toward the contractile vacuole during hyposmotic stress in a cAMP- and …
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Development of biomimetic, hybrid protein-synthetic membranes: determining protein insertion efficiency, membrane material suitability and relevance of aquaporin Z
… such as the bacterial water channel protein aquaporin Z (AqpZ), embedded in a lipid bilayer or a polymer that mimics a cell’s natural lipid bilayer. Permeability and stability pose critical barriers to implementation of biomimetic AqpZ-based membranes. To achieve maximum permeability, it is …
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CHARACTERIZATION AND FUNCTIONALITY OF RECOMBINANT AQUAPORINS FROM MOZAMBIQUE TILAPIA
… cost biomimetic membrane incorporated with aquaporin, having high water selectivity and permeability, are of interest. Hereby, we propose that Mozambique tilapia (Oreochromis mossambicus) aquaporins are potential candidates for the biomimetic membrane due to the ability of this tilapia to …
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Development of Thin-Film Composite Membranes Incorporated With Graphene Oxide and Derivatives for Forward Osmosis Processes
… defects and improve membrane performance. Next, Aquaporin was added with GO in the PA layer to improve the membrane selectivity as Aquaporin healed the non-selective PA defects created by the GO flakes. Finally, the effect of GO quantum dots (GQDs) on the interfacial polymerization (IP) reaction …
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Molecular Mechanisms of Gating, Selectivity, and Transport in Membrane Channels and Carriers
… across biological membranes. The water channel aquaporin (AQP) and the nucleotide transporter ADP/ATP carrier (AAC) are the focus of the research presented in this thesis. By facilitating water conduction across cellular membranes, AQPs play a significant role in water homeostasis in living …
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