Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"aortic dissection"”.
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Investigating Medical Examiners' Practices: Genetic Evaluation For Fatal Acute Aortic Dissection
<p>Acute thoracic aortic dissection (TAD) is a life-threatening event with a hereditary component. Currently, pathogenic variants in 11 genes associated with aortic aneurysm and dissection predispose to a heritable form of disease thereby conferring an increased risk for TAD. Genetic testing plays …
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Late Complications in the Descending Aorta Following Valve-Sparing Root Replacement (VSRR) in Marfan Syndrome (MFS) Patients: A Computational Analysis
… Syndrome (MFS) experience an elevated risk of aortic dissection in the descending aorta (DA) following root surgery. Geometric factors related to either native anatomy or the root surgery may alter hemodynamic factors in the DA, potentially predisposing it to dissection. This study uses …
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Fibrous Microstructure and Biomechanics of Healthy and Diseased Aortic Tissues
… collagen and elastin fibre parameters of human aortic dissection flaps were extracted from histology slides. Their material properties and relationships with fibrous parameters were also studied. Secondly, a computational framework based on the unsupervised deep learning UNet model was proposed …
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Novel imaging and blood biomarkers in acute aortic syndrome
BACKGROUND: Acute aortic syndrome is an unpredictable and catastrophic condition. It is characterised by medial degeneration which is beyond the resolution of conventional anatomical imaging. Here, we investigate 18F-sodium fluoride positron emission tomography and computed tomography (PET/CT) and …
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Mechanical Effects of Surgical Adhesives on Ascending Thoracic Aortic Aneurysm Replacement
<p>Ascending thoracic aortic aneurysm (aTAA) is a potentially lethal disease which grows gradually over time and may lead to aortic dissection and rupture. Currently, aTAA surgical repair using Dacron graft is a well-established treatment. In addition, surgical adhesives are frequently used in the …
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Novel strategies to increase Sirtuin-1 activity in aortic aneurysm
… and anti-oxidant effects on the aortic wall are involved in preventing vascular diseases, such as aortic aneurysm (AA) and dissection. We demonstrated that SirT1 in vascular smooth muscle (VSM), the major component of large arteries, is indispensable in maintaining vascular wall …
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Imaging microcalcium in thoracic aortic disease
… complications occur, such as stroke or aortic dissection. Current management strategies focus on preventative interventions which can include high-risk surgery. However, identifying those who are most appropriate for such interventions is challenging. Deposition of calcium crystals …
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Relación entre variaciones anatómicas del cayado de la aorta, aneurismas y disección. Estudio de casos y controles en Hospital de Méderi, Bogotá, Colombia 2010-2021
Introducción: La disección y aneurisma de la aorta son enfermedades que presentan una baja incidencia y prevalencia. A pesar de ello generan elevadas tasas de morbimortalidad, procedimientos complejos que habitualmente requieren largos periodos de hospitalización en Unidades de Cuidado Intensivo y …
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Effect of microstructure on mechanical behaviour of arterial tissue
… deaths caused by cardiovascular diseases (CVDs), aortic aneurysms (AAs) and aortic dissections (ADs) is more than from any other cause. Most CVDs are a result of atherosclerosis, in which a fibrous cap covered lipid-rich plaque is formed in the arteries. The fibrous cap can rupture, blocking the …
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Mechanism of Rare Variant In Acta2, P.Arg149Cys, Driving Diverse Vascular Disease
… muscle (SM) α-actin) predispose to thoracic aortic aneurysms and dissections (TAAD) and early-onset coronary artery disease (CAD). The most common <em>ACTA2</em> mutation is a genetic alteration of arginine 149 to a cysteine, <em>ACTA2</em> p.Arg149Cys, which accounts for disease in 24% of …