Global ETD Search
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Showing 1 to 4 of 4 for “"anxiolytic effect"”.
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INTRACRANIAL INFUSIONS OF NEUROTENSIN AGONISTS PRODUCE AN ANXIOLYTIC PROFILE IN A RAT ULTRASONIC VOCALIZATION MODEL
… number of 22-kHz USV calls is indicative of an anxiolytic effect. The current study used a USV model to evaluate the effects of PD149163 (0.1, 1.0, and 10.0 ng) and endogenous NT (0.1, 1.0, and 10.0 µg) when administered into the lateral ventricle of male Wistar rats. Both 10ng of PD149163 and …
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Caratterizzazione del clofibrato agonista sintetico dei recettori dei proliferatori dei perossisomi (PPARα)in modelli animali di depressione ed ansia
… have been published on PPARα mediated behavioral effects, which suggests that PEA exerts anxiolytic and antidepressant-like effect in mice (Crupi et al., 2013, Yu et al., 2011). However no studies have been evaluated antidepressant-like effect of synthetic PPARα agonists. Thus, the aim of our …
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Role of the Endocannabinoid System in Behavioral Reactions in a Depressive-Like Condition // Роля на ендоканабиноидната система в поведенчески реакции при депресивно-подобно състояние
Ендоканабиноидната система (ЕКС) е медиаторна система с липидни медиатори. Основните ѝ компоненти са канабиноидните рецептори (СВ1R и СВ2R) и ендоканабиноидите – N арахидоноилетаноламин (анадамид) и 2-арахидоноилглицерол. Участва в широк спектър физиологични процеси: ноцицепция, двигателен контрол, …
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Prostaglandin EP3 receptor signalling as a contributor to sex differences in stress-related disorders mediated by the locus coeruleus
… potentiated analgesia in females, while no effects were observed in males. These evidences highlight a sex-specific role for LC-EP3 signalling in the regulation of stress responses. To further investigate the functional relevance of LC activity in females, chemogenetic activation of LC …