Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 18 of 18 for “"antral follicles"”.
-
Mechanism of methoxychlor toxicity in mouse ovarian antral follicles
… MXC reduces fertility by increasing atresia of antral follicles and by decreasing numbers of healthy antral follicles in adult female mice. Further, MXC inhibits growth and induces atresia of mouse antral follicles in vitro. Little is known, however, about the mechanisms by which MXC causes slow …
-
Effects of methoxychlor and its metabolites on mouse antral follicles
… well as in vivo. Results indicate that ovarian antral follicles of ESR1 OE are more sensitive to growth inhibition and atresia induced by MXC and its metabolites compared to controls. Moreover, MXC and its metabolites cause differential gene expression of nuclear receptors and pro-apoptotic …
-
Mechanism of Bisphenol A toxicity in adult mouse ovarian antral follicles
… as ovarian follicle growth and steroidogenesis. Follicles are the functional units of the ovary, responsible for ovulating an oocyte and producing sex steroid hormones during steroidogenesis. Follicles grow and develop from primordial, primary, pre-antral, and finally, to antral follicles over …
-
Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles
… examined the direct effects of equol on intact antral follicles, which are responsible for sex steroid synthesis and further development into ovulatory follicles. The present study tested the hypothesis that equol inhibits antral follicle growth, increases follicle atresia, and inhibits …
-
Toxicity of TCDD in the mouse antral follicle
… growth, and atresia of intact mouse antral follicles in vitro. Interestingly, TCDD has been shown to act mainly through binding to the aryl hydrocarbon receptor (AHR) in other tissues, and the AHR has been identified as an important factor in ovarian function. Thus, these studies were …
-
Toxicity and detoxification of imidacloprid in mouse ovarian follicles
… 3, I compared the effects of IMI and DNI on antral follicle physiology in vitro. Antral follicles were cultured with a vehicle control (DMSO or ultrapure water), IMI (0.2 - 200 µg/mL), or DNI (0.2 - 200 µg/mL) for 48, 72, and 96 hours. Specifically, I evaluated follicle growth, morphology, …
-
The effects of an environmentally relevant phthalate mixture on female reproduction
… are born with a finite pool of primordial follicles, and the size of primordial follicle pool determines the reproductive lifespan. To form the finite pool of primordial follicles, germ cells must undergo mitosis, formation of germ cell nests, meiosis, and germ cell nest breakdown. Any …
-
Mechanisms by which di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate disrupt ovarian folliculogenesis and steroidogenesis
… are folliculogenesis and steroidogenesis. Follicles are the functional units of the ovary containing the oocyte required for ovulation and fertilization and somatic cells responsible for synthesizing sex steroid hormones. Folliculogenesis is the process by which follicles undergo several …
-
Studies of the mammalian ovarian endothelin system
… cells of large (10 mm) and medium (3 mm) antral follicles. This study, in conjunction with previous studies suggests a novel autocrine role of ET-1 as a possible local ovarian factor of follicular development. ET-1 may play a role during prostaglandin (PG) F2 alpha-induced luteal …
-
Endocrine markers of ovarian function: Clinical and biological aspects with focus on Anti Müllerian hormone
… potential are often requested. Currently the antral follicle count and the Anti Müllerian Hormone (AMH) level are considered to be the most predictive markers. The two markers roughly describe the same issue as they are both related to certain developmental stages of the folliculogenisis. …
-
The aryl hydrocarbon receptor signaling pathway and adverse reproductive outcomes
… senescence by directly targeting ovarian follicles. Thus, in my dissertation work, I tested the hypothesis that various doses of bisphenol A (BPA) inhibit growth and reduce estradiol biosynthesis in isolated mouse antral follicles. I also tested the hypothesis that the toxic effects of BPA …
-
Transcriptional profiles of cumulus-oocyte complexes related to developmental competence in bovine oocytes
… from an abattoir, COC were collected from follicles ranging from 3 to 8 mm in diameter. Cumulus-oocyte complexes were incubated in the supravital stain brilliant cresyl blue (BCB) as a means of separating oocytes based on the growth phase. Fully developed oocytes remained stained and were …
-
Impacts of perfluorooctanoic acid on porcine oocyte health and competence
… is the female gamete and develops within ovarian follicles and has intimate connection with the ovary, the ovarian blood supply, and the follicular fluid of antral follicles. Per- and polyfluoroalkylated substances are environmental toxicants that have been detected in the follicular fluid of …
-
TRANSCRIPTOME LANDSCAPE OF EARLY FOLLICULOGENESIS IN MAMMALS: UNLOCKING THE INTERPLAY MECHANISMS TO ENHANCE ART EFFICIENCY IN FERTILITY PRESERVATION
… of the female gamete reserve, specifically the antral follicles. In contrast, the preantral follicle population, which represents 99% of the reserve, remains unexploited. To date, no established culture system has been successfully adopted to replicate folliculogenesis in vitro, as existing …
-
The distribution and speciation of trace elements in bovine ovaries using synchrotron techniques
… all imaged tissues. By classifying the ovarian follicles according to their health status, as well as their size (follicular diameter), and extracting average elemental concentrations for these follicles from the XRF images, it was possible to quantitatively analyse the cohort of 97 imaged …
-
Fortpflanzungsphysiologie und assistierte Reproduktion beim Haushund (Canis familiaris) - eine Literaturstudie
… of IVM. Dog oocytes cultured within advanced preantral and early antral follicles in vitro are competent to resume meiosis and mature to the metaphase stage. The developmental potential of these oocytes was comparable to isolated cumulus oocyte complexes. The optimal culture conditions required …
-
Prenatal exposure to phthalates accelerates reproductive aging in multiple generations of female mice
… cyclicity, decreased the percentage of ovarian follicles, and dysregulated hormones in the HPG axis in the F3 generation. Next, I tested the hypothesis that prenatal exposure to an environmentally relevant phthalate mixture accelerates biomarkers of reproductive aging in a multiple and …
-
The effects of adult exposure to genistein on female reproductive outcomes
… immature primordial follicle to the most mature antral follicle. The antral follicle is one of the most important follicle types because it is the primary producer of sex steroid hormones in the ovary, and it is the only follicle type capable of growing to the point of ovulation. Therefore, any …