Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"antiviral target"”.
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CHARACTERIZATION OF INFLUENZA NUCLEOPROTEIN BODY DOMAIN AS ANTIVIRAL TARGET
… A isolates, making NP interactions compelling antiviral targets. Here I characterize mutations within 5 amino acids of NP that comprise an accessible region of the NP body domain, as determined by NP crystal structure. This region was selected for mutagenesis to target interaction between NP …
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The function of the hepatitis C virus p7 protein
… is thus important for developing new therapeutic targets. The HCV p7 protein is critical for virus production and an attractive antiviral target. p7 is an ion channel when reconstituted in artificial lipid bilayers, but channel function has not been demonstrated in vivo and it is unknown whether …
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Differential modulation of HIV-1 capsid uncoating kinetics revealed by a novel single-particle uncoating assay
… capsid has been recognised as an attractive antiviral target due to its central role during infection. It acts as a shield to protect the viral genome, facilitates reverse transcription, engages with the nuclear pore complex, and directs integration site targeting. To achieve all of these …