Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"antithrombotic drug"”.
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Is the door closed? : In vitro studies on the pharmacokinetic effects of OATP1B1 gene-drug and drug-drug interactions.
… diverse endogenous substances as well as drugs and other xenobiotics. OATP1B1 is located in the sinusoidal (blood-facing) membrane of hepatocytes and is an integral part of hepatic distribution and elimination of many of its substrates. OATP1B1 function can be impaired (the door get …
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Investigating small-molecule inhibitors of platelet aggregation
… thrombotic events. However, current antiplatelet drugs have several drawbacks such as the increased risk of bleeding, difficulty in fine-tuning the antiplatelet effects of irreversible antagonists, and variability in patient response. Furthermore, the nucleoside-based, reversible drug ticagrelor …