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Showing 1 to 1 of 1 for “"antisense oligonucleotide therapy"”.
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Exploring SARM1 as a target to delay programmed axon degeneration
… be beneficial. Secondly, targeting SARM1 through antisense oligonucleotides shows that SARM1 protein levels can be decreased in vitro to a similar extent as Sarm1 hemizygosity using exogenously-applied nucleotides. This decrease in protein levels confers a delay in programmed axon degeneration in …