Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 102 for “"antipsychotic"”.
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Discriminative Stimulus Effects of Putative Antipsychotic Drugs
… the discriminative stimulus properties of antipsychotic drugs, by establishing the typical antipsychotic drug chlorpromazine, and the atypical antipsychotic drug clozapine as discriminative stimulus in two different groups of rats. The rats trained to discriminate chlorpromazine from …
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The management of antipsychotic-induced weight gain
… to the burden of CVD among SMI cohorts. Whilst antipsychotic medications are essential treatments in psychiatry, the prescription of any antipsychotic substantially increases the risk of developing obesity. Thus, effective management of antipsychotic-induced weight gain (AIWG) is paramount in …
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Enhanced striatal glutamatergic function upon chronic antipsychotic action
… impaired executive function. Currently available antipsychotics mitigate some symptoms of schizophrenia, particularly the positive symptoms, but there is no preventive treatment nor cure after schizophrenia develops. Efforts to generate more effective antipsychotics are made particularly …
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Understanding the impacts of antipsychotic pharmaceuticals on behaviour in fish
… neuroactive pharmaceuticals, and particularly antipsychotic drugs (APDs), represent an emerging environmental concern due to their pseudo-presence, bioaccumulative potential and potency in modulating central nervous system (CNS) targets. APDs act on evolutionarily conserved monoaminergic, …
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Optimizing Antipsychotic Use across Nursing Homes: Implications for Dementia Care
… contextual factors associated with initiation of antipsychotics among short-stay nursing home residents with dementia; (2) evaluate the relationship of nursing home level initiation of antipsychotics with all-cause hospitalization and mortality; and (3) examine individual and contextual factors …
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The lived experiences of people with schizophrenia prescribed atypical antipsychotic medication
… as opposed to the older forms of typical antipsychotic medication. The older (typical) neuroleptic forms of medication have been shown to produce unpleasant side-effects that cause severe problems with everyday functioning and thus affect patients’ quality of life. Existing research has …
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The Role of Vitamin D and Antipsychotic Drug-induced Weight Gain
… Pharmacotherapy in the form of second generation antipsychotic drugs (SGAs), including quetiapine, is the primary treatment for schizophrenia; however, the growth in utilization of these medications has led to a simultaneous rise in the occurrence of weight gain and metabolic syndrome in this …
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Psychosocial Processes Influencing Weight Management Among Persons Newly Prescribed Atypical Antipsychotic Medications
… among persons newly prescribed atypical antipsychotic medications. RESEARCH QUESTIONS: 1. What influences weight management in persons with first-episode psychosis who are newly prescribed atypical antipsychotic medications? 2. How is weight management facilitated in persons with …
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Antipsychotic drugs for the treatment of acute schizophrenia after the first episode
Background: Antipsychotic drugs (APDs) represent the treatment of choice for psychotic disorders, but uncertainty surrounds the optimal selection of agents. Methodology: This was a mixed method study which included a systematic review and psychiatrists’ opinion survey. The systematic review focused …
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The Discriminative Stimulus Properties of the Atypical Antipsychotic Clozapine in C57BL/6 Mice
… receptor antagonism may contribute to atypical antipsychotic drug effects. Clozapine (2.5 mg/kg) drug discrimination in C57BL/6 mice may selectively screen atypical antipsychotic drugs. Previous data show that the atypical antipsychotics olanzapine, risperidone, ziprasidone but not the typical …
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The impact of antipsychotic drugs on the expression of genes associated with obesity
… debilitating disorder, primarily treated with antipsychotic medication. Weight gain is a serious side-effect associated with most second generation antipsychotic drugs such as clozapine. The mechanism behind clozapine-induced weight gain remains poorly understood, but changes in eating …
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A DNP project : implementation of a monitoring agreement for patients receiving antipsychotic treatment
… evaluated the implementation of a standardized antipsychotic monitoring and informed consent form within an outpatient psychiatric practice. The aim was to improve documentation of informed consent and adherence to guideline-based metabolic monitoring among psychiatric mental health nurse …
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Learning to Dance in the Rain: Stories of Young People taking Antipsychotic Medication
… approximately 50% of young people do not take antipsychotic medication as prescribed. This research was designed to explore factors which may promote and deter teenage adherence with antipsychotic medication. Initially intended as a quantitative study, the research pragmatically shifted to a …
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A Nurse-Driven Protocol To Increase Metabolic Screening And Interventions For Inpatients On Antipsychotic Medications
<p>Patients on antipsychotic medications are at higher risk of developing metabolic syndrome; nevertheless, metabolic screening for patients on antipsychotics is suboptimal. This project implemented a nurse-driven protocol on inpatient psychiatric units to increase metabolic screening compliance …
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The gut microbiota as a contributing factor to antipsychotic-induced weight gain and metabolic dysfunction
… recent decades with the discovery of several antipsychotic compounds; however these drugs are not without adverse effects that must be addressed to maximize their therapeutic value. Newer, atypical, antipsychotics are associated with a compilation of serious metabolic side effects including …
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A retrospective observational study of the effectiveness of long acting antipsychotic injectable on hospital admissions
… relapse rates of utilising long-acting antipsychotic injectable (LAIs) in a South African population suffering from chronic psychotic spectrum mental illness is poorly researched. Aim: To compare the duration and number of hospitalisation episodes 12 and 24 months before and after the …
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The prevalence and predictors of antipsychotic medication non-adherence among clients with psychotic disorders in Mzimba, Malawi
… is one of the severe forms of MNS disorders. Antipsychotic medications play a significant role in the treatment and management of schizophrenia. However, non-adherence to antipsychotic medication is a recognized problem. At the present time, a majority of the research investigating …
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A problem-solving based peer support program for enhancing adherence to oral antipsychotic medication in consumers with schizophrenia
… with schizophrenia are reluctant to take their antipsychotic medications, and this might have adverse implications for their recovery. Numerous approaches have been implemented to enhance medication taking for this population, but results have varied. The overall aim of the study was to assess …
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A descriptive analysis of antipsychotic prescribing patterns for patients admitted to hospital with a primary diagnosis of schizophrenia
Treatment with antipsychotic medication is recognized as the standard treatment for patients with schizophrenia. While evidence-based recommendations have been made on antipsychotic prescribing patterns for patients with schizophrenia, there is still a disconnect between these recommendations and …
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