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Showing 1 to 1 of 1 for “"antimutator; DNA polymerase; DNA replication; Dun1; error extinction; mutator phenotye"”.

  1. Isolation of antimutator yeast strains: an exploration of DNA replication fidelity

    DNA polymerases (Pols) delta and epsilon perform the bulk of eukaryotic nuclear DNA replication. Both Pols are high-fidelity enzymes with intrinsic proofreading exonucleases that remove errors during DNA synthesis. Errors that elude proofreading are extended into duplex DNA and excised by the …

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