Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 85 for “"antimicrobial resistance (AMR)"”.
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Antimicrobial resistance among pregnant women with urinary tract infections attending antenatal clinic at Levy Mwanawasa university teaching hospital Lusaka, Zambia
… in low income countries. The global emergence of antimicrobial resistance undermines the management of infectious diseases. Internationally, there is a growing concern over antimicrobial resistance (AMR) which is currently estimated to account for more than 700, 000 deaths per year worldwide. …
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Antimicrobial resistance among pregnant women with urinary tract infections attending antenatal clinic at Levy Mwanawasa university teaching hospital Lusaka, Zambia
… in low income countries. The global emergence of antimicrobial resistance undermines the management of infectious diseases. Internationally, there is a growing concern over antimicrobial resistance (AMR) which is currently estimated to account for more than 700, 000 deaths per year worldwide. …
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Factors contributing to AMR occurrence in infectious agents of broiler chickens in selected districts in Zambia.
Antimicrobial resistance (AMR) has remained one of the growing public health problems globally. The misuse and abuse of antimicrobials in agriculture, veterinary, and human medicine have been described as major contributing factors for the emergence of AMR. Globally, it is estimated that …
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Biogenic silver nanoparticles synthesized using eucomis autumnalis bulb aqueous extract, their characterization and in vitro antibacterial activity
Antimicrobial resistance (AMR) is a growing global problem that poses a significant threat to public health. AMR arises when microorganisms become resistant to drugs that were initially designed to kill them. The application of antibiotics has proven effective in eliminating or inhibiting the …
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GENOMIC SURVEILLANCE AND RISK-BASED ASSESSMENT OF ANTIBIOTIC RESISTANCE TRANSMISSION ACROSS TROPICAL AQUATIC ENVIRONMENTS
Antimicrobial resistance (AMR) transmitted through aquatic environments poses a growing public health threat, yet the genomic mechanisms governing resistance gene flow across interconnected water systems remain poorly understood. This thesis investigates β-lactam resistance transmission across …
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Pleuromutilin and its Application Towards Bidentate Antibiotics: Triazoles, Linker Chemistry, and Serendipitous Discoveries
The world is facing a global antimicrobial-resistance (AMR) crisis. Classes of antibiotics continually face ineffectiveness as resistance mechanisms in microbes develop and propagate. The semi-synthetic derivatization of natural product antibiotics has provided many of our treatments, but new …
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The discovery and functional study of a bioactive peptide QUB-1418 from the defensive skin secretion of the Wuyi torrent frog (Amolops wuyiensis)
… case of the increasingly serious situation of antimicrobial resistance (AMR), scientists have been studying antibacterial peptides (AMPs), which have great potential to be a substitute for antibiotics. <br/><br/>In this study, the cDNA sequence encoding a bioactive peptide named QUB-1418, and …
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Determining and Exploiting Common Interactions in the Peptidyl Transferase Center for Enhanced Derivative and Bidentate Design
… due to super-resistant bacterial infections. Antimicrobial resistance (AMR) is already responsible for nearly 5 million deaths a year. Ribosomes serve as an ideal drug target being frequently targeted by antibiotics and having a highly conserved structure with few options for resistance. …
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Specificity of Interaction of Antimicrobial Peptide with Cell Membrane
<p>Antimicrobial resistance (AMR) is an increasing global health threat due to its rising incidence worldwide. Resistant microbial infections have become difficult to treat and pose serious risks to patients. In 2019, AMR was responsible for approximately 1.27 million deaths globally, with numbers …
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Evolutionary Trade-offs Between Antimicrobial Resistance and Virulence in Pseudomonas aeruginosa
Antimicrobial resistance (AMR) threatens antibiotic efficacy, yet its evolutionary consequences for pathogen virulence and growth remain poorly resolved. This thesis addresses this gap using Pseudomonas aeruginosa, a multidrug-resistant pathogen capable of both acute toxin-mediated and chronic …
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Shotgun metagenomic analysis of antimicrobial resistance in wastewater
Antimicrobial resistance (AMR) threatens our modern standard of living with the potential return to a pre-antibiotic condition where deadly infections are no longer treatable. Wastewater treatment plants (WWTPs) are vital components in water sanitation infrastructure and are now also being …
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Using wildlife to biomonitor for antimicrobial resistance in the Scottish environment
Antimicrobial resistance (AMR) is a threat to global health. Surveillance of AMR<br/>bacteria in wildlife host is key to understanding and tracking their spread<br/>throughout our environment. We established baseline data on the prevalence of<br/>AMR E. coli in Scottish wild deer, utilising faecal …
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Identification and activity assessment of a bioactive peptide QUB-2995 from the skin secretion of the broad-folded Frog (Hylarana Latouchii)
… cell-mediated. Among these three sections, the antimicrobial peptides (AMPs) from humoral innate immunity, are a popular research area and have been paid much attention. They have no high specificity and can attack bacteria and kill them within minutes. At the same time, some can also damage the …
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A Framework for Standardized Monitoring of Antibiotic Resistance in Aquatic Environments and Application to Wastewater, Recycled Water, Surface Water, and Private Wells
Antimicrobial resistance (AMR) is a One-Health (human, animal, environment) challenge that requires collaborative, interdisciplinary action. Comparable surveillance data are needed to effectively inform policy interventions aimed at preventing the spread of AMR. Environmental monitoring lags behind …
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Food safety knowledge, attitude and practices of food handlers at the university teaching hospital in Lusaka.
… The study considered the isolation and antimicrobial resistance (AMR) of Staphylococcus aureus, contaminating correctional facility kitchens, in Lusaka Province, Zambia.A total of seventy-five (n=75) swab samples were collected from both facilities from table tops, food preparation …
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Food safety knowledge, attitude and practices of food handlers at the university teaching hospital in Lusaka.
… The study considered the isolation and antimicrobial resistance (AMR) of Staphylococcus aureus, contaminating correctional facility kitchens, in Lusaka Province, Zambia.A total of seventy-five (n=75) swab samples were collected from both facilities from table tops, food preparation …
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ZOONOSI, RESISTENZE ANTIMICROBICHE E INNOVAZIONE NELL¿ALLEVAMENTO DEL BOVINO DA LATTE: APPROCCI INTEGRATI SECONDO IL PARADIGMA ONE HEALTH
… medicine has promoted the global spread of antimicrobial resistance (AMR), with serious implications for public health and the sustainability of livestock farming. In this context, zoonotic pathogens such as S.aureus and S.agalactiae represent a complex threat, capable of crossing species …
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Factors that affect horizontal gene transfer in enteric bacteria
Antimicrobial resistance (AMR) has arisen as one of the most important public health concerns in the last 60 years. AMR results from pathogenic strains of bacteria adapting to antimicrobial-containing environments through mutations or through horizontal gene transfer (HGT) of genetic material …
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Advancing single cell microbiology and bacteriophage-bacteria interactions using microfluidics and image-based deep learning
The rapid rise of antimicrobial resistance (AMR) poses a critical global health threat, demanding innovative approaches for diagnosing infections and developing effective therapies. Conventional culture-based assays are often slow, labour-intensive, and limited in their ability to capture the …
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Identification and Inhibition of Fosfomycin Resistance Enzymes for Structure-Based Drug Design
Antimicrobial resistance (AMR) is a pressing issue facing modern medicine today. Bacteria are developing resistance to antibiotics faster than new antibiotics can be brought to market. Antimicrobial resistant infections are responsible for increased morbidity and mortality rates, as well as an …
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