Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 41 for “"antimicrobial agent"”.
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The Effectiveness of Camphorated Paramonochlorophenol, Metacresyl Acetate, and Prednisolone in Combination as an Antimicrobial Agent
… pain. It is imperative that a medicament retain antimicrobial activity while reducing inflammatory potential.</p> <p>This investigation was undertaken toward determining on an in vitro quantitative bactericidal versus bacteriostatic basis by use of the broth dilution test tube method whether …
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The Effects of Carbadox, a Synthetic Antimicrobial Agent, on Bile Acid Metabolism in The Domestic Pig
In order to study the bile acids of the young pig as they go through enterohepatic circulation without altering bile flow from the gall bladder, a surgical technique was developed to place indwelling catheters into the hepatic portal vein (HP) which allowed multiple sampling of the blood and did …
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The Effects of Carbadox, a Synthetic Antimicrobial Agent, on Growth, Nitrogen Balance, Protein Synthesis, Protein Degradation and Apparent Amino Acid Absorption in The Growing Pig
Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs
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QUB-1957: a bioactive peptide from the frog skin secretion of Hylarana latouchii
… for amphibians’ daily protection, especially the antimicrobial peptides. In this study, a cDNA library from lyophilised skin secretion of Hylarana latouchii was constructed, and molecular cloning of biosynthetic precursor-encoding cDNAs of QUB-1957 was performed. Subsequently, QUB-1957 was …
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Size Dependent Antimicrobial Properties of Sugar Encapsulated Gold Nanoparticles
<p>The antimicrobial properties of dextrose encapsulated gold nanoparticles (dGNPs) with average diameters of 25 nm, 60 nm, and 120 nm (± 5 nm) synthesized by green chemistry principles were investigated against both Gram-negative and Gram-positive bacteria. Studies were performed involving the …
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A dressing solution for burn wounds: antibacterial and low-adherent wound dressings
… is urgently needed. Silver ion is a widely used antimicrobial agent, but its cytotoxicity remains a problem. In this study, low-adherent PAM (polyacrylamide) hydrogel incorporated with less toxic AgNP (silver nanoparticle), was immobilized onto PET (poly(ethylene terephthalate)) substrates by an …
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Synthesis and inclusion studies of stable allicin mimics as novel antimicrobial agents
… constituent of garlic, is a potent but unstable antimicrobial agent. Consideration of the underlying features responsible for allicin’s activity, as well as its instability, prompted an investigation into substituted S-aryl alkylthiosulfinates as a class of potential allicin mimics with enhanced …
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Inhibition of <em>Escherichia coli</em> ATP Synthase by Polyphenols and Their Derivatives.
… modifications, and (III) if they can act as antimicrobial agent through their actions on ATP synthesis. X-ray crystal structures of polyphenol binding sites suggested that polyphenols bind at a distinct polyphenol binding pocket, at the interface of α,β,γ-subunits. We found that both natural …
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The synthesis and characterisation of novel ultra-flexible lipidic vesicles using propanol
… drug delivery system that could deliver the antimicrobial agent deeper into the outmost layer of the skin, the stratum corneum. The main objective of this study was to prepare a nanosized lipidic particulate drug delivery system that has an innate antimicrobial activity as well as the ability …
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A bioactivity peptide QUB2852 from the frog skin secretion of pelophylax nigromaculata
Due to the resistance of antibiotics, antimicrobial peptides (AMPs) become research hotspot. Majority of AMPs can disrupt the cell membrane of microorganisms, leading to the death of microorganisms. In this study, the AMP QUB-2852 was identified from the skin secretion of pelophylax nigromaculata …
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Chemical and physical methods of enhancing the percutaneous absorption of antimicrobial agents
… surface. Hence, in order to sterilise the skin, antimicrobial agents are required to penetrate across the skin and eliminate the bacteria residing at all depths. Chlorhexidine is an antimicrobial agent with the widest use for skin sterilisation. However, due to its poor permeation rate across the …
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QUB-1475: A novel bioactive peptide from the skin secretion of frog Hylarana Guentheri
As antimicrobial resistance has become a threat towards human health for decades, the demand for the development of an alternative, broad-spectrum antimicrobial agent has turned into increasingly essential. As a consequence, the emergence of the antimicrobial peptide (AMP) derived from the skin …
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Molecular epidemiology of the multidrug-resistant Escherichia coli sequence type 131-H30 lineage among U.S. children
… important pathogen implicated in rising rates of antimicrobial resistance among extraintestinal E. coli infections. H30 causes both community- and healthcare-associated infections, and is associated with resistance to several commonly used antimicrobial agents. This dissertation addresses several …
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Plant-Pathogen Interactions Associated with Wasting Disease in the Tropical Seagrass Thalassia testudinum.
… associated with the oxidative burst is simply an antimicrobial agent or a signaling molecule that will initiate programmed cell death (PCD) and lead to the hypersensitive response (HR), a process not yet characterized in seagrasses. ROS accumulation was found to increase around the lesion as the …
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Identification and functional study of a novel antimicrobial peptide, QUB-2014, from the skin secretion of the frog, Phyllomedusa tomopterna
… various bioactive compounds. Among these, antimicrobial peptides (AMPs) are vitally important as they protect amphibians from the attack of microorganisms. Some studies showed that AMPs are considered the new potential antibiotic candidates for humans and these molecules are also beneficial …
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Efficacy of high pressure processing in combination with chemical preservatives for the reduction of Escherichia coli O157:H7 and Salmonella in apple juice and orange juice
… a subsequent study using HHP in conjunction with antimicrobials (dimethyl dicarbonate [DMDC] at 62.5 and 125 ppm, hydrogen peroxide at 150 and 300 ppm, cinnamic acid, potassium salt at 125 and 250 ppm, potassium sorbate [KS] at 500 and 1000 ppm and sodium benzoate [NaB] at 500 and 1000). For both …
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Improving antibiotic activity by manipulating bacterial reactive oxygen species metabolism
… then describe work indicating that an ancient antimicrobial agent, silver salts, can also increase endogenous ROS production and potentiate the activity of multiple antibiotic classes. Furthermore, I show that silver salts can increase the outer membrane permeability of a Gram-negative …
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Compliance with surgical antibiotic prophylaxis guidelines: a prospective descriptive study at a tertiary level hospital in Cape Town, South Africa
… infection (SSI) by administering an appropriate antimicrobial agent perioperatively. However, SAP may be associated with adverse effects and incurs added costs. The primary objective of this prospective study is to establish whether clinicians are adhering to existing perioperative antibiotic …
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ASSESSING THE GENOTOXICITY OF TRICLOSAN IN TADPOLES OF THE AMERICAN BULLFROG, LITHOBATES CATESBEIANUS.
… assessing the genotoxicity of the widely used antimicrobial agent Triclosan to American Bullfrog tadpoles. Lithobates catesbeianus tadpoles were reared in glass aquaria containing ultra-high purity water and were dosed with nominal concentrations of 2.3 µg/L, 23 µg/L, and 230 µg/L Triclosan, …
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Effect of silver nanoparticles on planktonic and biofilm cell growth
… used nanoparticles, most notably serving as an antimicrobial agent for sanitization and medical purposes. Despite of their widespread use, little was known about the environmental effect of silver nanoparticles. This research focused on the impact of AgNPs on planktonic (e.g., free swimming) and …
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