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Showing 1 to 11 of 11 for “"antifreeze glycoproteins"”.
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Antifreeze Glycoproteins of Two Unrelated Polar Fishes: Gene Structure, Organization and Evolution
The AFGPs of the northern cods are also encoded by a family of polyprotein genes in which multiple AFGP coding sequences linked in tandem by small cleavable spacers Args or Arg-Ala-Ala-Arg's. However, the northern cod AFGP genes show no sequence identity with trypsinogen gene, indicating …
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Freezing Avoidance of Antarctic Fishes: The Role of a Novel Antifreeze Potentiating Protein and the Antifreeze Glycoproteins
AFPP is a 15.5 kDa protein with an unbiased amino acid composition. It was found in all the Antarctic notothenioid fishes examined, at different concentrations. It was most abundant in the shallow water fishes swimming in ice-laden water, but was present at concentrations ten fold less in the …
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Unnatural glycopeptides with application on cancer research
… cancer: mucins, such as mucin-1 (MUC1), and antifreeze glycoproteins. Concerning the first mentioned class, mucins are a family of O-glycoproteins with high molecular weight that serve as cell-surface receptors and sensors. Notably, aberration in the glycosylation of this tandem repeats is …
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Comparative antifreeze trait analyses of Antarctic and temperate sister species pairs shed light on tempo of adaptive trait loss under relaxed selection
… Southern Ocean survive by having evolved antifreeze glycoproteins (AFGP). Over evolutionary time several lineages have escaped the isolated frigid Southern Ocean to north of the Antarctic Polar Front and successfully colonized temperate sub-Antarctic waters. This study investigates the …
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Behavioral freeze avoidance in an Antarctic fish
… primarily by the action of their blood-borne antifreeze glycoproteins (AFGPs). AFGPs arrest the growth of environmental ice crystals that enter the fish, thereby preserving the body fluids in liquid state. AFGPs are ubiquitous in all adult Antarctic notothenioids examined, except for an early …
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Hemmung der Eisrekristallisation in wässrigen Lösungen durch Antigefrierglykopeptide
Antifreeze proteins (AFP) inhibit the growth of ice crystals and, thus, play an important role in the survival of many organisms at temperatures below the freezing point. But many aspects of the mechanism of action are still not understood, especially for antifreeze glycoproteins and glycopeptides …
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Creating sense from non-sense DNA: de novo genesis and evolutionary history of antifreeze glycoprotein gene in northern cod fishes (gadidae)
… Seven gadid species are known to have evolved antifreeze glycoproteins (AFGPs) that enable their survival from inoculative freezing by environmental ice in frigid Arctic and sub-Arctic waters. AFGPs protect the fish from freezing death by binding to ice crystals and arresting ice growth within …
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The influence of environmental temperature on the thermal tolerance of Antarctic notothenioid fishes
… and limited by their circulating levels of antifreeze proteins (AFPs). To investigate the differences in freeze avoidance between these regions’ endemic ichthyofaunas blood serum freezing points were measured in 11 of the 14 species of the Antarctic icefishes (family Channichthyidae). While …
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Analysis of the antifreeze glycoprotein containing genomic locus in the Antarctic notothenioid fish dissostichus mawsoni
… radiation was linked to the evolution of antifreeze glycoproteins (AFGPs). High blood levels of AFGPs (25 to 35 mg/ml) lower their freezing point a few tenths of a degree below that of seawater (-1.86oC) and are a vital part of their freeze avoidance strategy. The AFGP gene evolved from a …
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Effect of environmental temperature on Antarctic fish antifreeze protein activity and concentration
… attributable in part to the evolution of blood antifreeze proteins (AFPs) that adsorb to the surface of internalized ice crystals and inhibit their growth. The non-colligative depression of the blood serum freezing point can contribute enough protection to prevent freezing down to or below the …