Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 107 for “"antidepressants"”.
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Antidepressants, bioenhancements, and the ethics of self-respect
Antidepressants and bioenhancement technologies raise special concerns - both for those who use them and those who don't - about who we are and how we should treat ourselves. In this dissertation, I confront these concerns by asking and answering two ethical questions about different forms of …
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Mood and anxiety disorders: Comorbidity and implications for treatment with antidepressants
Contains fulltext : 18970.pdf (Publisher’s version ) (Open Access)
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Safety and Effectiveness of Antidepressants in Medicaid-Enrolled Pediatric Bipolar Depression
… medication regimens includingmood stabilizers, antidepressants, and antipsychotics for treating bipolar depression in adults is well established (Lin et al., 2006), similar treatment guidelines for bipolar depression in younger populations are unavailable. Efficacy of different classes of …
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Analysis of miRNome expression profile in hippocampus of rats treated with antidepressants
… drugs action, such as mood stabilizers and antidepressants (ADs). Aim of the studies presented was to analyze whether modulation of hippocampal miRNome could be part of the mode of action of different ADs, fluoxetine, desipramine and agomelatine. Moreover, in order to assess the time course …
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The use of low dose tricyclic antidepressants at Heideveld Community Health Centre
… To describe how doctors are prescribing low dose antidepressants at Heideveld Community Health Centre. OBJECTIVES: 1. To determine how many patients are being prescribed low dose antidepressants at Heideveld Community Health Centre. 2. To see what sort of dosages are being prescribed as low dose …
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Microbial and Immune Signatures of Stress and Antidepressants Across Sex and Generations
The gut, brain, and immune system form an integrated and dynamic network that shapes development and health outcomes across the lifespan. Increasing evidence indicates that this axis is highly sensitive to stress exposure, displays robust sex-dependent properties, and may transmit biological …
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Comparative Effectiveness of Second Generation Antidepressants on Cognition and Dementia in the Elderly
… comparative effectiveness of second generation antidepressants classes on cognition in elderly nursing home residents with depression, and 2) to evaluate the comparative effectiveness of second generation antidepressants classes on dementia in elderly nursing home residents with depression. …
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Early environments and neurobehavioural programming: Therapeutic actions of antidepressants. Neurobehavioural programming during development.
… 2004), and have investigated the potential for antidepressants to alter the influence of gestational stress on maternal behaviours and depressive-like response, and whether or not the offspring¿ are modified by maternal treatment with ant-depressants. Approximately 140 time-mated, lister hooded …
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Prevalence and effects of antidepressants during pregnancy on infant outcomes among women in Iceland
… Latest studies have shown that the use of antidepressants during pregnancy is increasing. Therefore, the aim of this study was to examine the prevalence and effects on infant outcomes associated with antidepressant use during pregnancy in Iceland. Method: The research design of the study …
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The Effect of Antidepressants on Cardiovascular Morbidity and Mortality: A Population-based Cohort Study
Background: Antidepressants such as selective serotonin reuptake inhibitors (SSRIs) and venlafaxine have the potential to exert beneficial effects on the heart via serotonin mediated antiplatelet activity. However, previous evidence regarding the cardiovascular effects of these agents has been …
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Effects of Second-Generation Antidepressants on Cognitive Functions: A Systematic Review and Meta-Analysis
Objectives: Second-generation antidepressants are currently the first-line of treatment for depression and are widely used. The aim of this study was to determine the effects on cognition by second-generation antidepressants through a systematic review and meta-analysis of recent scientific …
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Neurodevelopmental and Behavioral Consequences of Serotonin System Disruption via Early Life Exposure to SSRI Antidepressants
Selective serotonin reuptake inhibitor (SSRI) antidepressants are widely prescribed to pregnant women suffering with depression, although the long-term impact of these medications on exposed offspring are poorly understood. Perinatal SSRI exposure alters human offspring's neurodevelopment and …
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The glutamate hypothesis of depression: the effect of stress and glucocorticoids on glutamate synapse and the action of antidepressants
… induced by acute stress is prevented by chronic antidepressants (ADs). Additional studies have also shown that ADs can regulate glutamate transmission through glutamate receptors; reducing the function of NMDA receptors, potentiating the function of AMPA receptor and affecting different subtypes …
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Medicating the Crisis: Investigating the Links Between Precarious Employment, Mental Health Issues, and the Reliance on Antidepressants as Treatment
… commodity-based interventions, specifically antidepressants, in response to illness experiences – where dis-ease becomes disease. My primary method is a theoretical analysis of capitalist commodity production, the social process of medical knowledge production, medicalization, and development …
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Effect of antidepressants and adolescent stress on catecholamine transmission in the rat bed nucleus of stria terminalis (BNST): a microdialysis study
Rationale: Antidepressants include a relatively wide spectrum of drugs that increase the synaptic concentration of monoamines, mostly through neurotransmitter reuptake blockade. The bed nucleus of stria terminalis (BNST) is considered a relay station in mediating the activation of stress response …
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An In Vitro Characterization of the Raphe Nucleus and the Effects of SSRIs on Synaptic Neurotransmission
Antidepressants are traditionally used in the treatment of depression. While these drugs rapidly inhibit the reuptake of neurotransmitters in the synaptic terminal by blocking the serotonin and norepinephrine transporters, clinical efficacy can take several weeks. This phenomenon implies that …
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On The Future Of Antidepressant Treatments: Targeting Neurotrophic Factors And Plasticity
… have shortcomings. Despite evidence that current antidepressants elevate synaptic monoamine levels within hours of administration, these drugs require four to six weeks of daily administration before symptom relief appears. Furthermore, approximately half of patients taking typical antidepressants …
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