Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 53 for “"anticoagulation"”.
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Complications of anticoagulation in pregnant women with mechanical heart valves
Includes abstract. Includes bibliographical references.
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Citrate kinetics during regional citrate anticoagulation in extracorporeal organ replacement therapy
Regional citrate anticoagulation is an important alternative anticoagulation method for haemodialysis patients at high risk of bleeding. In order to better define the optimal dose of citrate and calcium infusion and to identify patients at risk for side effects, the kinetics of citrate and calcium …
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Economic Evaluation of Anticoagulation with Bivalirudin vs. Heparin during Pediatric Extracorporeal Membrane Oxygenation
… causes of cardiac or respiratory failure. Anticoagulation is required during ECMO to prevent formation of blood clots as the body is exposed to foreign materials of the ECMO circuit. The delicate balance between bleeding and clotting can be difficult to achieve in pediatric patients who …
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Duration of oral anticoagulation in first-episode idiopathic deep vein thrombosis: A Markov decision analysis.
… months, twelve months, two years, and lifelong anticoagulation for first episode idiopathic DVT. Secondary objectives were to assess quality of life for patients on warfarin therapy for DVT and for patients with post-thrombosic syndrome. A third objective was to determine if quality of life for …
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Real-world Pharmacological Anticoagulation and Clinical Outcomes of Venous Thromboembolism in Adults with Sickle Cell Disease
… the treatment patterns of pharmacological anticoagulation in adults with SCD was studied by using a retrospective, repeated cross-sectional design. The results may contribute to the optimal selection of regimens or dosing and informed decision making on anticoagulant utilization in routine …
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Oral anticoagulation treatment in atrial fibrillation - To bleed or not to bleed, that is the question
… ratio (INR). Monitoring and tight control of anticoagulation treatment reduces the risk of both thrombosis and bleeding. The time in therapeutic range (TTR) has been validated as a quality indicator of the anticoagulation treatment given, correlating inversely to complication frequencies. The …
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The nature of leukocytic response to mouse mammary tumor implants in C3H/HeJ mice with and without anticoagulation
… response to tumor implants with and without anticoagulation.</p>
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What is the efficacy of withholding perioperative anticoagulation bridging in patients with atrial fibrillation undergoing elective invasive procedures?
… cardioembolic events, necessitating chronic oral anticoagulation in most patients. The efficacy of heparin bridging during temporary interruptions of oral anticoagulants compared to no bridging in the perioperative setting remains unclear. This systematic review aims to investigate the efficacy of …
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Haemorrhage and Other Complications in Pregnant Women on Anticoagulation for Mechanical Heart Valves; a Prospective Observational Cohort Study
Objective: To document maternal and foetal morbidity and mortality in anticoagulated, pregnant patients with mechanical heart valves until 42 days postpartum. Methods: In a tertiary single-centre, prospective cohort, 178 consecutive patients at the cardiac-obstetric clinic were screened for …
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Increasing Patient Satisfaction and Decreasing Hospital Readmission Due to Deep Venous Thrombosis by Providing Anticoagulation Education for Orthopedic Patients
… <p>The aim of this project is to improve anticoagulation education for orthopedic patients to increase patient satisfaction. The microsystem for this project is a medical-surgical (MS), 50-bed unit in a medium size hospital. Because orthopedic patients are at high risk to develop DVT …
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Poor anticoagulation control in patients taking warfarin at a tertiary and district-level prothrombin clinic in Cape Town, South Africa
… and secondary prevention of thromboembolism. For anticoagulation efficacy, the international normalised ratio (INR) needs to be within the therapeutic range for at least 65% of time on warfarin. Objectives. To describe INR control in patients on long-term warfarin and identified predictors of good …
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Does engaging with an interactive adherence intervention improve time in therapeutic range compared to receiving an education intervention alone, among patients anticoagulated with warfarin in Cape Town, South Africa?
Background: Warfarin is the mainstay of oral anticoagulation in South Africa. There is wide variability between individual dose requirements. Regular International Normalised Ratio (INR) monitoring to guide dosing is required. Maintaining INR in therapeutic range is important for efficacy and …
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Early Identification and Intervention in Patients with Atrial Fibrillation Using an Implantable Cardiac Monitor to Significantly Improve Guideline-Based Anticoagulation Therapy in an Outpatient Cardiology Clinic
… monitor to significantly improve guideline-based anticoagulation therapy.</p> <p>Methods: A retrospective database from an outpatient clinic in southern California was analyzed in this non-experimental study design; it comprised routinely-collected data on patients with ICMs implanted between June …
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Profile and anticoagulation outcomes of patients on warfarin therapy in an urban hospital in Cape Town: a review of records of patients attending Victoria Hospital, Cape Town, South Africa
… nine countries, South Africa had the poorest anticoagulation control with warfarin. This study showed that 86% of patients on warfarin therapy in the country have their mean time in therapeutic range below target. This was an indication of a very poor warfarin control in South Africa .The …
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Novel Sulfated 4-Hydroxycinnamic Acid Oligomers as Potent Anticoagulants
… conditions creates a huge need for anticoagulation therapy. Thrombin and factor Xa have been prime targets for regulation of clotting through the direct and indirect mechanism of inhibition. This work investigates chemo-enzymatically prepared oligomers of 4-hydroxycinnamic acids …
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Personalised warfarin dosing in children after congenital heart surgery using the model-based approach
Oral anticoagulation with warfarin represents a major challenge to successful drug therapy in children. The aims of this study was to investigate the implementation in routine clinical practice, personalised warfarin dosing using a PK/PD model, in children after congenital heart surgery and to …
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Shared Decision-Making to Improve Uptake of and Adherence with Oral Anticoagulation Therapy for Stroke Prevention in Patients with Atrial Fibrillation: Initial Clinical Evaluation of a Web-Based Patient Decision Aid
… a shared decision-making intervention to support anticoagulation decisions in AF care. The research was conducted in three phases. First, a retrospective cohort study utilized administrative health data to identify the predictors of nonpersistence to OAC therapy among people diagnosed with …
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Polymeric Transcatheter Heart Valves
… mechanical surgical valves require life-long anticoagulation. Polymeric transcatheter aortic valve insertion (TAVI) is proposed as a solution to provide long-term durability without the need for anticoagulation. A manufacturing method involving the spray coating of polyurethane solutions onto …
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Pharmacological Interventions in Atrial Fibrillation
… be focusing on rhythm control, rate control, anticoagulation and interventional treatment.
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