Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 148 for “"antibody response"”.
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Antibody Response to Lipopolysaccharide of Salmonella Typhimurium
… has a profound effect on the host immune response.
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Signals for B cell activation in antibody response
… antigen on FDC is present in the form of antigen-antibody immune complex, GC B cells are expected to have to compete with antibody to get access antigen. Initially this antibody will be of low affinity. However, during the course of an immune response, this affinity may increase. We have tested …
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Optimizing vaccine dosing kinetics for stronger antibody response
… understanding of how innate and adaptive immune response systematically emerge and evolve. Immune response is comprised of dynamic events that require many components to cooperate collectively in a manner that spans a range of scales. These characteristics make it hard to predict mechanisms for …
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Human Antibody Response to Flaviviruses and SARS-Coronavirus-2
… ever greater. Understanding the adaptive immune response to these pathogens will expand basic understanding of viral immunity mechanisms and can help inform vaccine and therapeutic development. This thesis describes the characterization of the human antibody response to several important viral …
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Development and Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1
A neutralizing antibody response of sufficient potency, magnitude and duration is considered an important part of a successful HIV vaccine. A better understanding of the factors associated with the development of broadly neutralizing antibody responses (effective against a wide range of clinical …
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Genomics-Based Analysis of Antibody Response to Sheep Red Blood Cells in Chickens
Immune response provides vertebrates an important mechanism to fight pathogens and to reduce the incidence of diseases. Defining the molecular basis of antibody response may facilitate genetic improvement in the immune response of animals to pathogens. For almost 4 decades, antibody titers in …
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Reproductive Soundness and Egg Quality in Chickens Selected for Low and High Antibody Response
… were selected for high (HAS) or low (LAS) antibody response to sheep red blood cells. The focus of this thesis was to investigate correlated responses in reproductive soundness and egg quality resulting from that selection. Forty-five hens and 25 roosters from each antibody line were used. …
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Evaluating the neutralizing antibody response to HIV-1 membrane proximal external regional; Implications for vaccine design
Inducing broadly neutralizing antibodies targeting the HIV-1 envelope is thought to be crucial for developing an effective vaccine. The Membrane Proximal External Region (MPER) within the HIV- 1 gp41 envelope is a promising vaccine target. The MPER is highly conserved, functionally constrained, …
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Antibody Response to Trypanosoma Cruzi During the Course of Infection in Mice Held at Elevated Environmental Temperature
… immune responsiveness in infected mice. The antibody response to heterologous antigen has been demonstrated to be greatly enhanced in infected mice held at elevated temperature. However, the parasite-specific antibody response was reported to be lower in infected mice maintained at 36°C than …
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Surface Coat Replacement Dynamics and Antigen Glycosylation in T. Brucei Influence Evasion of the Host Antibody Response
… During infection, the VSG coat elicits a robust antibody response, but the parasite escapes antibody-mediated clearance by repeatedly accessing its large genomic VSG repertoire and switching expression to antigenically distinct VSGs. Much of our knowledge of the process of VSG switching and the …
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A study of genital human papillomavirus (HPV) infection and antibody response in heterosexually active South African couples
This study constitutes the first report on type-specific human papillomavirus (HPV) concordance and transmission in heterosexually active couples that are human immunodeficiency (HIV)-seronegative, HIV-seropositive or HIV-discordant and in which 71% of female participants have normal cervical …
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ANALYSIS OF HERPES SIMPLEX VIRUS ICP0 FUNCTION AND THE ANTIBODY RESPONSE TO A LIVE HSV-2 ICP0- MUTANT VACCINE
… of ICP0 but instead focus on characterizing the antibody response elicited by a highly protective HSV-2 ICP0- vaccine that was developed in our lab. Specifically, despite the belief that virion glycoproteins such as glycoprotein D (gD-2) are the dominant antigens of herpes simplex virus 2 (HSV-2) …
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Antibody Response to Heat Shock Proteins of Trypanosoma Cruzi and Histopathology in Mice Infected and Maintained at Elevated Environmental Temperature
… parasite-specific and non-specific immune responses. The present study was designed to determine whether heat shock proteins (hsps) of the parasite might be playing a role in this phenomenon. In the first set of experiments antibody responses to parasite hsps were analyzed using metabolic …
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Antibody Response of the Fetus and Adult Equine to Venezuelan Equine Encephalomyelitis Virus (vee-Tc-84): Immunoglobulins G(a and B), M, and T
Made available in DSpace on 2014-12-14T13:28:17Z (GMT). No. of bitstreams: 1 7726716.pdf: 1935693 bytes, checksum: 35542f06348eb82bc4886f1bb2e5a989 (MD5) Previous issue date: 1977
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Effects of copper and selenium on antibody response, weight gains and blood parameters in beef calves grazing high or low endophyte (Acremonium coenophialum) tall fescue (Festuca arundinaceae, Schrep)
… hematological evaluations, and serum antibody response (IgG and IgM) to a synthetic antigen, TGAL, as measured by ELISA.
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