Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"antibiotic susceptibility testing"”.
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A multiplexed microfluidic platform for antibiotic susceptibility testing
Antibiotic susceptibility testing represents a key first step for determining therapeutic regimens to treat bacterial infections. Current technologies are slow and cumbersome, require large sample volumes for analysis, have poor detection sensitivity and limited combinatorial capabilities. These …
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A Novel High Throughput Platform for Assessing Bacterial Growth and Morphology Enables Rapid Antibiotic Susceptibility Testing
The alarming rise in antibiotic resistance necessitates a better understanding of the mechanisms of antibiotic action and calls for tools that enable rapid antibiotic susceptibility testing (AST). This thesis introduces the Multipad Agarose Plate (MAP): an innovative platform that can perform rapid …
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Developing a microfluidic-microwave platform for real-time, non-invasive and sensitive monitoring of pathogens and antibiotic susceptibility testing
… quality of service is infection diagnosis and antibiotic susceptibility testing. Due to issues with infection diagnosis and outdated antibiotic susceptibility testing (AST) methods, physicians are over-prescribing broad-spectrum antibiotics. This coupled with patients’ non-compliance in …
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Assessment of antibiotic resistance phenotypic patern in some commensal bacteria isolated from meat and dairy products
This study investigated the pattern of antibiotic resistance in some commensal bacteria isolated from meat and dairy products. This study is important because, antibiotics resistance has become a serious public health concern with economic and social implications throughout the world. The use of …
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Technological advancements towards paper-based biomolecular diagnostics
… the development of a paper-based diagnostic for antibiotic susceptibility testing.
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New Tools for Diagnosis and Treatment of Bacterial Infections
The excessive and inappropriate use of antibiotics has contributed to the spread of antibiotic resistance, a serious challenge the global health industry is facing. To help preserve the effectiveness of current commercially available therapies, timely, accurate and user-friendly diagnostic tools …
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Food safety knowledge, attitude and practices of food handlers at the university teaching hospital in Lusaka.
… (39) S. aureus isolateswere then subjected to antibiotic susceptibility testing. The antibiotic susceptibility test revealed that the isolates had high resistance to antibiotics commonly used in both human and animal medicine especially to nalidixic acid and chloramphenicol. The study …
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Food safety knowledge, attitude and practices of food handlers at the university teaching hospital in Lusaka.
… (39) S. aureus isolateswere then subjected to antibiotic susceptibility testing. The antibiotic susceptibility test revealed that the isolates had high resistance to antibiotics commonly used in both human and animal medicine especially to nalidixic acid and chloramphenicol. The study …
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Phenotypic and molecular characterization of coagulase negative staphylococci from pigs and humans in Lusaka province, Zambia.
… health implications of CoNS as they can transfer antibiotic resistance genes and cause infections such as urinary tract infections, endocarditis and surgical site infections. While CoNS have been primarily studied in hospital environments, data from community settings, particularly in Africa, …
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Phenotypic and molecular characterization of coagulase negative staphylococci from pigs and humans in Lusaka province, Zambia.
… health implications of CoNS as they can transfer antibiotic resistance genes and cause infections such as urinary tract infections, endocarditis and surgical site infections. While CoNS have been primarily studied in hospital environments, data from community settings, particularly in Africa, …
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Detection of Vancomycin resistant Enterococci from clinical specimens at University Teaching Hospitals
… species difficult. Resistance to glycopeptide antibiotics, especially Vancomycin is of special concern as Vancomycin resistant genes are encoded on plasmids which can be transferred to other organisms. Currently, there is no documented information relating to the occurrence and resistance genes …
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Detection of Vancomycin resistant Enterococci from clinical specimens at University Teaching Hospitals
… species difficult. Resistance to glycopeptide antibiotics, especially Vancomycin is of special concern as Vancomycin resistant genes are encoded on plasmids which can be transferred to other organisms. Currently, there is no documented information relating to the occurrence and resistance genes …
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Urinary tract infection in children at Victoria Hospital, a district hospital in Cape Town, South Africa
… 24-48 hours, necessitating initiation of empiric antibiotic therapy. Recent data on the epidemiology and antibiotic susceptibility profile of community-acquired bacterial UTI in children in Cape Town is lacking. Objectives: To describe the clinical profile and organisms including antibiotic …
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Identification of potential pathogens of pneumonia in sputum samples from adult patients at the University Teaching Hospital in Lusaka
… pneumonia in adult patients and determine their antibiotic susceptibility patterns at the University Teaching Hospital in Lusaka. Materials and Methods: This was a cross-sectional study carried out from March 2014 to August 2014. A total of 312 sputum samples from adults suspected of pneumonia …
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Bacteriology and antibiotic sensitivity patterns of urine in urology patients with indwelling urinary catheters at the University Teaching Hospital in Lusaka, Zambia.
… has been reported to be upto 35%. The growing antibiotic resistance amongst the uropathogens isolated from CAUTI makes it difficult for its management.In Zambia,prolonged catheter use is a burden particularly in patients awaiting definitive surgery,the elderly and socioeconomically …
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Identification of potential pathogens of pneumonia in sputum samples from adult patients at the University Teaching Hospital in Lusaka
… pneumonia in adult patients and determine their antibiotic susceptibility patterns at the University Teaching Hospital in Lusaka. Materials and Methods: This was a cross-sectional study carried out from March 2014 to August 2014. A total of 312 sputum samples from adults suspected of pneumonia …
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Ornithobacterium hominis isolates from a South African birth cohort
… African O. hominis isolates were determined and antibiotic susceptibility determined. For whole genome sequencing, DNA was extracted, assessed for quality, and sequenced using the Oxford Nanopore technologies platform. Genomes were assembled using an in-house bioinformatic pipeline. Genomes were …
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Environmental and biological drivers of bacterial and antimicrobial resistance carriage by house flies (Musca domestica L.)
… transmission and persistence due to the high antibiotic use, abundant bacteria sources and large house fly populations at these facilities. The first objective of this study was to assess biological and environmental drivers of bacterial abundance, as well as trends of AMR for suspected …
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Microbial, metabolic and molecular determinants of neonatal mortality in the rural areas of Limpopo Province, South Africa: umblical cord blood metabolomic profile and bacterial anaysis and their association with perinatal complications
… analysis (through 16S rRNA PCR assay and antibiotic susceptibility test profiling) and metabolomic profiling of umbilical cord blood to identify potential biomarkers for perinatal complications. METHODS: A cross-sectional study utilizing purposive sampling was conducted at selected …
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Proteomic comparison of Amoxicillin resistant and susceptible periodontal Provotella Intermedia and Provotella Nigrescens clinical isolation with Matrix-Assisted Laser Disportion Ionization Time-Of-/flight mass spectrometry
… P. nigrescens may exhibit resistance to β-lactam antibiotics prescribed in periodontal therapy via expression of β-lactamase enzymes. Conventional methods of in vitro antibiotic susceptibility testing entail cultivation of targeted bacterial species, with evaluations of whether or not the organism …
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