Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"antibiotic stewardship"”.
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Antibiotic Stewardship Program Development in a Rural Urgent Care Clinic
Problem: The misuse and overuse of antibiotics are critical factors leading to antimicrobial resistance (AMR) and infections becoming harder to treat. Most antibiotics are prescribed in outpatient settings for upper respiratory infections (URIs), yet these infections are commonly caused by viruses …
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Providing an evidence base for antibiotic stewardship for midwives in the Kabarole district of Uganda : a modified action research study
… in the Kabarole district of Uganda about antibiotic resistance and antibiotic stewardship. Antibiotic resistance is fast becoming a threat to the health of the global population. Antibiotic resistance arises when an antibiotic becomes ineffective at treating a bacterial infection which it …
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Strengthening Antibiotics Stewardship At Mowbray Maternity – Neonatal Unit
… hand hygiene (HH) practices and adherence to antibiotic stewardship principles in the neonatal unit at Mowbray Maternity Hospital (MMH). Study design: Mixed method observational study was done at MMH. A point of prevalence survey to assess antibiotic stewardship and HH audits were conducted …
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A mixed methods exploration of antibiotic prescribing and stewardship
Unnecessary prescribing of antibiotics for viral respiratory tract infections is common and contributes to emerging antibiotic resistance and patient morbidity and mortality. Interventions aimed at promoting judicious use of antibiotics, such as prescribing guidelines, are often ineffective. …
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Learning treatment policies for empiric antibiotic prescription
Rising antibiotic resistance rates pose a serious public health threat and are largely driven by overuse and inappropriate use of antibiotics. Antibiotic stewardship efforts have been established around the world to improve prescription practices, but further optimization of antibiotic usage is …
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Evolutionary Trade-offs Between Antimicrobial Resistance and Virulence in Pseudomonas aeruginosa
Antimicrobial resistance (AMR) threatens antibiotic efficacy, yet its evolutionary consequences for pathogen virulence and growth remain poorly resolved. This thesis addresses this gap using Pseudomonas aeruginosa, a multidrug-resistant pathogen capable of both acute toxin-mediated and chronic …
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Reducing the Use of Antibiotics for Viral Upper Respiratory Infections in the Primary Care Setting
AbstractProblem: Antibiotic resistance leads to 700,000 deaths worldwide each year. Antibiotic overuse is a leading cause of this resistance and is particularly prevalent in patients with upper respiratory symptoms, even though most URIs are viral. Literature Review: Antibiotic overuse could be …
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Outcomes of patients undergoing lung resection for drug-resistant TB and the prognostic significance of pre-operative positron emission tomography/computed tomography (PET/CT) in predicting treatment failure
… practice and underscore the need to support antibiotic stewardship strategies in TB-endemic settings.
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Identification and characterisation of cephalosporins and carbapenem-resistant Klebsiella pneumoniae isolates from Misrata, Libya
… and 13 (15.2%) were susceptible to all antibiotics except ampicillin. OXA-48 was the only carbapenemase detected, with SHV, TEM and CTX-M group 1 found in almost all carbapenem and cephalosporin resistant K. pneumoniae. Rep-PCR analysis revealed multiple clones and some K. pneumoniae …
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Implementation of an Outpatient Antimicrobial Stewardship Program to Reduce Fluoroquinolone Overprescribing at a Veterans Affairs Academic Medical Center
… often overprescribed in outpatient settings, and antibiotic stewardship programs designed to prevent overuse are not well described. The primary purpose of this study was to evaluate the change in overall and appropriate fluoroquinolone prescribing rates by primary care providers at a Veterans …
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Novel Diagnostic Methods for Rapid Detection and Identification of Bacterial Infections in Bovine Mastitis
… potentially unnecessary or non-effective antibiotic treatment. In the dairy industry, speeding up this diagnostic process would facilitate considerable improvements in antibiotic stewardship. This thesis describes the development of three methods developed for the rapid diagnosis of …
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Bugs, Drugs and Data: Antibiotic Resistance, Prevalence and Prediction of Bug-Drug Mismatch using Electronic Health Records (EHR) Data
… and modifiable category of inappropriate antibiotic therapy (IAAT) that increases adverse outcomes for patients and drives overall antibiotic resistance (AR). Surveillance of baseline AR, emerging trends in resistance among priority bacterial pathogens and prevalence of BDM with respect to …
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Neonatal Sepsis And Antibiotic Sensitivity Patterns At A South African Tertiary Nursery – Evolution Over A 15 Year Period
… in babies. The causative pathogens and their antibiotic susceptibility patterns should be monitored so that treatment regimens can be adjusted to maintain efficacy and avoid selection of resistant organisms. Objectives To compare the incidence of culture positive neonatal sepsis; and to …
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Burden, Etiology and Control of Hospital Acquired Infections in Intensive Care Units in Vietnam
… A point prevalence survey (PPS) of HAI and antibiotics use was conducted monthly at 15 ICUs of 14 tertiary and provincial hospitals across Vietnam from October 2012 to September 2013. Subsequently an observational study focused on ventilator associated pneumonia (VAP) and ventilator …
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Perioperative antibiotic practices amongst Otorhinolaryngologists (Ear, Nose & Throat Surgeons) in South Africa
Background: The primary goal of perioperative antibiotics is to reduce the rate of surgical site infections (SSI); however, in certain surgical procedures, the use of perioperative antibiotics has been shown to have no impact on the rate of SSI. Inappropriate use of antimicrobials not only comes at …
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Antibiotic use in a level three NICU in South Africa
Background: Antibiotics are the most commonly used medications in the neonatal intensive care unit, and when used appropriately, can be lifesaving in the NICU. However, their inappropriate use has been found to be associated with certain adverse effects like Late Onset Sepsis, Necrotizing …
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Antibiotic Resistance Profiles and Population Structure of Healthcare-associated and Community-associated Staphylococcus aureus isolated in Fort Portal, Western Uganda
… required to inform evidence-based improvement of antibiotic stewardship measures in the local area.This study focused on the evaluation of Staphylococcus aureus, a commensal bacterium carried by roughly 30% of the human population commonly in the nasopharynx and/or on skin. S. aureus also acts as …
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Educational Program For Caregivers Of Children With Tympanostomy Tube Otorrhea: Impact On Caregiver Self-Efficacy And Clinical Outcomes
<p>There is an overuse of oral antibiotics and acute care visits conducted to treat children with uncomplicated tympanostomy tube otorrhea (TTO), a condition easily identified by the child’s caregiver who can then independently initiate treatment with ototopical antibiotic drops (TAD). Yet, some …
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Assessing the Impact of a Unit-Based Clinical Pharmacist on Antimicrobial Use in a Level I Trauma Center – A Pilot Study
… Harris Health System launched its antimicrobial stewardship program, through coordinated efforts of the infectious disease teams, internal medicine, critical care medicine, surgery, hematology/oncology, emergency medicine, microbiology/pathology, nursing, pharmacy, and infection …
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Midline Catheter Usage in the Neonatal Population
… and susceptibility to sepsis make them prone to antibiotic treatment. Lack of recommendations points to the need for evidence-based practices when selecting a vascular access device (VAD). Literature reviewed demonstrated that a midline catheter (MC) was an option for a VAD with neonatal …