Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 108 for “"antibiotic resistance genes"”.
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Antibiotic Resistance Genes in Marquette County Michigan's Wastewater
<p>Antibiotic-resistant bacteria evade standard treatments, increasing disease severity, patient morbidity, and mortality. Following exposure to an antibiotic, resistant bacteria survive and pass antibiotic resistance genes (ARGs) to their progeny cells. Few ARG studies have utilized wastewater …
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Detection of antibiotic resistance genes in gardening composts
… used for gardening. To evaluate the risk of antibiotic resistance and potential pathogens in composts, two homemade composts, eight commercially available composts, and one immature swine mortality compost were collected and analyzed by high-throughput quantitative polymerase chain reaction …
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Recovery of Antibiotic Resistance Genes From Agricultural Runoff
The reduced capacity of antibiotics to treat infections is one of the greatest health concerns that society faces. There is substantial evidence that links this reduced capacity with the widespread use of antibiotics in livestock production. Livestock can act as reservoirs of antibiotic resistance …
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Excretion of Antibiotic Resistance Genes by Dairy Calves
… used to evaluate the effect of milk replacer antibiotics on abundance of selected antibiotic resistance genes (ARG) in the feces. Calves were blocked by breed, gender, and birth order, and assigned to one of three treatments at birth. Treatments were control (containing no antibiotics in the …
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Domestic greywater systems: a potential reservoir of antibiotic resistance genes transfer
… however, has the potential to harbour residual antibiotics and pathogenic bacteria, thereby potentially supporting the growth and proliferation of antibiotic resistant bacteria. This study combined traditional microbiology tests with molecular biology to detect resistant microorganisms within …
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Fate of Antibiotic Resistance Genes During Anaerobic Digestion of Wastewater Solids
Bacterial resistance to antibiotics has become a worldwide health problem, resulting in untreatable infections and escalating healthcare costs. Wastewater treatment plants are a critical point of control between anthropogenic sources of pathogens, antibiotic resistant bacteria (ARBs), antibiotic …
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The location, expression and regulation of three antibiotic resistance genes in acinetobacter
Clinical isolates of Acinetobacter often exhibit resistance to many antibiotics, including the aminoglycosides and chloramphenicol. Yet very little is known about this resistance at the molecular level. A strain of Acinetobacter baumannii (strain SAK) was isolated from a tracheal aspirate; it is …
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Effect of wastewater colloids on membrane removal of microconstituent antibiotic resistance genes
Anthropogenically generated antibiotic resistance genes (ARGs) are considered emerging contaminants, as they are associated with a critical human health challenge, are persist independent of a bacterial host, are subject to transfer between bacteria, and are present at amplified levels in …
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Multi-site sampling and risk prioritization of antibiotic resistance genes in sewage environments
The spread of antibiotic resistance across human and environmental habitats is a global public health challenge. In this study, we investigate the public health relevance of antibiotic resistance found in wastewater by combining metagenomic sequencing of wastewater environments with risk …
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Developing a Computational Pipeline for Detecting Multi-Functional Antibiotic Resistance Genes in Metagenomics Data
Antibiotic resistance is currently a global threat spanning clinical, environmental, and geopolitical research domains. The environment is increasingly recognized as a key node in the spread of antibiotic resistance genes (ARGs), which confer antibiotic resistance to bacteria. Detecting ARGs in the …
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Integrative Metagenomic Approaches to Study Antibiotic Resistance Genes and Microbial Functions in the Preterm Infant Gut Microbiome
The widespread use of antibiotics has substantially improved clinical outcomes, particularly the survival of preterm infants. In neonatal intensive care units, antibiotics are frequently administered because these infants are at high risk of severe bacterial infections. However, early-life …
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Abundance of Antibiotic Resistance Genes in Feces Following Prophylactic and Therapeutic Intramammary Antibiotic Infusion in Dairy Cattle
Prophylactic and therapeutic antibiotic treatments have the potential to increase excretion of antibiotic resistance genes (ARGs) by dairy cattle through selection pressure on the gut microbiome. The objective of these studies was to evaluate the effect of cephapirin benzathine administered …
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Airborne Dissemination of Antibiotic Resistance Genes Near Farms and Effectiveness of Ionization Against Airborne Bacteria in a Classroom
… (1) dissemination of antimicrobial resistance in the environment and (2) ionization for disinfection of indoor air. Antimicrobial resistance (AMR) poses a significant threat to public health, exacerbated by the dissemination of antibiotic resistance genes (ARGs) in the atmosphere to …
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Metagenomic Analysis of Antibiotic Resistance Genes in the Fecal Microbiome Following Therapeutic and Prophylactic Antibiotic Administration in Dairy Cows
The use of antibiotics in dairy cattle has the potential to stimulate the development and subsequent fecal dissemination of antibiotic resistance genes (ARGs) in bacteria. The objectives were to use metagenomic techniques to evaluate the effect of antibiotic treatment on ARG prevalence in the fecal …
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The Role of Bacteroides Conjugative Transposons in the Spread of Antibiotic Resistance Genes, And, The Role of recA in DNA Damage Repair in Deincoccus Radiodurans
… for investigating the horizontal transmission of antibiotic resistance genes in the environment. The data presented in this thesis shows that an open genetic conduit exists between gram positive bacteria that reside in the intestinal lining of cows and gram negative bacteria that reside in the …
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Effect of Soil Type, Composting, and Antibiotic Use on Fate of Antibiotic Resistance Genes and Microbial Community Composition in Dairy and Beef Manure Applied Soils
… that this practice could affect the spread of antibiotic resistance genes (ARGs) from farm to fork. A microcosm-scale study evaluated the effect of prior antibiotic use (manure-based soil amendments generated from dairy and beef cattle with or without antibiotic administration), composting, and …
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Markerfreie transplastome Tabakpflanzen
… typically involves the stable integration of antibiotic resistance genes as dominant selectable markers. The potential spread of these genes through pollen release or to soil microbes via horizontal gene transfer is of considerable environmental concern. The use of chloroplast transformation …
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Combating biofilms and antibiotic resistance using synthetic biology
… source of morbidity and mortality. Biofilms and antibiotic resistance pose challenges to our future ability to treat bacterial diseases with antibiotics (1). Bacteria frequently live in biofilms, which are surface-associated communities encased in a hydrated extracellular polymeric substances …
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Change in the Structure of Soil Microbial Communities in Response to Waste Amendments
… C, energy, and nutrient supply, but also antibiotic resistance genes (ARG), antimicrobials, and a multitude of microbial species. This project seeks to primarily assess if there is a change in bacterial community structure in response to poultry litter amendments to pasture land across …
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Genotyping antibiotic resistance properties of escherichia coli and campylobacter jejuni associated with diarrhoea in young children in the Vhembe District
… of young children in Sub-Saharan Africa. While antibiotic resistance among enteric pathogens such as Escherichia coli (E. coli) and Campylobacter spp. is increasing, surveillance of antimicrobial resistance genes (ARG) is limited in Africa. The need for such studies in Africa was demonstrated by …
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