Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"anti-uPAR"”.
-
Evaluierung des Antibody Directed Enzyme Prodrug Therapy-Konzepts im Mammakarzinom- und Lymphom-Mausmodell
… dieser Arbeit war es ein neues Therapiekonzept Antibody Directed Enzyme Prodrug Therapy (ADEPT) in Tieren zu evaluieren. Damit sollte eine höhere Spezifität und Selektivität in der Behandlung von Tumoren erreicht werden. Dabei wurden ein orthotopes Mammakarzinom- mit MDA-MB-231-Tumorzellen in …
-
Preparation and Evaluation of Molecular Imaging Probes Targeting the Urokinase Plasminogen Activator System
… reported involved targeting the uPA receptor (uPAR) through the use of antibodies and bioorthogonal chemisty based on radiolabeled tetrazines and transcyclooctene (TCO) functionalized biomolecules. A new tetrazine synthon was developed that can be readily labeled with both 99mTc and 18F where …
-
The uPA receptor in ovarian cancer. Regulation by EGF and the estrogen responsive membrane receptor GPR30. Soluble uPAR in diagnosis and prognosis.
… the malignant phenotype, and the uPA receptor (uPAR) plays a central role in cell migration. We studied the role of EGF and estrogen on cell migration and uPAR expression in ovarian cancer cell lines. We also analyzed the diagnostic and prognostic value of cleaved forms of the uPAR in plasma …