Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"anti-obesity"”.
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Anti-Obesity Effects of Adipose-Targeting Resveratrol Nanocarriers
Obesity is an important public health issue in the United States. When energy intake exceeds expenditure, excess energy is stored in the form of fat in adipose tissue, and weight gain occurs. Since induced brown-like/beige adipocytes have the same thermogenesis and metabolic sink functions as …
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Institutionalization of anti-obesity messages in Chilean schools
… youth have serious problems with overweight and obesity (World Health Organization, 2014). It is estimated that 41% of students in Chile who entered secondary education in 2015 were overweight or obese (La Nación, 2015). Isolated effects have been obtained in Chilean governmental initiatives. …
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Metabolic profiling of cyanobacterial extracts using multivariate data analysis for their anti-obesity properties
Background. Obesity has become a major health issue worldwide. Progression of obesity has been linked to numerous of comorbidities such as coronary heart disease, heart failure, hypertension and diabetes mellitus. The urge for new anti-obesity drugs with less adverse effects is apparent. …
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Anti-Diabetic and Anti-Obesity Activities of Cocoa (Theobroma cacao) via Physiological Enzyme Inhibition
… levels caused by processing affect cocoa's anti-diabetic and anti-obesity bioactivities, such as inhibition of certain enzymes in the body. Polyphenol profiles, protein-binding abilities, presence of compounds termed oxidative polymers, and abilities to inhibit α-glucosidase, pancreatic …
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Identification of a Dual-Action Small Molecule with Potent Anti-diabetic and Anti-obesity Activity
… less than one in four patients treated with anti-diabetic drugs achieved the glycemic target. Thus, identifying more effective anti-diabetic drugs is still needed for improving glycemic control in T2D patients. Incretins are gut hormones that possess potent insulinotropic action, which have …
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Leishmanicidal, anti-inflammatory and anti-obesity properties of natural products from common medicinal and edible plants.
… that could be applied for solving leishmaniasis, obesity and type 2 diabetes. This research showed leishmanicidal natural compounds isolated from Cichorium intybus L. (Asteraceae), Cornus florida L. (Cornaceae), Eryngium foetidum L. (Apiaceae), which have been used traditionally as antiparasitic …
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Pharmacological characterisation of selective Y4 and dual Y2/Y4 receptor agonists: novel targets for putative anti-obesity therapies
The GIPIO (Gastrointestinal Peptides in Obesity) collaboration was set up with EU (FP7) funding in 2008, with the aim to develop a series of peptide analogues for the treatment of obesity. Based on the dual Y2/Y4 agonist, Obinepitide ([Q34]hPP), and the Y4 agonist, TM30339 (hPP2-36), novel peptides …
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Discontent with the weight-centred health paradigm: A critical examination of the charge against 'obesity'
Since the late 1990s, addressing the global obesity epidemic has been a key public health priority. Despite substantial resources dedicated to its curtailment, the epidemic persists, prompting scholars to re-examine the underlying mechanisms of prevailing anti-obesity efforts. Within this context, …
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Weighted Policymaking: Federal, State and Local Politics of Obesity
… or obese. The financial and societal costs of obesity shift this condition from a private to a public problem necessitating a collective solution and an understanding of it as a public policy issue. This dissertation approaches obesity from three perspectives: individual, state and federal. …
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Exploring New Zealand Honeydew Honey, Yacon Concentrate, and their Novel Food and Health Applications
… effects on the formation of acrylamide, their anti-diabetic and anti-obesity properties, and their anti-microbial properties. In Chapter 3, the physicochemical properties of NZHDH such as proximate composition, mineral, sugar, phenolic, and amino acid profiles, and antioxidant activity, were …
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Assessment of blue whiting protein hydrolysate bioactivities using cell culture models
… the BWSPHs tested exhibited satiating activity, antioxidant activity, immunomodulatory activity or anti-obesity activity as measured using specific cellular models. However, six BWSPHs did exhibit anti-diabetic activity in vitro, therefore, these six BWSPHs were prepared at semi-pilot scale and …
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Phytochemical and biological investigation of Lathyrus linofilius as a possible treatment in diabesity
… cases. Therefore, there is a need for improved anti-diabetic drugs with fewer sideeffects to enhance patient compliance and to control blood glucose levels more tightly.Natural products and plants in particular, offer an alternative to syntheticdrugs. Lathyrus linifolius is a plant whose tubers …
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Mapping the Feeding Circuitry in the Mouse and Human Brain
The prevalence of obesity and its associated comorbidities has significantly grown over the last 50 years, imposing a great burden on people’s health. Consequently, understanding the mechanisms by which energy intake and bodyweight are controlled is extremely important to help us to further improve …
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Oligomeric cocoa procyanidins possess enhanced bioactivity compared to monomeric and polymeric cocoa procyanidins for preventing the development of obesity, insulin resistance, and impaired glucose tolerance during high-fat feeding
… flavanols. However, research on the potential anti-obesity and anti-diabetic health benefits of cocoa flavanols is lacking in the literature. Furthermore, the effect that the size of these flavanols has on the extent of its beneficial properties is also unclear. The objective of this study was …
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Investigating adipose tissue angiogenesis in obesity reveals a novel role for thrombospondin-1.
Obesity is a major health problem that has reached epidemic proportions worldwide.Therapeutic intervention for obesity has proven extremely challenging. Obesity is a complex trait involving the interaction of genes involved in fundamental aspects of weight maintenance, exposure to an environment …
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The role of brown adipose tissue on substrate metabolism and insulin sensitivity in humans
… the notion that human BAT may function as an anti-obesity and anti-diabetic tissue.
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Phosphate Tether-Mediated, One-Pot Metathesis Processes: Application in Small Molecule Synthesis
… the reported bicyclo[4.3.1]phosphate (both enantiomers) undergoes several selective transformations to access polyol building blocks that are present in a number of bioactive natural products. Application of this method to the total synthesis of the pancreatic lipase inhibitor …
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Anti-Inflammatory Effect of Berry Essences
… factors is one of the important roles for anti-inflammatory agents. For last two decades, researches about anti-inflammatory effect of bioactive compounds from fruits and vegetables have increased. Among fruits and vegetables, berries are one of the most consumed fruits in our diet and have …
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Is Being Overweight Bad for You? The Effects of Weight and Weight Status on Self-Reported Health
… and scientific studies – all decrying the “obesity epidemic” plaguing the United States. In this same period, mean Body Mass Indexes and rates of overweight and obesity in the US have either increased or remained steady, but have seen no wide-spread reversal in direction. Thus, despite …
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Social marketing and public health: an ethnographic investigation
… is the English Department of Health’s first anti-obesity social marketing programme. C4L multimedia advertising is found throughout the English landscape, converting the built and virtual environment into a moral space. However, a key characteristic is the way such a national remit is …
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