Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"anti-hypertensive"”.
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Gitelman & Gordon: Mirror image syndromes reveal the roles of WNKs in blood pressure homeostasis and novel anti-hypertensive targets
… inhibition of SPAK function as a promising anti-hypertensive strategy with multiple sites of action. To address these possibilities the work aimed to phenotype: (1) heterozygous CUL3$^{WT/\Delta403-459}$ mice to investigate a possible vascular contribution to PHAII pathophysiology, (2) …
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Fluid and blood pressure management in maintenance hemodialysis patients
… for managing polypharmacy and deprescribing anti-hypertensive medications. When patients transition from non-dialysis CKD to chronic HD therapy, the requirement for anti-hypertensive medications may change due to the removal of extracellular fluid by ultrafiltration and other factors. Because …
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Vascular remodelling in malignant hypertension
… hypertension (MH) fails to decline. Improved anti¬ hypertensive agents have reduced mortality, but the economic burden remains high due to complications such as end stage renal failure. Since the condition is initially asymptomatic, little is known about early pathogenesis. However the …
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Mechanisms by Which Exercise Training Attenuates Blood Pressure in Animals: Roles of Cytokines, Oxidative Stress, and Glycogen Synthase Kinase-3â
… billion people worldwide. Currently available anti-hypertensive medications are found to be effective in reducing blood pressure (BP), but still more than 50% of those diagnosed with hypertension fail to respond to these anti-hypertensive regimens. Although hypertension has multiple etiologies, …
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A quality improvement project evaluating the perioperative implementation of a hypertension management protocol by anaesthesiologists at seven government hospitals in the Western Cape. “a multi-center, cross-sectional quality improvement project: the peri-operative implementation of a hypertension protocol by anesthesiologists”
… and subsequent initiation or modification of anti-hypertensive therapy, or referral to a physician. The study was a multi-center, cross-sectional quality improvement project in seven hospitals in the Western Cape, South Africa. On the day before scheduled elective surgery, adult inpatients had …
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Combined Relaxation and Cognitive Restructuring Skills in the Control of Borderline Essential Hypertension
… control of non-medicated, borderline essential hypertensives. Few studies in the literature (Chesney & Black, 1986; Seer & Raeburn, 1980) have targeted the borderline hypertensive population, and most are confounded by the concurrent use of anti-hypertensive medication. In the present study, 16 …
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Role of Toll-Like Receptor 4 in Pathophysiology of Hypertension
… 1 billion people worldwide. Currently available anti-hypertensive medica-tions are found to be effective in reducing blood pressure (BP), but still more than 50% of those diagnosed with hypertension fail to respond to these anti-hypertensive regimens. Very recently, role of toll-like receptors …
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Reversed-Phase HPLC Determination of Alliin in Diverse Varieties of Fresh Garlic and Commercial Garlic Products.
… risk in humans, improving immune system, and anti-microbial, anti-oxidant, and anti-hypertensive activities. The quality of fresh garlic and garlic products is usually related to its alliin content and allicin release potential. This research presents a simple, rapid, and precise HPLC …
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Physico-chemical and therapeutic properties of low-fat yogurt as influenced by fat replacers, exopolysaccharides and probiotics
… along with probiotics and to establish its antihypertensive property in vitro and in vivo. The specific aims of this project were: a) to select suitable strains of S. thermophilus and L. delbrueckii ssp. bulgaricus and of probiotics (L. casei, L. acidophilus and Bifidobacterium longum) based …
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Reprogramming the Tumor Microenvironment in Desmoplastic Tumors to Potentiate Cancer Immunotherapy
… material that can be conjugated with a class of anti-hypertensive drugs to target tumor desmoplasia, enhance anti-tumor activity of T-lymphocytes, and prolong animal survival when combined with ICB in mouse models of mBC. Next, we investigated the effects of targeting CXCR4/CXCL12 signaling, a …
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Development of fixed dose combinations using advanced engineering technologies
… adherence.<br/><br/>Furthermore, a range of anti-hypertensive drugs were used throughout various chapters. These active pharmaceutical ingredients presented a range of therapeutic and manufacturing problems including; poor water solubility, thermolability or having a short half-life. …
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Guanabenz Reduces Hyperactivity and Neuroinflammation Caused by Latent Toxoplasmosis in Mice
… question. We have previously shown that the anti-hypertensive drug guanabenz reduces Toxoplasma cyst burden in the brains of BALB/c mice, providing a means to examine whether brain cyst depletion reverses behavioral changes. We used two mouse strains (BALB/c and C57BL/6) differing in their …
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Vascular and metabolic profile of 5-year sustained hypertensive versus normotensive black South Africans
… Whether the increased arterial stiffness seen in hypertensives are due to structural or functional adaptations in the vasculature is uncertain. Hypertension is more common in blacks and they have an increased arterial stiffness and higher stroke prevalence than white populations. Arterial …
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Pilot comparison of clinical effects and compliance with commonly prescribed antihypertensive drugs in HIV hypertensive patients at University Teaching Hospital
… effects and compliance with commonly prescribed antihypertensive drugs in HIV hypertensive patients at UTH. By Dr Takondwa Ngulube Chidumayo HIV infection and hypertension disproportionately affect sub-Saharan Africa including Zambia. The challenges of effectively treating patients with these …
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Pilot comparison of clinical effects and compliance with commonly prescribed antihypertensive drugs in HIV hypertensive patients at University Teaching Hospital
… effects and compliance with commonly prescribed antihypertensive drugs in HIV hypertensive patients at UTH. By Dr Takondwa Ngulube Chidumayo HIV infection and hypertension disproportionately affect sub-Saharan Africa including Zambia. The challenges of effectively treating patients with these …
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Diabetic retinopathy among patients attending university teaching hospitals adult hospital medical clinic in Lusaka
… common (115=54.5%) diabetes control measure. Anti-hypertensive medication was being used by 87 participants (40.9%). Median glycated haemoglobin level was high at 8.1%. One hundred sixty-three participants (76.5%) had normal VA and six (2.8%) were blind. The prevalence of DR in this study was …
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Diabetic retinopathy among patients attending university teaching hospitals adult hospital medical clinic in Lusaka
… common (115=54.5%) diabetes control measure. Anti-hypertensive medication was being used by 87 participants (40.9%). Median glycated haemoglobin level was high at 8.1%. One hundred sixty-three participants (76.5%) had normal VA and six (2.8%) were blind. The prevalence of DR in this study was …
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The nutritional knowledge and consumption of blackjack by hypertensive patients in Vhembe District, Limpopo Province, South Africa
… in particular, have been shown to possess anti-hypertensive properties that are attributed to bioactive chemical substances such as phytochemicals, fiber, antioxidants as well as micronutrients that include potassium, magnesium, calcium, vitamin C, zinc, iron and copper. The use of …
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Comparative effects of calcium channel antagonism and beta-1 selective blockade on exercise performance in physically active hypertensive patients
… participate in habitual physical exercise. Many hypertensive patients who exercise will require anti-hypertensive medication. However, some antihypertensive agents cause fatigue during exercise. In order for patients to gain the full benefits of an active lifestyle, it is important that the …
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Transcendental meditation on blood pressure in hypertensive patients as an alternative/adjuvant to pharmacotherapy
… activity) and the use of pharmacologic agents. Anti-hypertensive medications are very effective in lowering BP and preventing CVD. Unfortunately, HTN often goes untreated as there are many parts of the developing world that do not have adequate access or utilization of these therapies. Without …
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