Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"anti-fibrotic effects"”.
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UNVEILING NOVEL CARDIOPROTECTIVE EFFECTS OF GYY4137, A SLOW-RELEASING HYDROGEN SULFIDE DONOR, AND THEIR RELATIONSHIP TO NEUROHORMONAL MODULATION AND MICRORNA PROFILES DURING MYOCARDIAL ISCHEMIC INJURY.
… was designed to investigate the cardioprotective effects of slow-releasing water-soluble H2S donor GYY4137 (GYY) and their relationship to neurohormonal modulation and microRNA profiles during myocardial ischemic injury. In this study, it was found that treatment with GYY (100mg/kg/48hrs) …
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Therapeutic potential of the anti-fibrotic drug Suberanilohydroxamic acid (SAHA) in canine corneal fibrosis
… the molecular mechanisms mediating the antifibrotic effect of SAHA in the canine cornea using an in vitro model and (2) to develop a novel in vivo model of corneal fibrosis in dogs utilizing alkali burn and assess the ability of SAHA to inhibit fibrosis using this canine model. Methods: …
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A MECHANISM FOR CORTICAL BONE STEM CELL-DERIVED EXOSOMES’ THERAPEUTIC EFFECT ON POST-MYOCARDIAL INFARCTION REPERFUSION INJURY AND CARDIAC REMODELING
… and in an in vivo post-I/R study in mice. The effects of CBSCs and CBSC-derived exosomes on cardiac fibroblasts was determined. The aim was to broaden our understanding of the mechanism by which CBSCs exert their anti-fibrotic effects. Methods and Results: We investigated the effects of mouse …
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Corneal fibrosis therapies and investigations in the canine corna in vitro
… 1: ABSTRACT Purpose: To evaluate the safety and anti-fibrotic effects of the drugs, angiotensin-converting enzyme inhibitor (ACE-I) lisinopril and rho-kinase inhibitor (ROCK-I) fasudil, alone and in combination, on the canine cornea using an established in vitro model. Methods: To test the safety …