Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"anti-adhesive"”.
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Anti-Adhesive Si-and F-Doped DLC Coatings and Micro-Nanostructured Surfaces for Medical Implants
… coatings and micro-nanostructured surfaces with anti-bacterial properties for biomedical applications. In this study a DLC coating and Si- and F- doped DLC coatings with various Si and F contents were prepared by a radio frequency plasma-enhanced chemical vapor deposition (rf-PECVD) technology. …
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Small bowel obstruction and toxicity of a new model of adhesion prevention
… The burden of postoperative adhesions is substantial and there is a need for an adhesion preventive agent that can be used in different clinical situations and reduce the clinical complications caused by adhesions, ie SBO, infertility and chronic abdominal pain. Previous experimental studies …
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The Biophysical Role of the Cellular Glycocalyx: Engineering Glycoproteins to Control Cell-Surface Properties
… applications. Taking advantage of the anti-adhesive properties of mucin, we apply mucin expression as an innovative technology for reduced aggregation of cells grown in suspension in bioreactors. With our unique viewpoint of the glycocalyx from a physical perspective, we apply polymer …
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Bacterial adhesion in structured environments
… and bacterial surface properties that enable adhesive interactions. We herein design model surfaces and examine the interplay between micro-scale geometry, surface energy and bacterial surface properties with respect to adhesion, with the ultimate goal of understanding bacterial adhesion in …
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Hydrogen silsesquioxane (HSQ) for use in nano imprint lithography
… of NIL are the creation of imprinters and the anti-adhesive layers used to protect the imprinters. Hydrogen silsesquioxane (HSQ) is a spin on dielectric with properties of a negative e-beam resist which can generate a SiO2 like material. This can then be used as an imprinter for NIL work with …
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Human milk as a source of tumor killing molecules. From MAL to HAMLET.
… oleic acid, was discovered by serendipity when anti-adhesive properties of human milk were examined. HAMLET kills tumor cells but not healthy differentiated cells. Native alphalactalbumin (HLA) can be conveted to HAMLET by a two-step process including: 1) calcium ion removal inducing a teritary …
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Progress in synthetic materials for abdominal wall repair
… of the patch. The interaction between an anti-adhesive barrier layer of ePTFE and small pore polypropylene causes an extremely intense inflammatory reaction and fibrosis formation leading to shrinkage, inadequate mesh overlap and clinical recurrences. In conclusion, new materials with a …
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GLYCOMIMETIC LIGANDS TARGETING BACTERIAL LECTINS: RATIONAL DESIGN, SYNTHESIS AND BIOPHYSICAL EVALUATION
… increasingly difficult to treat due to rising antibacterial resistance. In this context, anti-adhesion therapy (AAT) is emerging as a complementary approach to traditional antibiotics. AAT aims to inhibit the adhesion of pathogens to host cells, which is one of the initial and essential steps …
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Modeling mammary epithelial cell polarization and the role of podocalyxin in breast tumor progression
… to ductal tumor progression. Podocalyxin is an anti-adhesive glycoprotein that may be involved, as it is important in epithelial morphogenesis, and its overexpression in clinical breast tumors is associated with poor outcome. Despite this, overexpression of podocalyxin in normal mammary …
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Anti-cancerous and anti-metastatic effects of Corchorus Olitorius on breast cancer cell lines
… The investigation aimed to explore its potential anti-cancer effects on selected breast cancer cell lines: MCF-7, MDA-MB-231 and MDA-MB-468. Acetone, hexane and methanol were used to extract bioactive compounds from C. olitorius leaves based on their solubility. These extracts were subsequently …
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A multi-disciplinary study of insect adhesion : functional biomechanics and applications
… of the species as a whole. To achieve this adhesive ability insects utilise a 'wet' adhesive system, making use of specialised functional adhesive pad structures which deploy a liquid secretion to the contact zone which aids adhesion through capillary and viscous forces. These attachment …
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Cranberry metabolites with urinary anti-adhesion activity
… via catheter. Urine fractions were tested for anti-adhesion activity using a human red blood cell (HRBC) anti-agglutination assay with uropathogenic P-fimbriated E. coli. Active urine fractions but not control urine or inactive fractions were found to contain complex mixtures of …
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Analysis of phenolics and other phytochemicals in selected Malaysian traditional vegetables and their activities in vitro
… study were to investigate, determine and quantify the phytochemicals, particularly phenolic compounds, in the seven samples from five species of selected Malaysian traditional vegetables (Anacardium occidentale, Centella asiatica, Colubrina asiatica, Pluchea indica and Premna cordifolia) and …
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INTEGRIN ALPHAVBETA3 AS THERAPEUTIC TARGET AND IMAGING BIOMARKER FOR VASCULAR ENDOTHELIAL CELLS AND CANCER EPITHELIAL CELLS
… diseases. Apart from function blocking antibodies, integrin antagonists comprise synthetic peptides and peptidomimetics. Synthetic peptides mimic the structure of natural integrin binding ligands. The largest class of synthetic peptides so far developed comprises RGD peptides, given that …
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Early nutrition affects intestinal development and immune response in the neonatal piglet
… the growth of Bifidobacteria, acting as anti-adhesive and anti-microbial factors against pathogens, modulating immune development, and perhaps even providing nutrients for brain development (Bode, 2012). Prebiotics are routinely added to infant formula to mimic the actions of HMOs. In …