Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"anti-CRISPRs"”.
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Anti-CRISPRs and CRISPR-Cas: Characterization and Biotechnology
… small protein inhibitors of CRISPR-Cas called anti-CRISPRs. In the first section of my work, I characterize the structure, function, and mechanism of action for an anti-CRISPR that inhibits the type I-E CRISPR-Cas system of Pseudomonas aeruginosa strain 4386. I show that beyond simply …
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Uncovering New Mechanisms of Type III CRISPR-Cas System Inhibition and Effector Function
… regularly interspaced short palindromic repeats (CRISPRs) and a set of genes that encode CRISPR-associated (Cas) proteins. While there are seven distinct types of CRISPR-Cas systems identified thus far, we focus on specifically the type III CRISPR system which contains a multi-protein effector …